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DSCC1 (DNA replication and sister chromatid cohesion 1)

Identity

Alias_namesdefective in sister chromatid cohesion 1 homolog (S. cerevisiae)
Alias_symbol (synonym)DCC1
hDCC1
MGC5528
Other alias
HGNC (Hugo) DSCC1
LocusID (NCBI) 79075
Atlas_Id 54861
Location 8q24.12  [Link to chromosome band 8q24]
Location_base_pair Starts at 120846181 and ends at 120868170 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DSCC1 (8q24.12) / DSCC1 (8q24.12)TAF2 (8q24.12) / DSCC1 (8q24.12)TAF2 8q24.12 / DSCC1 8q24.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DSCC1   24453
Cards
Entrez_Gene (NCBI)DSCC1  79075  DNA replication and sister chromatid cohesion 1
AliasesDCC1
GeneCards (Weizmann)DSCC1
Ensembl hg19 (Hinxton)ENSG00000136982 [Gene_View]  chr8:120846181-120868170 [Contig_View]  DSCC1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000136982 [Gene_View]  chr8:120846181-120868170 [Contig_View]  DSCC1 [Vega]
ICGC DataPortalENSG00000136982
TCGA cBioPortalDSCC1
AceView (NCBI)DSCC1
Genatlas (Paris)DSCC1
WikiGenes79075
SOURCE (Princeton)DSCC1
Genetics Home Reference (NIH)DSCC1
Genomic and cartography
GoldenPath hg19 (UCSC)DSCC1  -     chr8:120846181-120868170 -  8q24.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DSCC1  -     8q24.12   [Description]    (hg38-Dec_2013)
EnsemblDSCC1 - 8q24.12 [CytoView hg19]  DSCC1 - 8q24.12 [CytoView hg38]
Mapping of homologs : NCBIDSCC1 [Mapview hg19]  DSCC1 [Mapview hg38]
OMIM613203   
Gene and transcription
Genbank (Entrez)AK054585 AK058129 AK074355 AK315356 AW149121
RefSeq transcript (Entrez)NM_024094
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)DSCC1
Cluster EST : UnigeneHs.315167 [ NCBI ]
CGAP (NCI)Hs.315167
Alternative Splicing GalleryENSG00000136982
Gene ExpressionDSCC1 [ NCBI-GEO ]   DSCC1 [ EBI - ARRAY_EXPRESS ]   DSCC1 [ SEEK ]   DSCC1 [ MEM ]
Gene Expression Viewer (FireBrowse)DSCC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79075
GTEX Portal (Tissue expression)DSCC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BVC3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BVC3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BVC3
Splice isoforms : SwissVarQ9BVC3
PhosPhoSitePlusQ9BVC3
Domains : Interpro (EBI)Sister_chromatid_cohesion_Dcc1   
Domain families : Pfam (Sanger)DUF2036 (PF09724)   
Domain families : Pfam (NCBI)pfam09724   
Conserved Domain (NCBI)DSCC1
DMDM Disease mutations79075
Blocks (Seattle)DSCC1
SuperfamilyQ9BVC3
Human Protein AtlasENSG00000136982
Peptide AtlasQ9BVC3
HPRD13123
IPIIPI00299884   
Protein Interaction databases
DIP (DOE-UCLA)Q9BVC3
IntAct (EBI)Q9BVC3
FunCoupENSG00000136982
BioGRIDDSCC1
STRING (EMBL)DSCC1
ZODIACDSCC1
Ontologies - Pathways
QuickGOQ9BVC3
Ontology : AmiGOchromosome, centromeric region  chromatin  DNA clamp loader activity  DNA clamp loader activity  protein binding  nucleoplasm  DNA replication  regulation of DNA replication  Ctf18 RFC-like complex  Ctf18 RFC-like complex  maintenance of mitotic sister chromatid cohesion  post-translational protein acetylation  single-stranded DNA-dependent ATPase activity  positive regulation of DNA-directed DNA polymerase activity  
Ontology : EGO-EBIchromosome, centromeric region  chromatin  DNA clamp loader activity  DNA clamp loader activity  protein binding  nucleoplasm  DNA replication  regulation of DNA replication  Ctf18 RFC-like complex  Ctf18 RFC-like complex  maintenance of mitotic sister chromatid cohesion  post-translational protein acetylation  single-stranded DNA-dependent ATPase activity  positive regulation of DNA-directed DNA polymerase activity  
NDEx NetworkDSCC1
Atlas of Cancer Signalling NetworkDSCC1
Wikipedia pathwaysDSCC1
Orthology - Evolution
OrthoDB79075
GeneTree (enSembl)ENSG00000136982
Phylogenetic Trees/Animal Genes : TreeFamDSCC1
HOVERGENQ9BVC3
HOGENOMQ9BVC3
Homologs : HomoloGeneDSCC1
Homology/Alignments : Family Browser (UCSC)DSCC1
Gene fusions - Rearrangements
Fusion : MitelmanTAF2/DSCC1 [8q24.12/8q24.12]  [t(8;8)(q24;q24)]  
Fusion: TCGATAF2 8q24.12 DSCC1 8q24.12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDSCC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DSCC1
dbVarDSCC1
ClinVarDSCC1
1000_GenomesDSCC1 
Exome Variant ServerDSCC1
ExAC (Exome Aggregation Consortium)DSCC1 (select the gene name)
Genetic variants : HAPMAP79075
Genomic Variants (DGV)DSCC1 [DGVbeta]
DECIPHER (Syndromes)8:120846181-120868170  ENSG00000136982
CONAN: Copy Number AnalysisDSCC1 
Mutations
ICGC Data PortalDSCC1 
TCGA Data PortalDSCC1 
Broad Tumor PortalDSCC1
OASIS PortalDSCC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDSCC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDSCC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DSCC1
DgiDB (Drug Gene Interaction Database)DSCC1
DoCM (Curated mutations)DSCC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DSCC1 (select a term)
intoGenDSCC1
Cancer3DDSCC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613203   
Orphanet
MedgenDSCC1
Genetic Testing Registry DSCC1
NextProtQ9BVC3 [Medical]
TSGene79075
GENETestsDSCC1
Huge Navigator DSCC1 [HugePedia]
snp3D : Map Gene to Disease79075
BioCentury BCIQDSCC1
ClinGenDSCC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79075
Chemical/Pharm GKB GenePA162384079
Clinical trialDSCC1
Miscellaneous
canSAR (ICR)DSCC1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDSCC1
EVEXDSCC1
GoPubMedDSCC1
iHOPDSCC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:59:24 CEST 2017

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