Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DTX4 (deltex E3 ubiquitin ligase 4)

Identity

Alias (NCBI)RNF155
HGNC (Hugo) DTX4
HGNC Alias symbKIAA0937
RNF155
HGNC Previous namedeltex homolog 4 (Drosophila)
LocusID (NCBI) 23220
Atlas_Id 62669
Location 11q12.1  [Link to chromosome band 11q12]
Location_base_pair Starts at 59172132 and ends at 59208588 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DTX4 (11q12.1)::CCDC102B (18q22.1)FCHSD2 (11q13.4)::DTX4 (11q12.1)MRPL48 (11q13.4)::DTX4 (11q12.1)
TMEM91 (19q13.2)::DTX4 (11q12.1)MRPL48 DTX4FCHSD2 DTX4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)DTX4   29151
Cards
Entrez_Gene (NCBI)DTX4    deltex E3 ubiquitin ligase 4
AliasesRNF155
GeneCards (Weizmann)DTX4
Ensembl hg19 (Hinxton)ENSG00000110042 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110042 [Gene_View]  ENSG00000110042 [Sequence]  chr11:59172132-59208588 [Contig_View]  DTX4 [Vega]
ICGC DataPortalENSG00000110042
TCGA cBioPortalDTX4
AceView (NCBI)DTX4
Genatlas (Paris)DTX4
SOURCE (Princeton)DTX4
Genetics Home Reference (NIH)DTX4
Genomic and cartography
GoldenPath hg38 (UCSC)DTX4  -     chr11:59172132-59208588 +  11q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DTX4  -     11q12.1   [Description]    (hg19-Feb_2009)
GoldenPathDTX4 - 11q12.1 [CytoView hg19]  DTX4 - 11q12.1 [CytoView hg38]
ImmunoBaseENSG00000110042
Genome Data Viewer NCBIDTX4 [Mapview hg19]  
OMIM616110   
Gene and transcription
Genbank (Entrez)AB023154 AF086290 BC015592 BC119011 BC122861
RefSeq transcript (Entrez)NM_001300727 NM_015177
Consensus coding sequences : CCDS (NCBI)DTX4
Gene ExpressionDTX4 [ NCBI-GEO ]   DTX4 [ EBI - ARRAY_EXPRESS ]   DTX4 [ SEEK ]   DTX4 [ MEM ]
Gene Expression Viewer (FireBrowse)DTX4 [ Firebrowse - Broad ]
GenevisibleExpression of DTX4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23220
GTEX Portal (Tissue expression)DTX4
Human Protein AtlasENSG00000110042-DTX4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2E6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2E6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2E6
PhosPhoSitePlusQ9Y2E6
Domaine pattern : Prosite (Expaxy)WWE (PS50918)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Deltex_C    Deltex_C_sf    Deltex_fam    WWE-dom    WWE-dom_subgr    WWE_dom_sf    Znf_C3HC4_RING-type    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)DTC (PF18102)    WWE (PF02825)    zf-C3HC4 (PF00097)   
Domain families : Pfam (NCBI)pfam18102    pfam02825    pfam00097   
Domain families : Smart (EMBL)RING (SM00184)  WWE (SM00678)  
Conserved Domain (NCBI)DTX4
SuperfamilyQ9Y2E6
AlphaFold pdb e-kbQ9Y2E6   
Human Protein Atlas [tissue]ENSG00000110042-DTX4 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2E6
IntAct (EBI)Q9Y2E6
BioGRIDDTX4
STRING (EMBL)DTX4
ZODIACDTX4
Ontologies - Pathways
QuickGOQ9Y2E6
Ontology : AmiGOnucleoplasm  cytosol  Notch signaling pathway  zinc ion binding  protein ubiquitination  protein ubiquitination  regulation of type I interferon production  ubiquitin protein ligase activity  
Ontology : EGO-EBInucleoplasm  cytosol  Notch signaling pathway  zinc ion binding  protein ubiquitination  protein ubiquitination  regulation of type I interferon production  ubiquitin protein ligase activity  
Pathways : KEGGKEGG_hsa04330 Notch signaling pathway   
NDEx NetworkDTX4
Atlas of Cancer Signalling NetworkDTX4
Wikipedia pathwaysDTX4
Orthology - Evolution
OrthoDB23220
GeneTree (enSembl)ENSG00000110042
Phylogenetic Trees/Animal Genes : TreeFamDTX4
Homologs : HomoloGeneDTX4
Homology/Alignments : Family Browser (UCSC)DTX4
Gene fusions - Rearrangements
Fusion : QuiverDTX4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDTX4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DTX4
dbVarDTX4
ClinVarDTX4
MonarchDTX4
1000_GenomesDTX4 
Exome Variant ServerDTX4
GNOMAD BrowserENSG00000110042
Varsome BrowserDTX4
ACMGDTX4 variants
VarityQ9Y2E6
Genomic Variants (DGV)DTX4 [DGVbeta]
DECIPHERDTX4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDTX4 
Mutations
ICGC Data PortalDTX4 
TCGA Data PortalDTX4 
Broad Tumor PortalDTX4
OASIS PortalDTX4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDTX4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDTX4
Mutations and Diseases : HGMDDTX4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDTX4
DgiDB (Drug Gene Interaction Database)DTX4
DoCM (Curated mutations)DTX4
CIViC (Clinical Interpretations of Variants in Cancer)DTX4
Cancer3DDTX4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616110   
Orphanet
DisGeNETDTX4
MedgenDTX4
Genetic Testing Registry DTX4
NextProtQ9Y2E6 [Medical]
GENETestsDTX4
Target ValidationDTX4
Huge Navigator DTX4 [HugePedia]
ClinGenDTX4
Clinical trials, drugs, therapy
MyCancerGenomeDTX4
Protein Interactions : CTDDTX4
Pharm GKB GenePA134930720
PharosQ9Y2E6
Clinical trialDTX4
Miscellaneous
canSAR (ICR)DTX4
HarmonizomeDTX4
ARCHS4DTX4
DataMed IndexDTX4
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDTX4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 20 13:17:19 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.