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DRG2 (developmentally regulated GTP binding protein 2)

Identity

Alias_namesdevelopmentally regulated GTP-binding protein 2
Other alias-
HGNC (Hugo) DRG2
LocusID (NCBI) 1819
Atlas_Id 56604
Location 17p11.2  [Link to chromosome band 17p11]
Location_base_pair Starts at 18087867 and ends at 18107985 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DRG2 (17p11.2) / ZNF624 (17p11.2)LLGL1 (17p11.2) / DRG2 (17p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DRG2   3030
Cards
Entrez_Gene (NCBI)DRG2  1819  developmentally regulated GTP binding protein 2
Aliases
GeneCards (Weizmann)DRG2
Ensembl hg19 (Hinxton)ENSG00000108591 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108591 [Gene_View]  chr17:18087867-18107985 [Contig_View]  DRG2 [Vega]
ICGC DataPortalENSG00000108591
TCGA cBioPortalDRG2
AceView (NCBI)DRG2
Genatlas (Paris)DRG2
WikiGenes1819
SOURCE (Princeton)DRG2
Genetics Home Reference (NIH)DRG2
Genomic and cartography
GoldenPath hg38 (UCSC)DRG2  -     chr17:18087867-18107985 +  17p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DRG2  -     17p11.2   [Description]    (hg19-Feb_2009)
EnsemblDRG2 - 17p11.2 [CytoView hg19]  DRG2 - 17p11.2 [CytoView hg38]
Mapping of homologs : NCBIDRG2 [Mapview hg19]  DRG2 [Mapview hg38]
OMIM602986   
Gene and transcription
Genbank (Entrez)AB209340 AI478627 AK095755 AK295575 AK297569
RefSeq transcript (Entrez)NM_001330144 NM_001388
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DRG2
Cluster EST : UnigeneHs.78582 [ NCBI ]
CGAP (NCI)Hs.78582
Alternative Splicing GalleryENSG00000108591
Gene ExpressionDRG2 [ NCBI-GEO ]   DRG2 [ EBI - ARRAY_EXPRESS ]   DRG2 [ SEEK ]   DRG2 [ MEM ]
Gene Expression Viewer (FireBrowse)DRG2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1819
GTEX Portal (Tissue expression)DRG2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55039   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55039  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55039
Splice isoforms : SwissVarP55039
PhosPhoSitePlusP55039
Domaine pattern : Prosite (Expaxy)G_OBG (PS51710)    GTP1_OBG (PS00905)   
Domains : Interpro (EBI)G_OBG    GTP-binding_2    GTP1-OBG_CS    GTP_binding_domain    P-loop_NTPase    Small_GTP-bd_dom    TGS    TGS-like   
Domain families : Pfam (Sanger)MMR_HSR1 (PF01926)    MMR_HSR1_Xtn (PF16897)    TGS (PF02824)   
Domain families : Pfam (NCBI)pfam01926    pfam16897    pfam02824   
Conserved Domain (NCBI)DRG2
DMDM Disease mutations1819
Blocks (Seattle)DRG2
SuperfamilyP55039
Human Protein AtlasENSG00000108591
Peptide AtlasP55039
HPRD04286
IPIIPI00022697   IPI00556215   IPI00794194   
Protein Interaction databases
DIP (DOE-UCLA)P55039
IntAct (EBI)P55039
FunCoupENSG00000108591
BioGRIDDRG2
STRING (EMBL)DRG2
ZODIACDRG2
Ontologies - Pathways
QuickGOP55039
Ontology : AmiGOprotein binding  GTP binding  nucleoplasm  mitochondrion  cytosol  signal transduction  membrane  intracellular membrane-bounded organelle  
Ontology : EGO-EBIprotein binding  GTP binding  nucleoplasm  mitochondrion  cytosol  signal transduction  membrane  intracellular membrane-bounded organelle  
NDEx NetworkDRG2
Atlas of Cancer Signalling NetworkDRG2
Wikipedia pathwaysDRG2
Orthology - Evolution
OrthoDB1819
GeneTree (enSembl)ENSG00000108591
Phylogenetic Trees/Animal Genes : TreeFamDRG2
HOVERGENP55039
HOGENOMP55039
Homologs : HomoloGeneDRG2
Homology/Alignments : Family Browser (UCSC)DRG2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDRG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DRG2
dbVarDRG2
ClinVarDRG2
1000_GenomesDRG2 
Exome Variant ServerDRG2
ExAC (Exome Aggregation Consortium)DRG2 (select the gene name)
Genetic variants : HAPMAP1819
Genomic Variants (DGV)DRG2 [DGVbeta]
DECIPHERDRG2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDRG2 
Mutations
ICGC Data PortalDRG2 
TCGA Data PortalDRG2 
Broad Tumor PortalDRG2
OASIS PortalDRG2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDRG2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDRG2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DRG2
DgiDB (Drug Gene Interaction Database)DRG2
DoCM (Curated mutations)DRG2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DRG2 (select a term)
intoGenDRG2
Cancer3DDRG2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602986   
Orphanet
MedgenDRG2
Genetic Testing Registry DRG2
NextProtP55039 [Medical]
TSGene1819
GENETestsDRG2
Target ValidationDRG2
Huge Navigator DRG2 [HugePedia]
snp3D : Map Gene to Disease1819
BioCentury BCIQDRG2
ClinGenDRG2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1819
Chemical/Pharm GKB GenePA27484
Clinical trialDRG2
Miscellaneous
canSAR (ICR)DRG2 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDRG2
EVEXDRG2
GoPubMedDRG2
iHOPDRG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:31:45 CEST 2017

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