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DTNA (dystrobrevin, alpha)

Identity

Alias_namesdystrobrevin, alpha
Alias_symbol (synonym)D18S892E
DTN
DTN-1
DTN-2
DTN-3
DRP3
Other aliasDTN-A
LVNC1
HGNC (Hugo) DTNA
LocusID (NCBI) 1837
Atlas_Id 62664
Location 18q12.1  [Link to chromosome band 18q12]
Location_base_pair Starts at 32173282 and ends at 32409292 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DPP6 (7q36.2) / DTNA (18q12.1)DTNA (18q12.1) / DTNA (18q12.1)DTNA (18q12.1) / GABARAPL1 (12p13.2)
DTNA (18q12.1) / RPRD1A (18q12.2)DTNA (18q12.1) / ZNF521 (18q11.2)SNRPN (15q11.2) / DTNA (18q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DTNA   3057
LRG (Locus Reference Genomic)LRG_756
Cards
Entrez_Gene (NCBI)DTNA  1837  dystrobrevin, alpha
AliasesD18S892E; DRP3; DTN; DTN-A; 
LVNC1
GeneCards (Weizmann)DTNA
Ensembl hg19 (Hinxton)ENSG00000134769 [Gene_View]  chr18:32173282-32409292 [Contig_View]  DTNA [Vega]
Ensembl hg38 (Hinxton)ENSG00000134769 [Gene_View]  chr18:32173282-32409292 [Contig_View]  DTNA [Vega]
ICGC DataPortalENSG00000134769
TCGA cBioPortalDTNA
AceView (NCBI)DTNA
Genatlas (Paris)DTNA
WikiGenes1837
SOURCE (Princeton)DTNA
Genetics Home Reference (NIH)DTNA
Genomic and cartography
GoldenPath hg19 (UCSC)DTNA  -     chr18:32173282-32409292 +  18q12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DTNA  -     18q12.1   [Description]    (hg38-Dec_2013)
EnsemblDTNA - 18q12.1 [CytoView hg19]  DTNA - 18q12.1 [CytoView hg38]
Mapping of homologs : NCBIDTNA [Mapview hg19]  DTNA [Mapview hg38]
OMIM601239   604169   
Gene and transcription
Genbank (Entrez)AB209102 AI368045 AI670964 AJ009668 AK054766
RefSeq transcript (Entrez)NM_001128175 NM_001198938 NM_001198939 NM_001198940 NM_001198941 NM_001198942 NM_001198943 NM_001198944 NM_001198945 NM_001390 NM_001391 NM_001392 NM_032975 NM_032978 NM_032979 NM_032980 NM_032981
RefSeq genomic (Entrez)NC_000018 NC_018929 NG_009201 NT_010966 NW_004929410
Consensus coding sequences : CCDS (NCBI)DTNA
Cluster EST : UnigeneHs.643454 [ NCBI ]
CGAP (NCI)Hs.643454
Alternative Splicing GalleryENSG00000134769
Gene ExpressionDTNA [ NCBI-GEO ]   DTNA [ EBI - ARRAY_EXPRESS ]   DTNA [ SEEK ]   DTNA [ MEM ]
Gene Expression Viewer (FireBrowse)DTNA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1837
GTEX Portal (Tissue expression)DTNA
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4J8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4J8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4J8
Splice isoforms : SwissVarQ9Y4J8
PhosPhoSitePlusQ9Y4J8
Domaine pattern : Prosite (Expaxy)ZF_ZZ_1 (PS01357)    ZF_ZZ_2 (PS50135)   
Domains : Interpro (EBI)Distrobrevin    EF-hand-dom_pair    EF-hand_dom_typ1    EF-hand_dom_typ2    Znf_ZZ   
Domain families : Pfam (Sanger)EF-hand_2 (PF09068)    EF-hand_3 (PF09069)    ZZ (PF00569)   
Domain families : Pfam (NCBI)pfam09068    pfam09069    pfam00569   
Domain families : Smart (EMBL)ZnF_ZZ (SM00291)  
Conserved Domain (NCBI)DTNA
DMDM Disease mutations1837
Blocks (Seattle)DTNA
PDB (SRS)2E5R   
PDB (PDBSum)2E5R   
PDB (IMB)2E5R   
PDB (RSDB)2E5R   
Structural Biology KnowledgeBase2E5R   
