Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DTX3L (deltex E3 ubiquitin ligase 3L)

Identity

Alias_namesdeltex 3-like (Drosophila)
Alias_symbol (synonym)BBAP
Other alias
HGNC (Hugo) DTX3L
LocusID (NCBI) 151636
Atlas_Id 50567
Location 3q21.1  [Link to chromosome band 3q21]
Location_base_pair Starts at 122564338 and ends at 122575202 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DTX3L (3q21.1) / DTX3L (3q21.1)DTX3L (3q21.1) / HLA-DRB5 (6p21.32)DTX3L (3q21.1) / NFXL1 (4p12)
HLA-DRB5 (6p21.32) / DTX3L (3q21.1)NFATC2 (20q13.2) / DTX3L (3q21.1)POLR2H (3q27.1) / DTX3L (3q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DTX3L   30323
Cards
Entrez_Gene (NCBI)DTX3L  151636  deltex E3 ubiquitin ligase 3L
AliasesBBAP
GeneCards (Weizmann)DTX3L
Ensembl hg19 (Hinxton)ENSG00000163840 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163840 [Gene_View]  chr3:122564338-122575202 [Contig_View]  DTX3L [Vega]
ICGC DataPortalENSG00000163840
TCGA cBioPortalDTX3L
AceView (NCBI)DTX3L
Genatlas (Paris)DTX3L
WikiGenes151636
SOURCE (Princeton)DTX3L
Genetics Home Reference (NIH)DTX3L
Genomic and cartography
GoldenPath hg38 (UCSC)DTX3L  -     chr3:122564338-122575202 +  3q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DTX3L  -     3q21.1   [Description]    (hg19-Feb_2009)
EnsemblDTX3L - 3q21.1 [CytoView hg19]  DTX3L - 3q21.1 [CytoView hg38]
Mapping of homologs : NCBIDTX3L [Mapview hg19]  DTX3L [Mapview hg38]
OMIM613143   
Gene and transcription
Genbank (Entrez)AF484416 AK025135 AK056406 AK093782 AK125086
RefSeq transcript (Entrez)NM_138287
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DTX3L
Cluster EST : UnigeneHs.518201 [ NCBI ]
CGAP (NCI)Hs.518201
Alternative Splicing GalleryENSG00000163840
Gene ExpressionDTX3L [ NCBI-GEO ]   DTX3L [ EBI - ARRAY_EXPRESS ]   DTX3L [ SEEK ]   DTX3L [ MEM ]
Gene Expression Viewer (FireBrowse)DTX3L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)151636
GTEX Portal (Tissue expression)DTX3L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TDB6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TDB6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TDB6
Splice isoforms : SwissVarQ8TDB6
PhosPhoSitePlusQ8TDB6
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)DTX3L
DMDM Disease mutations151636
Blocks (Seattle)DTX3L
PDB (SRS)3PG6   
PDB (PDBSum)3PG6   
PDB (IMB)3PG6   
PDB (RSDB)3PG6   
Structural Biology KnowledgeBase3PG6   
SCOP (Structural Classification of Proteins)3PG6   
CATH (Classification of proteins structures)3PG6   
SuperfamilyQ8TDB6
Human Protein AtlasENSG00000163840
Peptide AtlasQ8TDB6
HPRD16843
IPIIPI00152503   IPI00549221   
Protein Interaction databases
DIP (DOE-UCLA)Q8TDB6
IntAct (EBI)Q8TDB6
FunCoupENSG00000163840
BioGRIDDTX3L
STRING (EMBL)DTX3L
ZODIACDTX3L
Ontologies - Pathways
QuickGOQ8TDB6
Ontology : AmiGOprotein polyubiquitination  RNA binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  double-strand break repair  cellular response to DNA damage stimulus  zinc ion binding  histone monoubiquitination  histone binding  
Ontology : EGO-EBIprotein polyubiquitination  RNA binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  double-strand break repair  cellular response to DNA damage stimulus  zinc ion binding  histone monoubiquitination  histone binding  
Pathways : KEGGNotch signaling pathway   
NDEx NetworkDTX3L
Atlas of Cancer Signalling NetworkDTX3L
Wikipedia pathwaysDTX3L
Orthology - Evolution
OrthoDB151636
GeneTree (enSembl)ENSG00000163840
Phylogenetic Trees/Animal Genes : TreeFamDTX3L
HOVERGENQ8TDB6
HOGENOMQ8TDB6
Homologs : HomoloGeneDTX3L
Homology/Alignments : Family Browser (UCSC)DTX3L
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDTX3L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DTX3L
dbVarDTX3L
ClinVarDTX3L
1000_GenomesDTX3L 
Exome Variant ServerDTX3L
ExAC (Exome Aggregation Consortium)DTX3L (select the gene name)
Genetic variants : HAPMAP151636
Genomic Variants (DGV)DTX3L [DGVbeta]
DECIPHERDTX3L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDTX3L 
Mutations
ICGC Data PortalDTX3L 
TCGA Data PortalDTX3L 
Broad Tumor PortalDTX3L
OASIS PortalDTX3L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDTX3L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDTX3L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DTX3L
DgiDB (Drug Gene Interaction Database)DTX3L
DoCM (Curated mutations)DTX3L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DTX3L (select a term)
intoGenDTX3L
Cancer3DDTX3L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613143   
Orphanet
MedgenDTX3L
Genetic Testing Registry DTX3L
NextProtQ8TDB6 [Medical]
TSGene151636
GENETestsDTX3L
Huge Navigator DTX3L [HugePedia]
snp3D : Map Gene to Disease151636
BioCentury BCIQDTX3L
ClinGenDTX3L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD151636
Chemical/Pharm GKB GenePA134864792
Clinical trialDTX3L
Miscellaneous
canSAR (ICR)DTX3L (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDTX3L
EVEXDTX3L
GoPubMedDTX3L
iHOPDTX3L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:13:57 CEST 2017

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