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DUSP12 (dual specificity phosphatase 12)

Identity

Alias (NCBI)DUSP1
YVH1
HGNC (Hugo) DUSP12
HGNC Alias symbYVH1
DUSP1
HGNC Alias nameserine/threonine specific protein phosphatase
 YVH1 protein-tyrosine phosphatase (S. cerevisiae) ortholog
LocusID (NCBI) 11266
Atlas_Id 62674
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 161749786 and ends at 161757238 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DUSP12 (1q23.3) / CR2 (1q32.2)DUSP12 (1q23.3) / NAV1 (1q32.1)DUSP12 NAV1
DUSP12 CR2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)DUSP12   3067
Cards
Entrez_Gene (NCBI)DUSP12    dual specificity phosphatase 12
AliasesDUSP1; YVH1
GeneCards (Weizmann)DUSP12
Ensembl hg19 (Hinxton)ENSG00000081721 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000081721 [Gene_View]  ENSG00000081721 [Sequence]  chr1:161749786-161757238 [Contig_View]  DUSP12 [Vega]
ICGC DataPortalENSG00000081721
TCGA cBioPortalDUSP12
AceView (NCBI)DUSP12
Genatlas (Paris)DUSP12
SOURCE (Princeton)DUSP12
Genetics Home Reference (NIH)DUSP12
Genomic and cartography
GoldenPath hg38 (UCSC)DUSP12  -     chr1:161749786-161757238 +  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DUSP12  -     1q23.3   [Description]    (hg19-Feb_2009)
GoldenPathDUSP12 - 1q23.3 [CytoView hg19]  DUSP12 - 1q23.3 [CytoView hg38]
ImmunoBaseENSG00000081721
Genome Data Viewer NCBIDUSP12 [Mapview hg19]  
OMIM604835   
Gene and transcription
Genbank (Entrez)AF119226 AK000259 AW511560 BC006286 BT006633
RefSeq transcript (Entrez)NM_007240
Consensus coding sequences : CCDS (NCBI)DUSP12
Gene ExpressionDUSP12 [ NCBI-GEO ]   DUSP12 [ EBI - ARRAY_EXPRESS ]   DUSP12 [ SEEK ]   DUSP12 [ MEM ]
Gene Expression Viewer (FireBrowse)DUSP12 [ Firebrowse - Broad ]
GenevisibleExpression of DUSP12 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11266
GTEX Portal (Tissue expression)DUSP12
Human Protein AtlasENSG00000081721-DUSP12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UNI6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UNI6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UNI6
PhosPhoSitePlusQ9UNI6
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Dual-sp_phosphatase_cat-dom    DUSP12    Prot-tyrosine_phosphatase-like    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom    Znf_C2H2_type   
Domain families : Pfam (Sanger)DSPc (PF00782)   
Domain families : Pfam (NCBI)pfam00782   
Domain families : Smart (EMBL)DSPc (SM00195)  
Conserved Domain (NCBI)DUSP12
PDB (RSDB)4JNB    4KI9   
PDB Europe4JNB    4KI9   
PDB (PDBSum)4JNB    4KI9   
PDB (IMB)4JNB    4KI9   
Structural Biology KnowledgeBase4JNB    4KI9   
SCOP (Structural Classification of Proteins)4JNB    4KI9   
CATH (Classification of proteins structures)4JNB    4KI9   
SuperfamilyQ9UNI6
AlphaFold pdb e-kbQ9UNI6   
Human Protein Atlas [tissue]ENSG00000081721-DUSP12 [tissue]
HPRD05323
Protein Interaction databases
DIP (DOE-UCLA)Q9UNI6
IntAct (EBI)Q9UNI6
BioGRIDDUSP12
STRING (EMBL)DUSP12
ZODIACDUSP12
Ontologies - Pathways
QuickGOQ9UNI6
Ontology : AmiGOprotein tyrosine phosphatase activity  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  cellular protein modification process  protein dephosphorylation  protein tyrosine/serine/threonine phosphatase activity  zinc ion binding  dephosphorylation  phosphatase activity  kinase binding  positive regulation of glucokinase activity  peptidyl-tyrosine dephosphorylation  protein serine phosphatase activity  protein threonine phosphatase activity  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  cellular protein modification process  protein dephosphorylation  protein tyrosine/serine/threonine phosphatase activity  zinc ion binding  dephosphorylation  phosphatase activity  kinase binding  positive regulation of glucokinase activity  peptidyl-tyrosine dephosphorylation  protein serine phosphatase activity  protein threonine phosphatase activity  
NDEx NetworkDUSP12
Atlas of Cancer Signalling NetworkDUSP12
Wikipedia pathwaysDUSP12
Orthology - Evolution
OrthoDB11266
GeneTree (enSembl)ENSG00000081721
Phylogenetic Trees/Animal Genes : TreeFamDUSP12
Homologs : HomoloGeneDUSP12
Homology/Alignments : Family Browser (UCSC)DUSP12
Gene fusions - Rearrangements
Fusion : QuiverDUSP12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDUSP12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DUSP12
dbVarDUSP12
ClinVarDUSP12
MonarchDUSP12
1000_GenomesDUSP12 
Exome Variant ServerDUSP12
GNOMAD BrowserENSG00000081721
Varsome BrowserDUSP12
ACMGDUSP12 variants
VarityQ9UNI6
Genomic Variants (DGV)DUSP12 [DGVbeta]
DECIPHERDUSP12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDUSP12 
Mutations
ICGC Data PortalDUSP12 
TCGA Data PortalDUSP12 
Broad Tumor PortalDUSP12
OASIS PortalDUSP12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDUSP12  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDUSP12
Mutations and Diseases : HGMDDUSP12
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDUSP12
DgiDB (Drug Gene Interaction Database)DUSP12
DoCM (Curated mutations)DUSP12
CIViC (Clinical Interpretations of Variants in Cancer)DUSP12
Cancer3DDUSP12
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604835   
Orphanet
DisGeNETDUSP12
MedgenDUSP12
Genetic Testing Registry DUSP12
NextProtQ9UNI6 [Medical]
GENETestsDUSP12
Target ValidationDUSP12
Huge Navigator DUSP12 [HugePedia]
ClinGenDUSP12
Clinical trials, drugs, therapy
MyCancerGenomeDUSP12
Protein Interactions : CTDDUSP12
Pharm GKB GenePA27522
PharosQ9UNI6
Clinical trialDUSP12
Miscellaneous
canSAR (ICR)DUSP12
HarmonizomeDUSP12
DataMed IndexDUSP12
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDUSP12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:48:30 CEST 2021
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