SCOP (Structural Classification of Proteins)2E5R   
CATH (Classification of proteins structures)2E5R   
SuperfamilyQ9Y4J8
Human Protein AtlasENSG00000134769
Peptide AtlasQ9Y4J8
HPRD03141
IPIIPI00942739   IPI00929645   IPI00749235   IPI00218653   IPI00296091   IPI00177936   IPI00402365   IPI00218655   IPI00976991   IPI00000845   IPI01026550   IPI00938014   IPI00910552   IPI01014048   IPI00976002   IPI00985310   IPI00911079   IPI00981435   IPI00908852   IPI00793449   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4J8
IntAct (EBI)Q9Y4J8
FunCoupENSG00000134769
BioGRIDDTNA
STRING (EMBL)DTNA
ZODIACDTNA
Ontologies - Pathways
QuickGOQ9Y4J8
Ontology : AmiGOprotein binding  cytoplasm  striated muscle contraction  signal transduction  synaptic transmission  neuromuscular synaptic transmission  zinc ion binding  cell junction  PDZ domain binding  axon  extrinsic component of cytoplasmic side of plasma membrane  sarcolemma  protein complex  synapse  
Ontology : EGO-EBIprotein binding  cytoplasm  striated muscle contraction  signal transduction  synaptic transmission  neuromuscular synaptic transmission  zinc ion binding  cell junction  PDZ domain binding  axon  extrinsic component of cytoplasmic side of plasma membrane  sarcolemma  protein complex  synapse  
NDEx NetworkDTNA
Atlas of Cancer Signalling NetworkDTNA
Wikipedia pathwaysDTNA
Orthology - Evolution
OrthoDB1837
GeneTree (enSembl)ENSG00000134769
Phylogenetic Trees/Animal Genes : TreeFamDTNA
HOVERGENQ9Y4J8
HOGENOMQ9Y4J8
Homologs : HomoloGeneDTNA
Homology/Alignments : Family Browser (UCSC)DTNA
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDTNA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DTNA
dbVarDTNA
ClinVarDTNA
1000_GenomesDTNA 
Exome Variant ServerDTNA
ExAC (Exome Aggregation Consortium)DTNA (select the gene name)
Genetic variants : HAPMAP1837
Genomic Variants (DGV)DTNA [DGVbeta]
DECIPHER (Syndromes)18:32173282-32409292  ENSG00000134769
CONAN: Copy Number AnalysisDTNA 
Mutations
ICGC Data PortalDTNA 
TCGA Data PortalDTNA 
Broad Tumor PortalDTNA
OASIS PortalDTNA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDTNA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDTNA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)Leiden Muscular Dystrophy pages
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DTNA
DgiDB (Drug Gene Interaction Database)DTNA
DoCM (Curated mutations)DTNA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DTNA (select a term)
intoGenDTNA
Cancer3DDTNA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601239    604169   
Orphanet10750   
MedgenDTNA
Genetic Testing Registry DTNA
NextProtQ9Y4J8 [Medical]
TSGene1837
GENETestsDTNA
Huge Navigator DTNA [HugePedia]
snp3D : Map Gene to Disease1837
BioCentury BCIQDTNA
ClinGenDTNA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1837
Chemical/Pharm GKB GenePA27510
Clinical trialDTNA
Miscellaneous
canSAR (ICR)DTNA (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDTNA
EVEXDTNA
GoPubMedDTNA
iHOPDTNA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:02:19 CET 2017

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