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DPYSL4 (dihydropyrimidinase like 4)

Identity

Alias_namesdihydropyrimidinase-like 4
Alias_symbol (synonym)ULIP4
DRP-4
Other aliasCRMP3
HGNC (Hugo) DPYSL4
LocusID (NCBI) 10570
Atlas_Id 62633
Location 10q26.3  [Link to chromosome band 10q26]
Location_base_pair Starts at 132186910 and ends at 132205776 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BICC1 (10q21.1) / DPYSL4 (10q26.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPYSL4   3016
Cards
Entrez_Gene (NCBI)DPYSL4  10570  dihydropyrimidinase like 4
AliasesCRMP3; DRP-4; ULIP4
GeneCards (Weizmann)DPYSL4
Ensembl hg19 (Hinxton)ENSG00000151640 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151640 [Gene_View]  chr10:132186910-132205776 [Contig_View]  DPYSL4 [Vega]
ICGC DataPortalENSG00000151640
TCGA cBioPortalDPYSL4
AceView (NCBI)DPYSL4
Genatlas (Paris)DPYSL4
WikiGenes10570
SOURCE (Princeton)DPYSL4
Genetics Home Reference (NIH)DPYSL4
Genomic and cartography
GoldenPath hg38 (UCSC)DPYSL4  -     chr10:132186910-132205776 +  10q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DPYSL4  -     10q26.3   [Description]    (hg19-Feb_2009)
EnsemblDPYSL4 - 10q26.3 [CytoView hg19]  DPYSL4 - 10q26.3 [CytoView hg38]
Mapping of homologs : NCBIDPYSL4 [Mapview hg19]  DPYSL4 [Mapview hg38]
OMIM608407   
Gene and transcription
Genbank (Entrez)AB006713 BC029280 BC136329 BC136330 BC142974
RefSeq transcript (Entrez)NM_006426
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DPYSL4
Cluster EST : UnigeneHs.100058 [ NCBI ]
CGAP (NCI)Hs.100058
Alternative Splicing GalleryENSG00000151640
Gene ExpressionDPYSL4 [ NCBI-GEO ]   DPYSL4 [ EBI - ARRAY_EXPRESS ]   DPYSL4 [ SEEK ]   DPYSL4 [ MEM ]
Gene Expression Viewer (FireBrowse)DPYSL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10570
GTEX Portal (Tissue expression)DPYSL4
Human Protein AtlasENSG00000151640-DPYSL4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14531   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14531  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14531
Splice isoforms : SwissVarO14531
PhosPhoSitePlusO14531
Domains : Interpro (EBI)Amidohydro-rel    DRP4    Hydantoinase/dihydroPyrase    Metal-dep_hydrolase_composite    Metal_Hydrolase   
Domain families : Pfam (Sanger)Amidohydro_1 (PF01979)   
Domain families : Pfam (NCBI)pfam01979   
Conserved Domain (NCBI)DPYSL4
DMDM Disease mutations10570
Blocks (Seattle)DPYSL4
SuperfamilyO14531
Human Protein Atlas [tissue]ENSG00000151640-DPYSL4 [tissue]
Peptide AtlasO14531
HPRD07463
IPIIPI00022388   IPI00514623   
Protein Interaction databases
DIP (DOE-UCLA)O14531
IntAct (EBI)O14531
FunCoupENSG00000151640
BioGRIDDPYSL4
STRING (EMBL)DPYSL4
ZODIACDPYSL4
Ontologies - Pathways
QuickGOO14531
Ontology : AmiGOprotein binding  cytosol  nervous system development  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds  filamin binding  neuron death  neuron projection guidance  
Ontology : EGO-EBIprotein binding  cytosol  nervous system development  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds  filamin binding  neuron death  neuron projection guidance  
NDEx NetworkDPYSL4
Atlas of Cancer Signalling NetworkDPYSL4
Wikipedia pathwaysDPYSL4
Orthology - Evolution
OrthoDB10570
GeneTree (enSembl)ENSG00000151640
Phylogenetic Trees/Animal Genes : TreeFamDPYSL4
HOVERGENO14531
HOGENOMO14531
Homologs : HomoloGeneDPYSL4
Homology/Alignments : Family Browser (UCSC)DPYSL4
Gene fusions - Rearrangements
Tumor Fusion PortalDPYSL4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPYSL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPYSL4
dbVarDPYSL4
ClinVarDPYSL4
1000_GenomesDPYSL4 
Exome Variant ServerDPYSL4
ExAC (Exome Aggregation Consortium)ENSG00000151640
GNOMAD BrowserENSG00000151640
Genetic variants : HAPMAP10570
Genomic Variants (DGV)DPYSL4 [DGVbeta]
DECIPHERDPYSL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDPYSL4 
Mutations
ICGC Data PortalDPYSL4 
TCGA Data PortalDPYSL4 
Broad Tumor PortalDPYSL4
OASIS PortalDPYSL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPYSL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDPYSL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DPYSL4
DgiDB (Drug Gene Interaction Database)DPYSL4
DoCM (Curated mutations)DPYSL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPYSL4 (select a term)
intoGenDPYSL4
Cancer3DDPYSL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608407   
Orphanet
DisGeNETDPYSL4
MedgenDPYSL4
Genetic Testing Registry DPYSL4
NextProtO14531 [Medical]
TSGene10570
GENETestsDPYSL4
Target ValidationDPYSL4
Huge Navigator DPYSL4 [HugePedia]
snp3D : Map Gene to Disease10570
BioCentury BCIQDPYSL4
ClinGenDPYSL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10570
Chemical/Pharm GKB GenePA27474
Clinical trialDPYSL4
Miscellaneous
canSAR (ICR)DPYSL4 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPYSL4
EVEXDPYSL4
GoPubMedDPYSL4
iHOPDPYSL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 19:26:57 CET 2017

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