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DUSP11 (dual specificity phosphatase 11)

Identity

Alias_namesdual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
Alias_symbol (synonym)PIR1
Other alias
HGNC (Hugo) DUSP11
LocusID (NCBI) 8446
Atlas_Id 56384
Location 2p13.1  [Link to chromosome band 2p13]
Location_base_pair Starts at 73762198 and ends at 73780157 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DUSP11 (2p13.1) / DUSP11 (2p13.1)DUSP11 (2p13.1) / RMND5A (2p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DUSP11   3066
Cards
Entrez_Gene (NCBI)DUSP11  8446  dual specificity phosphatase 11
AliasesPIR1
GeneCards (Weizmann)DUSP11
Ensembl hg19 (Hinxton)ENSG00000144048 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144048 [Gene_View]  chr2:73762198-73780157 [Contig_View]  DUSP11 [Vega]
ICGC DataPortalENSG00000144048
TCGA cBioPortalDUSP11
AceView (NCBI)DUSP11
Genatlas (Paris)DUSP11
WikiGenes8446
SOURCE (Princeton)DUSP11
Genetics Home Reference (NIH)DUSP11
Genomic and cartography
GoldenPath hg38 (UCSC)DUSP11  -     chr2:73762198-73780157 -  2p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DUSP11  -     2p13.1   [Description]    (hg19-Feb_2009)
EnsemblDUSP11 - 2p13.1 [CytoView hg19]  DUSP11 - 2p13.1 [CytoView hg38]
Mapping of homologs : NCBIDUSP11 [Mapview hg19]  DUSP11 [Mapview hg38]
OMIM603092   
Gene and transcription
Genbank (Entrez)AF023917 AK315271 BC000346 BP349009 BP359552
RefSeq transcript (Entrez)NM_003584
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DUSP11
Cluster EST : UnigeneHs.14611 [ NCBI ]
CGAP (NCI)Hs.14611
Alternative Splicing GalleryENSG00000144048
Gene ExpressionDUSP11 [ NCBI-GEO ]   DUSP11 [ EBI - ARRAY_EXPRESS ]   DUSP11 [ SEEK ]   DUSP11 [ MEM ]
Gene Expression Viewer (FireBrowse)DUSP11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8446
GTEX Portal (Tissue expression)DUSP11
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75319   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75319  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75319
Splice isoforms : SwissVarO75319
Catalytic activity : Enzyme3.1.3.- [ Enzyme-Expasy ]   3.1.3.-3.1.3.- [ IntEnz-EBI ]   3.1.3.- [ BRENDA ]   3.1.3.- [ KEGG ]   
PhosPhoSitePlusO75319
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)   
Domains : Interpro (EBI)Dual-sp_phosphatase_cat-dom    Prot-tyrosine_phosphatase-like    Tyr_Pase_AS    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DSPc (PF00782)   
Domain families : Pfam (NCBI)pfam00782   
Domain families : Smart (EMBL)DSPc (SM00195)  
Conserved Domain (NCBI)DUSP11
DMDM Disease mutations8446
Blocks (Seattle)DUSP11
PDB (SRS)4JMJ    4MBB    4NYH   
PDB (PDBSum)4JMJ    4MBB    4NYH   
PDB (IMB)4JMJ    4MBB    4NYH   
PDB (RSDB)4JMJ    4MBB    4NYH   
Structural Biology KnowledgeBase4JMJ    4MBB    4NYH   
SCOP (Structural Classification of Proteins)4JMJ    4MBB    4NYH   
CATH (Classification of proteins structures)4JMJ    4MBB    4NYH   
SuperfamilyO75319
Human Protein AtlasENSG00000144048
Peptide AtlasO75319
HPRD04368
IPIIPI00020683   IPI00465012   IPI00925927   
Protein Interaction databases
DIP (DOE-UCLA)O75319
IntAct (EBI)O75319
FunCoupENSG00000144048
BioGRIDDUSP11
STRING (EMBL)DUSP11
ZODIACDUSP11
Ontologies - Pathways
QuickGOO75319
Ontology : AmiGOfibrillar center  RNA binding  polynucleotide 5'-phosphatase activity  protein tyrosine phosphatase activity  nucleus  RNA processing  protein dephosphorylation  protein tyrosine/serine/threonine phosphatase activity  RNA metabolic process  nuclear speck  phosphatase activity  peptidyl-tyrosine dephosphorylation  intercellular bridge  polynucleotide 5' dephosphorylation  nucleotide phosphatase activity, acting on free nucleotides  
Ontology : EGO-EBIfibrillar center  RNA binding  polynucleotide 5'-phosphatase activity  protein tyrosine phosphatase activity  nucleus  RNA processing  protein dephosphorylation  protein tyrosine/serine/threonine phosphatase activity  RNA metabolic process  nuclear speck  phosphatase activity  peptidyl-tyrosine dephosphorylation  intercellular bridge  polynucleotide 5' dephosphorylation  nucleotide phosphatase activity, acting on free nucleotides  
NDEx NetworkDUSP11
Atlas of Cancer Signalling NetworkDUSP11
Wikipedia pathwaysDUSP11
Orthology - Evolution
OrthoDB8446
GeneTree (enSembl)ENSG00000144048
Phylogenetic Trees/Animal Genes : TreeFamDUSP11
HOVERGENO75319
HOGENOMO75319
Homologs : HomoloGeneDUSP11
Homology/Alignments : Family Browser (UCSC)DUSP11
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDUSP11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DUSP11
dbVarDUSP11
ClinVarDUSP11
1000_GenomesDUSP11 
Exome Variant ServerDUSP11
ExAC (Exome Aggregation Consortium)DUSP11 (select the gene name)
Genetic variants : HAPMAP8446
Genomic Variants (DGV)DUSP11 [DGVbeta]
DECIPHERDUSP11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDUSP11 
Mutations
ICGC Data PortalDUSP11 
TCGA Data PortalDUSP11 
Broad Tumor PortalDUSP11
OASIS PortalDUSP11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDUSP11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDUSP11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DUSP11
DgiDB (Drug Gene Interaction Database)DUSP11
DoCM (Curated mutations)DUSP11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DUSP11 (select a term)
intoGenDUSP11
Cancer3DDUSP11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603092   
Orphanet
MedgenDUSP11
Genetic Testing Registry DUSP11
NextProtO75319 [Medical]
TSGene8446
GENETestsDUSP11
Target ValidationDUSP11
Huge Navigator DUSP11 [HugePedia]
snp3D : Map Gene to Disease8446
BioCentury BCIQDUSP11
ClinGenDUSP11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8446
Chemical/Pharm GKB GenePA27521
Clinical trialDUSP11
Miscellaneous
canSAR (ICR)DUSP11 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDUSP11
EVEXDUSP11
GoPubMedDUSP11
iHOPDUSP11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:59:59 CEST 2017

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