Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DRAXIN (dorsal inhibitory axon guidance protein)

Identity

Alias (NCBI)AGPA3119
C1orf187
UNQ3119
neucrin
HGNC (Hugo) DRAXIN
HGNC Alias symbFLJ34999
Draxin
Neucrin
HGNC Alias namedorsal repulsive axon guidance protein
 neural tissue-specific cysteine-rich protein
HGNC Previous nameC1orf187
HGNC Previous namechromosome 1 open reading frame 187
LocusID (NCBI) 374946
Atlas_Id 62637
Location 1p36.22  [Link to chromosome band 1p36]
Location_base_pair Starts at 11691724 and ends at 11720279 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DRAXIN (1p36.22) / AGTRAP (1p36.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)DRAXIN   25054
Cards
Entrez_Gene (NCBI)DRAXIN    dorsal inhibitory axon guidance protein
AliasesAGPA3119; C1orf187; UNQ3119; neucrin
GeneCards (Weizmann)DRAXIN
Ensembl hg19 (Hinxton)ENSG00000162490 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162490 [Gene_View]  ENSG00000162490 [Sequence]  chr1:11691724-11720279 [Contig_View]  DRAXIN [Vega]
ICGC DataPortalENSG00000162490
TCGA cBioPortalDRAXIN
AceView (NCBI)DRAXIN
Genatlas (Paris)DRAXIN
SOURCE (Princeton)DRAXIN
Genetics Home Reference (NIH)DRAXIN
Genomic and cartography
GoldenPath hg38 (UCSC)DRAXIN  -     chr1:11691724-11720279 +  1p36.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DRAXIN  -     1p36.22   [Description]    (hg19-Feb_2009)
GoldenPathDRAXIN - 1p36.22 [CytoView hg19]  DRAXIN - 1p36.22 [CytoView hg38]
ImmunoBaseENSG00000162490
genome Data Viewer NCBIDRAXIN [Mapview hg19]  
OMIM612682   
Gene and transcription
Genbank (Entrez)AB301919 AK075558 AK092318 AK311439 AY358750
RefSeq transcript (Entrez)NM_198545
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DRAXIN
Alternative Splicing GalleryENSG00000162490
Gene ExpressionDRAXIN [ NCBI-GEO ]   DRAXIN [ EBI - ARRAY_EXPRESS ]   DRAXIN [ SEEK ]   DRAXIN [ MEM ]
Gene Expression Viewer (FireBrowse)DRAXIN [ Firebrowse - Broad ]
GenevisibleExpression of DRAXIN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)374946
GTEX Portal (Tissue expression)DRAXIN
Human Protein AtlasENSG00000162490-DRAXIN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NBI3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NBI3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NBI3
Splice isoforms : SwissVarQ8NBI3
PhosPhoSitePlusQ8NBI3
Domains : Interpro (EBI)Draxin   
Domain families : Pfam (Sanger)Draxin (PF15550)   
Domain families : Pfam (NCBI)pfam15550   
Conserved Domain (NCBI)DRAXIN
Blocks (Seattle)DRAXIN
PDB (RSDB)6FKQ   
PDB Europe6FKQ   
PDB (PDBSum)6FKQ   
PDB (IMB)6FKQ   
Structural Biology KnowledgeBase6FKQ   
SCOP (Structural Classification of Proteins)6FKQ   
CATH (Classification of proteins structures)6FKQ   
SuperfamilyQ8NBI3
Human Protein Atlas [tissue]ENSG00000162490-DRAXIN [tissue]
Peptide AtlasQ8NBI3
HPRD11844
IPIIPI00301098   
Protein Interaction databases
DIP (DOE-UCLA)Q8NBI3
IntAct (EBI)Q8NBI3
BioGRIDDRAXIN
STRING (EMBL)DRAXIN
ZODIACDRAXIN
Ontologies - Pathways
QuickGOQ8NBI3
Ontology : AmiGOprotein binding  extracellular region  extracellular region  axon guidance  axon guidance  Wnt signaling pathway  dorsal spinal cord development  dorsal spinal cord development  commissural neuron differentiation in spinal cord  commissural neuron differentiation in spinal cord  negative regulation of axon extension  forebrain development  forebrain development  negative regulation of neuron apoptotic process  negative regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIprotein binding  extracellular region  extracellular region  axon guidance  axon guidance  Wnt signaling pathway  dorsal spinal cord development  dorsal spinal cord development  commissural neuron differentiation in spinal cord  commissural neuron differentiation in spinal cord  negative regulation of axon extension  forebrain development  forebrain development  negative regulation of neuron apoptotic process  negative regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  
NDEx NetworkDRAXIN
Atlas of Cancer Signalling NetworkDRAXIN
Wikipedia pathwaysDRAXIN
Orthology - Evolution
OrthoDB374946
GeneTree (enSembl)ENSG00000162490
Phylogenetic Trees/Animal Genes : TreeFamDRAXIN
HOGENOMQ8NBI3
Homologs : HomoloGeneDRAXIN
Homology/Alignments : Family Browser (UCSC)DRAXIN
Gene fusions - Rearrangements
Fusion : QuiverDRAXIN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDRAXIN [hg38]
dbVarDRAXIN
ClinVarDRAXIN
MonarchDRAXIN
1000_GenomesDRAXIN 
Exome Variant ServerDRAXIN
GNOMAD BrowserENSG00000162490
Varsome BrowserDRAXIN
Genomic Variants (DGV)DRAXIN [DGVbeta]
DECIPHERDRAXIN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDRAXIN 
Mutations
ICGC Data PortalDRAXIN 
TCGA Data PortalDRAXIN 
Broad Tumor PortalDRAXIN
OASIS PortalDRAXIN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDRAXIN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDRAXIN
Mutations and Diseases : HGMDDRAXIN
BioMutasearch DRAXIN
DgiDB (Drug Gene Interaction Database)DRAXIN
DoCM (Curated mutations)DRAXIN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DRAXIN (select a term)
intoGenDRAXIN
Cancer3DDRAXIN(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612682   
Orphanet
DisGeNETDRAXIN
MedgenDRAXIN
Genetic Testing Registry DRAXIN
NextProtQ8NBI3 [Medical]
GENETestsDRAXIN
Target ValidationDRAXIN
Huge Navigator DRAXIN [HugePedia]
ClinGenDRAXIN
Clinical trials, drugs, therapy
MyCancerGenomeDRAXIN
Protein Interactions : CTD
Pharm GKB GenePA142672435
Clinical trialDRAXIN
Miscellaneous
canSAR (ICR)DRAXIN (select the gene name)
HarmonizomeDRAXIN
DataMed IndexDRAXIN
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDRAXIN
EVEXDRAXIN
GoPubMedDRAXIN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 16:52:19 CET 2020

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