Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DUSP15 (dual specificity phosphatase 15)

Identity

Alias_namesC20orf57
dual specificity phosphatase-like 15
chromosome 20 open reading frame 57
Alias_symbol (synonym)bA243J16.6
VHY
FLJ20645
bA243J16.5
Other alias
HGNC (Hugo) DUSP15
LocusID (NCBI) 128853
Atlas_Id 53941
Location 20q11.21  [Link to chromosome band 20q11]
Location_base_pair Starts at 31861067 and ends at 31870241 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNMT3B (20q11.21) / DUSP15 (20q11.21)NCOA3 (20q13.12) / DUSP15 (20q11.21)TPX2 (20q11.21) / DUSP15 (20q11.21)
DNMT3B 20q11.21 / DUSP15 20q11.21NCOA3 20q13.12 / DUSP15 20q11.21TPX2 20q11.21 / DUSP15 20q11.21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  DNMT3B/DUSP15 (20q11)
TPX2/DUSP15 (20q11)
t(20;20)(q11;q13) NCOA3/DUSP15


External links

Nomenclature
HGNC (Hugo)DUSP15   16236
Cards
Entrez_Gene (NCBI)DUSP15  128853  dual specificity phosphatase 15
AliasesC20orf57; VHY
GeneCards (Weizmann)DUSP15
Ensembl hg19 (Hinxton)ENSG00000149599 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149599 [Gene_View]  ENSG00000149599 [Sequence]  chr20:31861067-31870241 [Contig_View]  DUSP15 [Vega]
ICGC DataPortalENSG00000149599
TCGA cBioPortalDUSP15
AceView (NCBI)DUSP15
Genatlas (Paris)DUSP15
WikiGenes128853
SOURCE (Princeton)DUSP15
Genetics Home Reference (NIH)DUSP15
Genomic and cartography
GoldenPath hg38 (UCSC)DUSP15  -     chr20:31861067-31870241 -  20q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DUSP15  -     20q11.21   [Description]    (hg19-Feb_2009)
EnsemblDUSP15 - 20q11.21 [CytoView hg19]  DUSP15 - 20q11.21 [CytoView hg38]
Mapping of homologs : NCBIDUSP15 [Mapview hg19]  DUSP15 [Mapview hg38]
OMIM616776   
Gene and transcription
Genbank (Entrez)AI051640 AK000652 AK091960 AK097430 AL732169
RefSeq transcript (Entrez)NM_001012644 NM_001320478 NM_001320479 NM_080611 NM_177991
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DUSP15
Cluster EST : UnigeneHs.585017 [ NCBI ]
CGAP (NCI)Hs.585017
Alternative Splicing GalleryENSG00000149599
Gene ExpressionDUSP15 [ NCBI-GEO ]   DUSP15 [ EBI - ARRAY_EXPRESS ]   DUSP15 [ SEEK ]   DUSP15 [ MEM ]
Gene Expression Viewer (FireBrowse)DUSP15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)128853
GTEX Portal (Tissue expression)DUSP15
Human Protein AtlasENSG00000149599-DUSP15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H1R2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H1R2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H1R2
Splice isoforms : SwissVarQ9H1R2
PhosPhoSitePlusQ9H1R2
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)Atypical_DUSP    Dual-sp_phosphatase_cat-dom    DUSP    Prot-tyrosine_phosphatase-like    SMAD_FHA_dom_sf    Tyr_Pase_AS    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DSPc (PF00782)   
Domain families : Pfam (NCBI)pfam00782   
Domain families : Smart (EMBL)DSPc (SM00195)  
Conserved Domain (NCBI)DUSP15
DMDM Disease mutations128853
Blocks (Seattle)DUSP15
PDB (SRS)1YZ4   
PDB (PDBSum)1YZ4   
PDB (IMB)1YZ4   
PDB (RSDB)1YZ4   
Structural Biology KnowledgeBase1YZ4   
SCOP (Structural Classification of Proteins)1YZ4   
CATH (Classification of proteins structures)1YZ4   
SuperfamilyQ9H1R2
Human Protein Atlas [tissue]ENSG00000149599-DUSP15 [tissue]
Peptide AtlasQ9H1R2
HPRD13252
