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DRGX (dorsal root ganglia homeobox)

Identity

Alias (NCBI)DRG11
PRRXL1
HGNC (Hugo) DRGX
HGNC Alias symbDRG11
HGNC Alias namepaired-like homeodomain trancription factor DRG11
HGNC Previous namePRRXL1
HGNC Previous namepaired related homeobox-like 1
LocusID (NCBI) 644168
Atlas_Id 62644
Location 10q11.23  [Link to chromosome band 10q11]
Location_base_pair Starts at 49364066 and ends at 49396089 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KTN1 (14q22.3) / DRGX (10q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)DRGX   21536
Cards
Entrez_Gene (NCBI)DRGX    dorsal root ganglia homeobox
AliasesDRG11; PRRXL1
GeneCards (Weizmann)DRGX
Ensembl hg19 (Hinxton)ENSG00000165606 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165606 [Gene_View]  ENSG00000165606 [Sequence]  chr10:49364066-49396089 [Contig_View]  DRGX [Vega]
ICGC DataPortalENSG00000165606
TCGA cBioPortalDRGX
AceView (NCBI)DRGX
Genatlas (Paris)DRGX
SOURCE (Princeton)DRGX
Genetics Home Reference (NIH)DRGX
Genomic and cartography
GoldenPath hg38 (UCSC)DRGX  -     chr10:49364066-49396089 -  10q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DRGX  -     10q11.23   [Description]    (hg19-Feb_2009)
GoldenPathDRGX - 10q11.23 [CytoView hg19]  DRGX - 10q11.23 [CytoView hg38]
ImmunoBaseENSG00000165606
Genome Data Viewer NCBIDRGX [Mapview hg19]  
OMIM606701   
Gene and transcription
Genbank (Entrez)DW009785 HY131276
RefSeq transcript (Entrez)NM_001080520 NM_001276451
Consensus coding sequences : CCDS (NCBI)DRGX
Gene ExpressionDRGX [ NCBI-GEO ]   DRGX [ EBI - ARRAY_EXPRESS ]   DRGX [ SEEK ]   DRGX [ MEM ]
Gene Expression Viewer (FireBrowse)DRGX [ Firebrowse - Broad ]
GenevisibleExpression of DRGX in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)644168
GTEX Portal (Tissue expression)DRGX
Human Protein AtlasENSG00000165606-DRGX [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA6NNA5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA6NNA5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA6NNA5
PhosPhoSitePlusA6NNA5
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    OAR (PS50803)   
Domains : Interpro (EBI)Homeobox-like_sf    Homeobox_CS    Homeobox_dom    OAR_dom   
Domain families : Pfam (Sanger)Homeodomain (PF00046)    OAR (PF03826)   
Domain families : Pfam (NCBI)pfam00046    pfam03826   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)DRGX
SuperfamilyA6NNA5
AlphaFold pdb e-kbA6NNA5   
Human Protein Atlas [tissue]ENSG00000165606-DRGX [tissue]
Protein Interaction databases
DIP (DOE-UCLA)A6NNA5
IntAct (EBI)A6NNA5
BioGRIDDRGX
STRING (EMBL)DRGX
ZODIACDRGX
Ontologies - Pathways
QuickGOA6NNA5
Ontology : AmiGOchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  neuron migration  nucleus  regulation of transcription by RNA polymerase II  axon guidance  detection of chemical stimulus  detection of temperature stimulus  dorsal spinal cord development  trigeminal nerve development  sensory perception of mechanical stimulus  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBIchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  neuron migration  nucleus  regulation of transcription by RNA polymerase II  axon guidance  detection of chemical stimulus  detection of temperature stimulus  dorsal spinal cord development  trigeminal nerve development  sensory perception of mechanical stimulus  sequence-specific double-stranded DNA binding  
NDEx NetworkDRGX
Atlas of Cancer Signalling NetworkDRGX
Wikipedia pathwaysDRGX
Orthology - Evolution
OrthoDB644168
GeneTree (enSembl)ENSG00000165606
Phylogenetic Trees/Animal Genes : TreeFamDRGX
Homologs : HomoloGeneDRGX
Homology/Alignments : Family Browser (UCSC)DRGX
Gene fusions - Rearrangements
Fusion : QuiverDRGX
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDRGX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DRGX
dbVarDRGX
ClinVarDRGX
MonarchDRGX
1000_GenomesDRGX 
Exome Variant ServerDRGX
GNOMAD BrowserENSG00000165606
Varsome BrowserDRGX
ACMGDRGX variants
VarityA6NNA5
Genomic Variants (DGV)DRGX [DGVbeta]
DECIPHERDRGX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDRGX 
Mutations
ICGC Data PortalDRGX 
TCGA Data PortalDRGX 
Broad Tumor PortalDRGX
OASIS PortalDRGX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDRGX  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDRGX
Mutations and Diseases : HGMDDRGX
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDRGX
DgiDB (Drug Gene Interaction Database)DRGX
DoCM (Curated mutations)DRGX
CIViC (Clinical Interpretations of Variants in Cancer)DRGX
Cancer3DDRGX
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606701   
Orphanet
DisGeNETDRGX
MedgenDRGX
Genetic Testing Registry DRGX
NextProtA6NNA5 [Medical]
GENETestsDRGX
Target ValidationDRGX
Huge Navigator DRGX [HugePedia]
ClinGenDRGX
Clinical trials, drugs, therapy
MyCancerGenomeDRGX
Protein Interactions : CTDDRGX
Pharm GKB GenePA162384078
PharosA6NNA5
Clinical trialDRGX
Miscellaneous
canSAR (ICR)DRGX
HarmonizomeDRGX
DataMed IndexDRGX
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDRGX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:48:25 CEST 2021

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