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DUSP12 (dual specificity phosphatase 12)

Identity

Alias_symbol (synonym)YVH1
DUSP1
Other alias
HGNC (Hugo) DUSP12
LocusID (NCBI) 11266
Atlas_Id 62674
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 161749768 and ends at 161757164 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DUSP12 (1q23.3) / CR2 (1q32.2)DUSP12 (1q23.3) / NAV1 (1q32.1)DUSP12 NAV1
DUSP12 CR2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(1;1)(q23;q32) DUSP12/NAV1
t(1;1)(q23;q32) DUSP12/CR2

External links

Nomenclature
HGNC (Hugo)DUSP12   3067
Cards
Entrez_Gene (NCBI)DUSP12  11266  dual specificity phosphatase 12
AliasesDUSP1; YVH1
GeneCards (Weizmann)DUSP12
Ensembl hg19 (Hinxton)ENSG00000081721 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000081721 [Gene_View]  ENSG00000081721 [Sequence]  chr1:161749768-161757164 [Contig_View]  DUSP12 [Vega]
ICGC DataPortalENSG00000081721
TCGA cBioPortalDUSP12
AceView (NCBI)DUSP12
Genatlas (Paris)DUSP12
WikiGenes11266
SOURCE (Princeton)DUSP12
Genetics Home Reference (NIH)DUSP12
Genomic and cartography
GoldenPath hg38 (UCSC)DUSP12  -     chr1:161749768-161757164 +  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DUSP12  -     1q23.3   [Description]    (hg19-Feb_2009)
EnsemblDUSP12 - 1q23.3 [CytoView hg19]  DUSP12 - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBIDUSP12 [Mapview hg19]  DUSP12 [Mapview hg38]
OMIM604835   
Gene and transcription
Genbank (Entrez)AF119226 AK000259 AW511560 BC006286 BT006633
RefSeq transcript (Entrez)NM_007240
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DUSP12
Cluster EST : UnigeneHs.416216 [ NCBI ]
CGAP (NCI)Hs.416216
Alternative Splicing GalleryENSG00000081721
Gene ExpressionDUSP12 [ NCBI-GEO ]   DUSP12 [ EBI - ARRAY_EXPRESS ]   DUSP12 [ SEEK ]   DUSP12 [ MEM ]
Gene Expression Viewer (FireBrowse)DUSP12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11266
GTEX Portal (Tissue expression)DUSP12
Human Protein AtlasENSG00000081721-DUSP12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UNI6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UNI6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UNI6
Splice isoforms : SwissVarQ9UNI6
PhosPhoSitePlusQ9UNI6
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Dual-sp_phosphatase_cat-dom    DUSP    DUSP12    Prot-tyrosine_phosphatase-like    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom    Znf_C2H2   
Domain families : Pfam (Sanger)DSPc (PF00782)   
Domain families : Pfam (NCBI)pfam00782   
Domain families : Smart (EMBL)DSPc (SM00195)  
Conserved Domain (NCBI)DUSP12
DMDM Disease mutations11266
Blocks (Seattle)DUSP12
PDB (SRS)4JNB    4KI9   
PDB (PDBSum)4JNB    4KI9   
PDB (IMB)4JNB    4KI9   
PDB (RSDB)4JNB    4KI9   
Structural Biology KnowledgeBase4JNB    4KI9   
SCOP (Structural Classification of Proteins)4JNB    4KI9   
CATH (Classification of proteins structures)4JNB    4KI9   
SuperfamilyQ9UNI6
Human Protein Atlas [tissue]ENSG00000081721-DUSP12 [tissue]
Peptide AtlasQ9UNI6
HPRD05323
IPIIPI00009210   
Protein Interaction databases
DIP (DOE-UCLA)Q9UNI6
IntAct (EBI)Q9UNI6
FunCoupENSG00000081721
BioGRIDDUSP12
STRING (EMBL)DUSP12
ZODIACDUSP12
Ontologies - Pathways
QuickGOQ9UNI6
Ontology : AmiGO###############################################################################################################################################################################################################################################################                            
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################                            
NDEx NetworkDUSP12
Atlas of Cancer Signalling NetworkDUSP12
Wikipedia pathwaysDUSP12
Orthology - Evolution
OrthoDB11266
GeneTree (enSembl)ENSG00000081721
Phylogenetic Trees/Animal Genes : TreeFamDUSP12
HOVERGENQ9UNI6
HOGENOMQ9UNI6
Homologs : HomoloGeneDUSP12
Homology/Alignments : Family Browser (UCSC)DUSP12
Gene fusions - Rearrangements
Fusion PortalDUSP12 NAV1
Fusion PortalDUSP12 CR2
Fusion : QuiverDUSP12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDUSP12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DUSP12
dbVarDUSP12
ClinVarDUSP12
1000_GenomesDUSP12 
Exome Variant ServerDUSP12
ExAC (Exome Aggregation Consortium)ENSG00000081721
GNOMAD BrowserENSG00000081721
Varsome BrowserDUSP12
Genetic variants : HAPMAP11266
Genomic Variants (DGV)DUSP12 [DGVbeta]
DECIPHERDUSP12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDUSP12 
Mutations
ICGC Data PortalDUSP12 
TCGA Data PortalDUSP12 
Broad Tumor PortalDUSP12
OASIS PortalDUSP12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDUSP12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDUSP12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DUSP12
DgiDB (Drug Gene Interaction Database)DUSP12
DoCM (Curated mutations)DUSP12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DUSP12 (select a term)
intoGenDUSP12
Cancer3DDUSP12(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604835   
Orphanet
DisGeNETDUSP12
MedgenDUSP12
Genetic Testing Registry DUSP12
NextProtQ9UNI6 [Medical]
TSGene11266
GENETestsDUSP12
Target ValidationDUSP12
Huge Navigator DUSP12 [HugePedia]
snp3D : Map Gene to Disease11266
BioCentury BCIQDUSP12
ClinGenDUSP12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11266
Chemical/Pharm GKB GenePA27522
Clinical trialDUSP12
Miscellaneous
canSAR (ICR)DUSP12 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDUSP12
EVEXDUSP12
GoPubMedDUSP12
iHOPDUSP12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:43:24 CEST 2018
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