IPIIPI00171178   IPI00414846   IPI00419331   IPI00643635   IPI00640039   IPI00873368   
Protein Interaction databases
DIP (DOE-UCLA)Q9H1R2
IntAct (EBI)Q9H1R2
FunCoupENSG00000149599
BioGRIDDUSP15
STRING (EMBL)DUSP15
ZODIACDUSP15
Ontologies - Pathways
QuickGOQ9H1R2
Ontology : AmiGOprotein tyrosine phosphatase activity  protein binding  cytosol  cytosol  plasma membrane  transforming growth factor beta receptor signaling pathway  protein tyrosine/serine/threonine phosphatase activity  dephosphorylation  phosphatase activity  peptidyl-tyrosine dephosphorylation  regulation of cell proliferation  positive regulation of JNK cascade  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  protein binding  cytosol  cytosol  plasma membrane  transforming growth factor beta receptor signaling pathway  protein tyrosine/serine/threonine phosphatase activity  dephosphorylation  phosphatase activity  peptidyl-tyrosine dephosphorylation  regulation of cell proliferation  positive regulation of JNK cascade  
NDEx NetworkDUSP15
Atlas of Cancer Signalling NetworkDUSP15
Wikipedia pathwaysDUSP15
Orthology - Evolution
OrthoDB128853
GeneTree (enSembl)ENSG00000149599
Phylogenetic Trees/Animal Genes : TreeFamDUSP15
HOVERGENQ9H1R2
HOGENOMQ9H1R2
Homologs : HomoloGeneDUSP15
Homology/Alignments : Family Browser (UCSC)DUSP15
Gene fusions - Rearrangements
Fusion : MitelmanDNMT3B/DUSP15 [20q11.21/20q11.21]  [t(20;20)(q11;q11)]  
Fusion : MitelmanNCOA3/DUSP15 [20q13.12/20q11.21]  [t(20;20)(q11;q13)]  
Fusion : MitelmanTPX2/DUSP15 [20q11.21/20q11.21]  [t(20;20)(q11;q11)]  
Fusion PortalDNMT3B 20q11.21 DUSP15 20q11.21 BLCA
Fusion PortalNCOA3 20q13.12 DUSP15 20q11.21 BLCA
Fusion PortalTPX2 20q11.21 DUSP15 20q11.21 HNSC
Fusion : QuiverDUSP15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDUSP15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DUSP15
dbVarDUSP15
ClinVarDUSP15
1000_GenomesDUSP15 
Exome Variant ServerDUSP15
ExAC (Exome Aggregation Consortium)ENSG00000149599
GNOMAD BrowserENSG00000149599
Varsome BrowserDUSP15
Genetic variants : HAPMAP128853
Genomic Variants (DGV)DUSP15 [DGVbeta]
DECIPHERDUSP15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDUSP15 
Mutations
ICGC Data PortalDUSP15 
TCGA Data PortalDUSP15 
Broad Tumor PortalDUSP15
OASIS PortalDUSP15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDUSP15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDUSP15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DUSP15
DgiDB (Drug Gene Interaction Database)DUSP15
DoCM (Curated mutations)DUSP15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DUSP15 (select a term)
intoGenDUSP15
Cancer3DDUSP15(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616776   
Orphanet
DisGeNETDUSP15
MedgenDUSP15
Genetic Testing Registry DUSP15
NextProtQ9H1R2 [Medical]
TSGene128853
GENETestsDUSP15
Target ValidationDUSP15
Huge Navigator DUSP15 [HugePedia]
snp3D : Map Gene to Disease128853
BioCentury BCIQDUSP15
ClinGenDUSP15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD128853
Chemical/Pharm GKB GenePA27524
Clinical trialDUSP15
Miscellaneous
canSAR (ICR)DUSP15 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDUSP15
EVEXDUSP15
GoPubMedDUSP15
iHOPDUSP15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 27 11:20:13 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.