Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DPYSL3 (dihydropyrimidinase like 3)

Identity

Alias_namesdihydropyrimidinase-like 3
Alias_symbol (synonym)DRP-3
ULIP
CRMP4
Other aliasCRMP-4
DRP3
LCRMP
ULIP-1
HGNC (Hugo) DPYSL3
LocusID (NCBI) 1809
Atlas_Id 45599
Location 5q32  [Link to chromosome band 5q32]
Location_base_pair Starts at 147390808 and ends at 147510056 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DPYSL3 (5q32) / DCTN1 (2p13.1)DPYSL3 (5q32) / DNAAF5 (7p22.3)DPYSL3 (5q32) / DPYSL3 (5q32)
DPYSL3 (5q32) / JAKMIP2 (5q32)DPYSL3 (5q32) / SFTPB (2p11.2)DPYSL3 (5q32) / VPS37B (12q24.31)
DPYSL3 (5q32) / ZNF226 (19q13.31)ELL3 (15q15.3) / DPYSL3 (5q32)FBN1 (15q21.1) / DPYSL3 (5q32)
JAKMIP2 (5q32) / DPYSL3 (5q32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPYSL3   3015
Cards
Entrez_Gene (NCBI)DPYSL3  1809  dihydropyrimidinase like 3
AliasesCRMP-4; CRMP4; DRP-3; DRP3; 
LCRMP; ULIP; ULIP-1
GeneCards (Weizmann)DPYSL3
Ensembl hg19 (Hinxton)ENSG00000113657 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113657 [Gene_View]  chr5:147390808-147510056 [Contig_View]  DPYSL3 [Vega]
ICGC DataPortalENSG00000113657
TCGA cBioPortalDPYSL3
AceView (NCBI)DPYSL3
Genatlas (Paris)DPYSL3
WikiGenes1809
SOURCE (Princeton)DPYSL3
Genetics Home Reference (NIH)DPYSL3
Genomic and cartography
GoldenPath hg38 (UCSC)DPYSL3  -     chr5:147390808-147510056 -  5q32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DPYSL3  -     5q32   [Description]    (hg19-Feb_2009)
EnsemblDPYSL3 - 5q32 [CytoView hg19]  DPYSL3 - 5q32 [CytoView hg38]
Mapping of homologs : NCBIDPYSL3 [Mapview hg19]  DPYSL3 [Mapview hg38]
OMIM601168   
Gene and transcription
Genbank (Entrez)AI570709 AK297223 BC039006 BC077077 CA424493
RefSeq transcript (Entrez)NM_001197294 NM_001387
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DPYSL3
Cluster EST : UnigeneHs.519659 [ NCBI ]
CGAP (NCI)Hs.519659
Alternative Splicing GalleryENSG00000113657
Gene ExpressionDPYSL3 [ NCBI-GEO ]   DPYSL3 [ EBI - ARRAY_EXPRESS ]   DPYSL3 [ SEEK ]   DPYSL3 [ MEM ]
Gene Expression Viewer (FireBrowse)DPYSL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1809
GTEX Portal (Tissue expression)DPYSL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14195   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14195  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14195
Splice isoforms : SwissVarQ14195
PhosPhoSitePlusQ14195
Domains : Interpro (EBI)Amidohydro-rel    DRP3    Hydantoinase/dihydroPyrase    Metal-dep_hydrolase_composite    Metal_Hydrolase   
Domain families : Pfam (Sanger)Amidohydro_1 (PF01979)   
Domain families : Pfam (NCBI)pfam01979   
Conserved Domain (NCBI)DPYSL3
DMDM Disease mutations1809
Blocks (Seattle)DPYSL3
PDB (SRS)4BKN    4CNS    4CNT    4CNU   
PDB (PDBSum)4BKN    4CNS    4CNT    4CNU   
PDB (IMB)4BKN    4CNS    4CNT    4CNU   
PDB (RSDB)4BKN    4CNS    4CNT    4CNU   
Structural Biology KnowledgeBase4BKN    4CNS    4CNT    4CNU   
SCOP (Structural Classification of Proteins)4BKN    4CNS    4CNT    4CNU   
CATH (Classification of proteins structures)4BKN    4CNS    4CNT    4CNU   
SuperfamilyQ14195
Human Protein AtlasENSG00000113657
Peptide AtlasQ14195
HPRD03104
IPIIPI00872788   IPI01014594   IPI01019022   IPI00029111   IPI00816386   IPI00975764   IPI00980201   
