DTD1 (D-aminoacyl-tRNA deacylase 1)

2014-08-01  

Identity

HGNC
DTD1
LOCATION
20p11.23
LOCUSID
92675
ALIAS
C20orf88,DTD,DUE-B,DUEB,HARS2,pqn-68
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 92675
MIM: 610996
HGNC: 16219
Ensembl: ENSG00000125821

Variants:

dbSNP: 92675
ClinVar: 92675
TCGA: ENSG00000125821
COSMIC: DTD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125821ENST00000377452Q8TEA8
ENSG00000125821ENST00000494921A0A2R8Y6X2
ENSG00000125821ENST00000647441A0A2R8YCT7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
200650342010The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation.26
156536972005The c-myc DNA-unwinding element-binding protein modulates the assembly of DNA replication complexes in vitro.11
214793572011Association analysis of DTD1 gene variations with aspirin-intolerance in asthmatics.4
252583242014Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation.4
247724792014Identification and functional characterization of imatinib-sensitive DTD1-PDGFRB and CCDC88C-PDGFRB fusion genes in eosinophilia-associated myeloid/lymphoid neoplasms.3
123921682002Cloning and identification of a novel cDNA which may be associated with FKBP25.0
300379032018Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells.0

Citation

Dessen P

DTD1 (D-aminoacyl-tRNA deacylase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54267/dtd1