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DTD1 (D-tyrosyl-tRNA deacylase 1)

Identity

Alias_namesC20orf88
HARS2
chromosome 20 open reading frame 88
D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae)
Alias_symbol (synonym)DUEB
MGC119131
MGC41905
bA379J5.3
bA555E18.1
pqn-68
Other aliasDUE-B
HGNC (Hugo) DTD1
LocusID (NCBI) 92675
Atlas_Id 54267
Location 20p11.23  [Link to chromosome band 20p11]
Location_base_pair Starts at 18568537 and ends at 18612818 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AP1M2 (19p13.2) / DTD1 (20p11.23)COASY (17q21.2) / DTD1 (20p11.23)DSTN (20p12.1) / DTD1 (20p11.23)
DTD1 (20p11.23) / FKBP3 (14q21.2)DTD1 (20p11.23) / PDGFRB (5q32)DTD1 (20p11.23) / PET117 (20p11.23)
DTD1 (20p11.23) / RALGAPA2 (20p11.23)DZANK1 (20p11.23) / DTD1 (20p11.23)FRYL (4p11) / DTD1 (20p11.23)
LINC00493 (20p11.23) / DTD1 (20p11.23)PDGFRB (5q32) / DTD1 (20p11.23)C20orf12 DTD1 20p11.23
DSTN 20p12.1 / DTD1 20p11.23DTD1 20p11.23 / RALGAPA2 20p11.23FRYL 4p11 / DTD1 20p11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DTD1   16219
Cards
Entrez_Gene (NCBI)DTD1  92675  D-tyrosyl-tRNA deacylase 1
AliasesC20orf88; DUE-B; DUEB; HARS2; 
pqn-68
GeneCards (Weizmann)DTD1
Ensembl hg19 (Hinxton)ENSG00000125821 [Gene_View]  chr20:18568537-18612818 [Contig_View]  DTD1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000125821 [Gene_View]  chr20:18568537-18612818 [Contig_View]  DTD1 [Vega]
ICGC DataPortalENSG00000125821
TCGA cBioPortalDTD1
AceView (NCBI)DTD1
Genatlas (Paris)DTD1
WikiGenes92675
SOURCE (Princeton)DTD1
Genetics Home Reference (NIH)DTD1
Genomic and cartography
GoldenPath hg19 (UCSC)DTD1  -     chr20:18568537-18612818 +  20p11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DTD1  -     20p11.23   [Description]    (hg38-Dec_2013)
EnsemblDTD1 - 20p11.23 [CytoView hg19]  DTD1 - 20p11.23 [CytoView hg38]
Mapping of homologs : NCBIDTD1 [Mapview hg19]  DTD1 [Mapview hg38]
OMIM610996   
Gene and transcription
Genbank (Entrez)AF332356 AK074304 AK291440 AW022517 BC000599
RefSeq transcript (Entrez)NM_001318043 NM_080820
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011387 NW_004929416
Consensus coding sequences : CCDS (NCBI)DTD1
Cluster EST : UnigeneHs.659442 [ NCBI ]
CGAP (NCI)Hs.659442
Alternative Splicing GalleryENSG00000125821
Gene ExpressionDTD1 [ NCBI-GEO ]   DTD1 [ EBI - ARRAY_EXPRESS ]   DTD1 [ SEEK ]   DTD1 [ MEM ]
Gene Expression Viewer (FireBrowse)DTD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92675
GTEX Portal (Tissue expression)DTD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TEA8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TEA8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TEA8
Splice isoforms : SwissVarQ8TEA8
Catalytic activity : Enzyme3.1.-.- [ Enzyme-Expasy ]   3.1.-.-3.1.-.- [ IntEnz-EBI ]   3.1.-.- [ BRENDA ]   3.1.-.- [ KEGG ]   
PhosPhoSitePlusQ8TEA8
Domains : Interpro (EBI)Daa-tRNA_deacyls_DTD    DTD-like_dom   
Domain families : Pfam (Sanger)Tyr_Deacylase (PF02580)   
Domain families : Pfam (NCBI)pfam02580   
Conserved Domain (NCBI)DTD1
DMDM Disease mutations92675
Blocks (Seattle)DTD1
PDB (SRS)2OKV   
PDB (PDBSum)2OKV   
PDB (IMB)2OKV   
PDB (RSDB)2OKV   
Structural Biology KnowledgeBase2OKV   
