Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DUSP16 (dual specificity phosphatase 16)

Identity

Alias_symbol (synonym)MKP-7
KIAA1700
MKP7
Other alias
HGNC (Hugo) DUSP16
LocusID (NCBI) 80824
Atlas_Id 53365
Location 12p13.2  [Link to chromosome band 12p13]
Location_base_pair Starts at 12473282 and ends at 12562514 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DUSP16 (12p13.2) / BORCS5 (12p13.2)DUSP16 (12p13.2) / DUSP16 (12p13.2)DUSP16 (12p13.2) / ELF1 (13q14.11)
GDAP2 (1p12) / DUSP16 (12p13.2)DUSP16 12p13.2 LOH12CR1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DUSP16   17909
Cards
Entrez_Gene (NCBI)DUSP16  80824  dual specificity phosphatase 16
AliasesMKP-7; MKP7
GeneCards (Weizmann)DUSP16
Ensembl hg19 (Hinxton)ENSG00000111266 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111266 [Gene_View]  chr12:12473282-12562514 [Contig_View]  DUSP16 [Vega]
ICGC DataPortalENSG00000111266
TCGA cBioPortalDUSP16
AceView (NCBI)DUSP16
Genatlas (Paris)DUSP16
WikiGenes80824
SOURCE (Princeton)DUSP16
Genetics Home Reference (NIH)DUSP16
Genomic and cartography
GoldenPath hg38 (UCSC)DUSP16  -     chr12:12473282-12562514 -  12p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DUSP16  -     12p13.2   [Description]    (hg19-Feb_2009)
EnsemblDUSP16 - 12p13.2 [CytoView hg19]  DUSP16 - 12p13.2 [CytoView hg38]
Mapping of homologs : NCBIDUSP16 [Mapview hg19]  DUSP16 [Mapview hg38]
OMIM607175   
Gene and transcription
Genbank (Entrez)AB051487 AB052156 AF506796 AK022103 AK055973
RefSeq transcript (Entrez)NM_030640
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DUSP16
Cluster EST : UnigeneHs.536535 [ NCBI ]
CGAP (NCI)Hs.536535
Alternative Splicing GalleryENSG00000111266
Gene ExpressionDUSP16 [ NCBI-GEO ]   DUSP16 [ EBI - ARRAY_EXPRESS ]   DUSP16 [ SEEK ]   DUSP16 [ MEM ]
Gene Expression Viewer (FireBrowse)DUSP16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80824
GTEX Portal (Tissue expression)DUSP16
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BY84   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BY84  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BY84
Splice isoforms : SwissVarQ9BY84
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
PhosPhoSitePlusQ9BY84
Domaine pattern : Prosite (Expaxy)RHODANESE_3 (PS50206)    TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)Dual-sp_phosphatase_cat-dom    DUSP    MKP    Prot-tyrosine_phosphatase-like    Rhodanese-like_dom    Tyr_Pase_AS    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DSPc (PF00782)    Rhodanese (PF00581)   
Domain families : Pfam (NCBI)pfam00782    pfam00581   
Domain families : Smart (EMBL)DSPc (SM00195)  RHOD (SM00450)  
Conserved Domain (NCBI)DUSP16
DMDM Disease mutations80824
Blocks (Seattle)DUSP16
PDB (SRS)2VSW    3TG3    4YR8   
PDB (PDBSum)2VSW    3TG3    4YR8   
PDB (IMB)2VSW    3TG3    4YR8   
PDB (RSDB)2VSW    3TG3    4YR8   
Structural Biology KnowledgeBase2VSW    3TG3    4YR8   
SCOP (Structural Classification of Proteins)2VSW    3TG3    4YR8   
CATH (Classification of proteins structures)2VSW    3TG3    4YR8   
SuperfamilyQ9BY84
Human Protein AtlasENSG00000111266
Peptide AtlasQ9BY84
HPRD09525
IPIIPI00028428   IPI00045065   IPI01013138   
Protein Interaction databases
DIP (DOE-UCLA)Q9BY84
IntAct (EBI)Q9BY84
FunCoupENSG00000111266
BioGRIDDUSP16
STRING (EMBL)DUSP16
ZODIACDUSP16
Ontologies - Pathways
QuickGOQ9BY84
Ontology : AmiGOinactivation of MAPK activity  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  nucleus  nucleoplasm  cytoplasm  cytosol  dephosphorylation  dephosphorylation  phosphatase activity  MAP kinase tyrosine/serine/threonine phosphatase activity  cytoplasmic vesicle  peptidyl-tyrosine dephosphorylation  MAPK export from nucleus  MAPK phosphatase export from nucleus, leptomycin B sensitive  
Ontology : EGO-EBIinactivation of MAPK activity  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  nucleus  nucleoplasm  cytoplasm  cytosol  dephosphorylation  dephosphorylation  phosphatase activity  MAP kinase tyrosine/serine/threonine phosphatase activity  cytoplasmic vesicle  peptidyl-tyrosine dephosphorylation  MAPK export from nucleus  MAPK phosphatase export from nucleus, leptomycin B sensitive  
Pathways : KEGGMAPK signaling pathway   
NDEx NetworkDUSP16
Atlas of Cancer Signalling NetworkDUSP16
Wikipedia pathwaysDUSP16
Orthology - Evolution
OrthoDB80824
GeneTree (enSembl)ENSG00000111266
Phylogenetic Trees/Animal Genes : TreeFamDUSP16
HOVERGENQ9BY84
HOGENOMQ9BY84
Homologs : HomoloGeneDUSP16
Homology/Alignments : Family Browser (UCSC)DUSP16
Gene fusions - Rearrangements
Fusion : MitelmanDUSP16/LOH12CR1 [12p13.2/]  
Fusion: TCGADUSP16 12p13.2 LOH12CR1 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDUSP16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DUSP16
dbVarDUSP16
ClinVarDUSP16
1000_GenomesDUSP16 
Exome Variant ServerDUSP16
ExAC (Exome Aggregation Consortium)DUSP16 (select the gene name)
Genetic variants : HAPMAP80824
Genomic Variants (DGV)DUSP16 [DGVbeta]
DECIPHERDUSP16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDUSP16 
Mutations
ICGC Data PortalDUSP16 
TCGA Data PortalDUSP16 
Broad Tumor PortalDUSP16
OASIS PortalDUSP16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDUSP16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDUSP16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DUSP16
DgiDB (Drug Gene Interaction Database)DUSP16
DoCM (Curated mutations)DUSP16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DUSP16 (select a term)
intoGenDUSP16
Cancer3DDUSP16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607175   
Orphanet
MedgenDUSP16
Genetic Testing Registry DUSP16
NextProtQ9BY84 [Medical]
TSGene80824
GENETestsDUSP16
Target ValidationDUSP16
Huge Navigator DUSP16 [HugePedia]
snp3D : Map Gene to Disease80824
BioCentury BCIQDUSP16
ClinGenDUSP16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80824
Chemical/Pharm GKB GenePA38475
Clinical trialDUSP16
Miscellaneous
canSAR (ICR)DUSP16 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDUSP16
EVEXDUSP16
GoPubMedDUSP16
iHOPDUSP16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:31:53 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.