Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DSG1 (desmoglein 1)

Identity

Other namesCDHF4
DG1
DSG
EPKHE
EPKHIA
PPKS1
SPPK1
HGNC (Hugo) DSG1
LocusID (NCBI) 1828
Location 18q12.1
Location_base_pair Starts at 28898052 and ends at 28937393 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DSG1   3048
Cards
Entrez_Gene (NCBI)DSG1  1828  desmoglein 1
GeneCards (Weizmann)DSG1
Ensembl (Hinxton)ENSG00000134760 [Gene_View]  chr18:28898052-28937393 [Contig_View]  DSG1 [Vega]
ICGC DataPortalENSG00000134760
cBioPortalDSG1
AceView (NCBI)DSG1
Genatlas (Paris)DSG1
WikiGenes1828
SOURCE (Princeton)NM_001942
Genomic and cartography
GoldenPath (UCSC)DSG1  -  18q12.1   chr18:28898052-28937393 +  18q12.1   [Description]    (hg19-Feb_2009)
EnsemblDSG1 - 18q12.1 [CytoView]
Mapping of homologs : NCBIDSG1 [Mapview]
OMIM125670   148700   615508   
Gene and transcription
Genbank (Entrez)AF088042 AF097935 AK302888 BC148374 BC153001
RefSeq transcript (Entrez)NM_001942
RefSeq genomic (Entrez)AC_000150 NC_000018 NC_018929 NG_011803 NT_010966 NW_001838467 NW_004929410
Consensus coding sequences : CCDS (NCBI)DSG1
Cluster EST : UnigeneHs.2633 [ NCBI ]
CGAP (NCI)Hs.2633
Alternative Splicing : Fast-db (Paris)GSHG0013976
Alternative Splicing GalleryENSG00000134760
Gene ExpressionDSG1 [ NCBI-GEO ]     DSG1 [ SEEK ]   DSG1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02413 (Uniprot)
NextProtQ02413  [Medical]
With graphics : InterProQ02413
Splice isoforms : SwissVarQ02413 (Swissvar)
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin [organisation]   Cadherin-like [organisation]   Cadherin_CS [organisation]   Cadherin_cytoplasmic-dom [organisation]   Catenin_binding_dom [organisation]   Desmoglein [organisation]   Desmosomal_cadherin [organisation]  
Related proteins : CluSTrQ02413
Domain families : Pfam (Sanger)Cadherin (PF00028)    Cadherin_C (PF01049)   
Domain families : Pfam (NCBI)pfam00028    pfam01049   
Domain families : Smart (EMBL)CA (SM00112)  
DMDM Disease mutations1828
Blocks (Seattle)Q02413
Human Protein AtlasENSG00000134760 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ02413
HPRD00515
IPIIPI00025753   IPI00974353   
Protein Interaction databases
DIP (DOE-UCLA)Q02413
IntAct (EBI)Q02413
FunCoupENSG00000134760
BioGRIDDSG1
InParanoidQ02413
Interologous Interaction database Q02413
IntegromeDBDSG1
STRING (EMBL)DSG1
Ontologies - Pathways
Ontology : AmiGOcalcium ion binding  cytosol  plasma membrane  cell-cell junction  apoptotic process  cellular component disassembly involved in execution phase of apoptosis  cell-cell junction assembly  homophilic cell adhesion  cytoplasmic side of plasma membrane  toxic substance binding  integral component of membrane  apical plasma membrane  lateral plasma membrane  single organismal cell-cell adhesion  calcium-dependent cell-cell adhesion  desmosome  response to progesterone  gamma-catenin binding  protein stabilization  maternal process involved in female pregnancy  extracellular vesicular exosome  
Ontology : EGO-EBIcalcium ion binding  cytosol  plasma membrane  cell-cell junction  apoptotic process  cellular component disassembly involved in execution phase of apoptosis  cell-cell junction assembly  homophilic cell adhesion  cytoplasmic side of plasma membrane  toxic substance binding  integral component of membrane  apical plasma membrane  lateral plasma membrane  single organismal cell-cell adhesion  calcium-dependent cell-cell adhesion  desmosome  response to progesterone  gamma-catenin binding  protein stabilization  maternal process involved in female pregnancy  extracellular vesicular exosome  
Pathways : KEGGStaphylococcus aureus infection   
Protein Interaction DatabaseDSG1
Wikipedia pathwaysDSG1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)DSG1
snp3D : Map Gene to Disease1828
SNP (GeneSNP Utah)DSG1
SNP : HGBaseDSG1
Genetic variants : HAPMAPDSG1
Exome VariantDSG1
1000_GenomesDSG1 
ICGC programENSG00000134760 
Somatic Mutations in Cancer : COSMICDSG1 
CONAN: Copy Number AnalysisDSG1 
Mutations and Diseases : HGMDDSG1
Genomic VariantsDSG1  DSG1 [DGVbeta]
dbVarDSG1
ClinVarDSG1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM125670    148700    615508   
MedgenDSG1
GENETestsDSG1
Disease Genetic AssociationDSG1
Huge Navigator DSG1 [HugePedia]  DSG1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneDSG1
Homology/Alignments : Family Browser (UCSC)DSG1
Phylogenetic Trees/Animal Genes : TreeFamDSG1
Chemical/Protein Interactions : CTD1828
Chemical/Pharm GKB GenePA27501
Clinical trialDSG1
Cancer Resource (Charite)ENSG00000134760
Other databases
Probes
Litterature
PubMed77 Pubmed reference(s) in Entrez
CoreMineDSG1
iHOPDSG1
OncoSearchDSG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 13:52:04 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.