SCOP (Structural Classification of Proteins)2OKV   
CATH (Classification of proteins structures)2OKV   
SuperfamilyQ8TEA8
Human Protein AtlasENSG00000125821
Peptide AtlasQ8TEA8
IPIIPI00152692   
Protein Interaction databases
DIP (DOE-UCLA)Q8TEA8
IntAct (EBI)Q8TEA8
FunCoupENSG00000125821
BioGRIDDTD1
STRING (EMBL)DTD1
ZODIACDTD1
Ontologies - Pathways
QuickGOQ8TEA8
Ontology : AmiGOaminoacyl-tRNA editing activity  DNA binding  nucleus  cytoplasm  DNA replication  tRNA metabolic process  regulation of translational fidelity  D-amino acid catabolic process  metal ion binding  D-tyrosyl-tRNA(Tyr) deacylase activity  
Ontology : EGO-EBIaminoacyl-tRNA editing activity  DNA binding  nucleus  cytoplasm  DNA replication  tRNA metabolic process  regulation of translational fidelity  D-amino acid catabolic process  metal ion binding  D-tyrosyl-tRNA(Tyr) deacylase activity  
NDEx NetworkDTD1
Atlas of Cancer Signalling NetworkDTD1
Wikipedia pathwaysDTD1
Orthology - Evolution
OrthoDB92675
GeneTree (enSembl)ENSG00000125821
Phylogenetic Trees/Animal Genes : TreeFamDTD1
HOVERGENQ8TEA8
HOGENOMQ8TEA8
Homologs : HomoloGeneDTD1
Homology/Alignments : Family Browser (UCSC)DTD1
Gene fusions - Rearrangements
Fusion : MitelmanDSTN/DTD1 [20p12.1/20p11.23]  [t(20;20)(p11;p12)]  
Fusion : MitelmanDTD1/PDGFRB [20p11.23/5q32]  [t(5;20)(q32;p11)]  
Fusion : MitelmanDTD1/RALGAPA2 [20p11.23/20p11.23]  [t(20;20)(p11;p11)]  
Fusion : MitelmanDZANK1/DTD1 [20p11.23/20p11.23]  [t(20;20)(p11;p11)]  
Fusion : MitelmanFRYL/DTD1 [4p11/20p11.23]  [t(4;20)(p12;p11)]  
Fusion : MitelmanPDGFRB/DTD1 [5q32/20p11.23]  [t(5;20)(q32;p11)]  
Fusion: TCGAC20orf12 DTD1 20p11.23 LUAD
Fusion: TCGADSTN 20p12.1 DTD1 20p11.23 PRAD
Fusion: TCGADTD1 20p11.23 RALGAPA2 20p11.23 HNSC
Fusion: TCGAFRYL 4p11 DTD1 20p11.23 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDTD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DTD1
dbVarDTD1
ClinVarDTD1
1000_GenomesDTD1 
Exome Variant ServerDTD1
ExAC (Exome Aggregation Consortium)DTD1 (select the gene name)
Genetic variants : HAPMAP92675
Genomic Variants (DGV)DTD1 [DGVbeta]
DECIPHER (Syndromes)20:18568537-18612818  ENSG00000125821
CONAN: Copy Number AnalysisDTD1 
Mutations
ICGC Data PortalDTD1 
TCGA Data PortalDTD1 
Broad Tumor PortalDTD1
OASIS PortalDTD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDTD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDTD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DTD1
DgiDB (Drug Gene Interaction Database)DTD1
DoCM (Curated mutations)DTD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DTD1 (select a term)
intoGenDTD1
Cancer3DDTD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610996   
Orphanet
MedgenDTD1
Genetic Testing Registry DTD1
NextProtQ8TEA8 [Medical]
TSGene92675
GENETestsDTD1
Huge Navigator DTD1 [HugePedia]
snp3D : Map Gene to Disease92675
BioCentury BCIQDTD1
ClinGenDTD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD92675
Chemical/Pharm GKB GenePA162384107
Clinical trialDTD1
Miscellaneous
canSAR (ICR)DTD1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDTD1
EVEXDTD1
GoPubMedDTD1
iHOPDTD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:03:56 CET 2017

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