Protein Interaction databases
DIP (DOE-UCLA)Q14195
IntAct (EBI)Q14195
FunCoupENSG00000113657
BioGRIDDPYSL3
STRING (EMBL)DPYSL3
ZODIACDPYSL3
Ontologies - Pathways
QuickGOQ14195
Ontology : AmiGOprotein binding  extracellular space  cytosol  cytosol  positive regulation of neuron projection development  negative regulation of neuron projection development  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds  SH3 domain binding  lamellipodium  negative regulation of cell migration  growth cone  filamin binding  filamentous actin  chondroitin sulfate binding  cell body  neuron development  response to axon injury  actin filament bundle assembly  protein homooligomerization  positive regulation of filopodium assembly  actin crosslink formation  exocytic vesicle  cellular response to cytokine stimulus  
Ontology : EGO-EBIprotein binding  extracellular space  cytosol  cytosol  positive regulation of neuron projection development  negative regulation of neuron projection development  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds  SH3 domain binding  lamellipodium  negative regulation of cell migration  growth cone  filamin binding  filamentous actin  chondroitin sulfate binding  cell body  neuron development  response to axon injury  actin filament bundle assembly  protein homooligomerization  positive regulation of filopodium assembly  actin crosslink formation  exocytic vesicle  cellular response to cytokine stimulus  
NDEx NetworkDPYSL3
Atlas of Cancer Signalling NetworkDPYSL3
Wikipedia pathwaysDPYSL3
Orthology - Evolution
OrthoDB1809
GeneTree (enSembl)ENSG00000113657
Phylogenetic Trees/Animal Genes : TreeFamDPYSL3
HOVERGENQ14195
HOGENOMQ14195
Homologs : HomoloGeneDPYSL3
Homology/Alignments : Family Browser (UCSC)DPYSL3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPYSL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPYSL3
dbVarDPYSL3
ClinVarDPYSL3
1000_GenomesDPYSL3 
Exome Variant ServerDPYSL3
ExAC (Exome Aggregation Consortium)DPYSL3 (select the gene name)
Genetic variants : HAPMAP1809
Genomic Variants (DGV)DPYSL3 [DGVbeta]
DECIPHERDPYSL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDPYSL3 
Mutations
ICGC Data PortalDPYSL3 
TCGA Data PortalDPYSL3 
Broad Tumor PortalDPYSL3
OASIS PortalDPYSL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPYSL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDPYSL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DPYSL3
DgiDB (Drug Gene Interaction Database)DPYSL3
DoCM (Curated mutations)DPYSL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPYSL3 (select a term)
intoGenDPYSL3
Cancer3DDPYSL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601168   
Orphanet
MedgenDPYSL3
Genetic Testing Registry DPYSL3
NextProtQ14195 [Medical]
TSGene1809
GENETestsDPYSL3
Target ValidationDPYSL3
Huge Navigator DPYSL3 [HugePedia]
snp3D : Map Gene to Disease1809
BioCentury BCIQDPYSL3
ClinGenDPYSL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1809
Chemical/Pharm GKB GenePA27473
Clinical trialDPYSL3
Miscellaneous
canSAR (ICR)DPYSL3 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPYSL3
EVEXDPYSL3
GoPubMedDPYSL3
iHOPDPYSL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:05:59 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.