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DUSP19 (dual specificity phosphatase 19)

Identity

Alias_symbol (synonym)SKRP1
DUSP17
Other aliasLMWDSP3
TS-DSP1
HGNC (Hugo) DUSP19
LocusID (NCBI) 142679
Atlas_Id 52137
Location 2q32.1  [Link to chromosome band 2q32]
Location_base_pair Starts at 183943287 and ends at 183964722 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DUSP19   18894
Cards
Entrez_Gene (NCBI)DUSP19  142679  dual specificity phosphatase 19
AliasesDUSP17; LMWDSP3; SKRP1; TS-DSP1
GeneCards (Weizmann)DUSP19
Ensembl hg19 (Hinxton)ENSG00000162999 [Gene_View]  chr2:183943287-183964722 [Contig_View]  DUSP19 [Vega]
Ensembl hg38 (Hinxton)ENSG00000162999 [Gene_View]  chr2:183943287-183964722 [Contig_View]  DUSP19 [Vega]
ICGC DataPortalENSG00000162999
TCGA cBioPortalDUSP19
AceView (NCBI)DUSP19
Genatlas (Paris)DUSP19
WikiGenes142679
SOURCE (Princeton)DUSP19
Genetics Home Reference (NIH)DUSP19
Genomic and cartography
GoldenPath hg19 (UCSC)DUSP19  -     chr2:183943287-183964722 +  2q32.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DUSP19  -     2q32.1   [Description]    (hg38-Dec_2013)
EnsemblDUSP19 - 2q32.1 [CytoView hg19]  DUSP19 - 2q32.1 [CytoView hg38]
Mapping of homologs : NCBIDUSP19 [Mapview hg19]  DUSP19 [Mapview hg38]
OMIM611437   
Gene and transcription
Genbank (Entrez)AB038770 AB063186 AB063187 AF486808 AK094800
RefSeq transcript (Entrez)NM_001142314 NM_001321519 NM_080876
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)DUSP19
Cluster EST : UnigeneHs.132237 [ NCBI ]
CGAP (NCI)Hs.132237
Alternative Splicing GalleryENSG00000162999
Gene ExpressionDUSP19 [ NCBI-GEO ]   DUSP19 [ EBI - ARRAY_EXPRESS ]   DUSP19 [ SEEK ]   DUSP19 [ MEM ]
Gene Expression Viewer (FireBrowse)DUSP19 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)142679
GTEX Portal (Tissue expression)DUSP19
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WTR2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WTR2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WTR2
Splice isoforms : SwissVarQ8WTR2
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
PhosPhoSitePlusQ8WTR2
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)Atypical_DUSP    Dual-sp_phosphatase_cat-dom    DUSP    Prot-tyrosine_phosphatase-like    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DSPc (PF00782)   
Domain families : Pfam (NCBI)pfam00782   
Domain families : Smart (EMBL)DSPc (SM00195)  
Conserved Domain (NCBI)DUSP19
DMDM Disease mutations142679
Blocks (Seattle)DUSP19
PDB (SRS)3S4E    4D3P    4D3Q    4D3R   
PDB (PDBSum)3S4E    4D3P    4D3Q    4D3R   
PDB (IMB)3S4E    4D3P    4D3Q    4D3R   
PDB (RSDB)3S4E    4D3P    4D3Q    4D3R   
Structural Biology KnowledgeBase3S4E    4D3P    4D3Q    4D3R   
SCOP (Structural Classification of Proteins)3S4E    4D3P    4D3Q    4D3R   
CATH (Classification of proteins structures)3S4E    4D3P    4D3Q    4D3R   
SuperfamilyQ8WTR2
Human Protein AtlasENSG00000162999
Peptide AtlasQ8WTR2
HPRD13254
IPIIPI00102808   IPI00218179   
Protein Interaction databases
DIP (DOE-UCLA)Q8WTR2
IntAct (EBI)Q8WTR2
FunCoupENSG00000162999
BioGRIDDUSP19
STRING (EMBL)DUSP19
ZODIACDUSP19
Ontologies - Pathways
QuickGOQ8WTR2
Ontology : AmiGOprotein tyrosine phosphatase activity  protein kinase inhibitor activity  MAP-kinase scaffold activity  protein binding  negative regulation of protein kinase activity  JUN kinase phosphatase activity  protein kinase activator activity  mitogen-activated protein kinase kinase kinase binding  activation of protein kinase activity  peptidyl-tyrosine dephosphorylation  positive regulation of MAPK cascade  positive regulation of JUN kinase activity  negative regulation of JUN kinase activity  positive regulation of protein kinase activity  negative regulation of JNK cascade  positive regulation of JNK cascade  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  protein kinase inhibitor activity  MAP-kinase scaffold activity  protein binding  negative regulation of protein kinase activity  JUN kinase phosphatase activity  protein kinase activator activity  mitogen-activated protein kinase kinase kinase binding  activation of protein kinase activity  peptidyl-tyrosine dephosphorylation  positive regulation of MAPK cascade  positive regulation of JUN kinase activity  negative regulation of JUN kinase activity  positive regulation of protein kinase activity  negative regulation of JNK cascade  positive regulation of JNK cascade  
NDEx NetworkDUSP19
Atlas of Cancer Signalling NetworkDUSP19
Wikipedia pathwaysDUSP19
Orthology - Evolution
OrthoDB142679
GeneTree (enSembl)ENSG00000162999
Phylogenetic Trees/Animal Genes : TreeFamDUSP19
HOVERGENQ8WTR2
HOGENOMQ8WTR2
Homologs : HomoloGeneDUSP19
Homology/Alignments : Family Browser (UCSC)DUSP19
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDUSP19 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DUSP19
dbVarDUSP19
ClinVarDUSP19
1000_GenomesDUSP19 
Exome Variant ServerDUSP19
ExAC (Exome Aggregation Consortium)DUSP19 (select the gene name)
Genetic variants : HAPMAP142679
Genomic Variants (DGV)DUSP19 [DGVbeta]
DECIPHER (Syndromes)2:183943287-183964722  ENSG00000162999
CONAN: Copy Number AnalysisDUSP19 
Mutations
ICGC Data PortalDUSP19 
TCGA Data PortalDUSP19 
Broad Tumor PortalDUSP19
OASIS PortalDUSP19 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDUSP19  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDUSP19
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DUSP19
DgiDB (Drug Gene Interaction Database)DUSP19
DoCM (Curated mutations)DUSP19 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DUSP19 (select a term)
intoGenDUSP19
Cancer3DDUSP19(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611437   
Orphanet
MedgenDUSP19
Genetic Testing Registry DUSP19
NextProtQ8WTR2 [Medical]
TSGene142679
GENETestsDUSP19
Huge Navigator DUSP19 [HugePedia]
snp3D : Map Gene to Disease142679
BioCentury BCIQDUSP19
ClinGenDUSP19
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD142679
Chemical/Pharm GKB GenePA134895660
Clinical trialDUSP19
Miscellaneous
canSAR (ICR)DUSP19 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDUSP19
EVEXDUSP19
GoPubMedDUSP19
iHOPDUSP19
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:04:00 CET 2017

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