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DUSP21 (dual specificity phosphatase 21)

Identity

Other aliasLMWDSP21
HGNC (Hugo) DUSP21
LocusID (NCBI) 63904
Atlas_Id 53928
Location Xp11.3  [Link to chromosome band Xp11]
Location_base_pair Starts at 44844003 and ends at 44844888 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DUSP21   20476
Cards
Entrez_Gene (NCBI)DUSP21  63904  dual specificity phosphatase 21
AliasesLMWDSP21
GeneCards (Weizmann)DUSP21
Ensembl hg19 (Hinxton)ENSG00000189037 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000189037 [Gene_View]  ENSG00000189037 [Sequence]  chrX:44844003-44844888 [Contig_View]  DUSP21 [Vega]
ICGC DataPortalENSG00000189037
TCGA cBioPortalDUSP21
AceView (NCBI)DUSP21
Genatlas (Paris)DUSP21
WikiGenes63904
SOURCE (Princeton)DUSP21
Genetics Home Reference (NIH)DUSP21
Genomic and cartography
GoldenPath hg38 (UCSC)DUSP21  -     chrX:44844003-44844888 +  Xp11.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DUSP21  -     Xp11.3   [Description]    (hg19-Feb_2009)
EnsemblDUSP21 - Xp11.3 [CytoView hg19]  DUSP21 - Xp11.3 [CytoView hg38]
Mapping of homologs : NCBIDUSP21 [Mapview hg19]  DUSP21 [Mapview hg38]
OMIM300678   
Gene and transcription
Genbank (Entrez)AA813372 AF143321 AF533018 AY121807 AY156515
RefSeq transcript (Entrez)NM_022076
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DUSP21
Cluster EST : UnigeneHs.534478 [ NCBI ]
CGAP (NCI)Hs.534478
Alternative Splicing GalleryENSG00000189037
Gene ExpressionDUSP21 [ NCBI-GEO ]   DUSP21 [ EBI - ARRAY_EXPRESS ]   DUSP21 [ SEEK ]   DUSP21 [ MEM ]
Gene Expression Viewer (FireBrowse)DUSP21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63904
GTEX Portal (Tissue expression)DUSP21
Human Protein AtlasENSG00000189037-DUSP21 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H596   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H596  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H596
Splice isoforms : SwissVarQ9H596
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
PhosPhoSitePlusQ9H596
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)Atypical_DUSP    Atypical_DUSP_famB    Dual-sp_phosphatase_cat-dom    DUSP    Prot-tyrosine_phosphatase-like    Tyr_Pase_AS    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DSPc (PF00782)   
Domain families : Pfam (NCBI)pfam00782   
Domain families : Smart (EMBL)DSPc (SM00195)  
Conserved Domain (NCBI)DUSP21
DMDM Disease mutations63904
Blocks (Seattle)DUSP21
SuperfamilyQ9H596
Human Protein Atlas [tissue]ENSG00000189037-DUSP21 [tissue]
Peptide AtlasQ9H596
HPRD06494
IPIIPI00419454   IPI01012648   
Protein Interaction databases
DIP (DOE-UCLA)Q9H596
IntAct (EBI)Q9H596
FunCoupENSG00000189037
BioGRIDDUSP21
STRING (EMBL)DUSP21
ZODIACDUSP21
Ontologies - Pathways
QuickGOQ9H596
Ontology : AmiGOinactivation of MAPK activity  protein tyrosine phosphatase activity  protein binding  nucleus  cytoplasm  mitochondrial matrix  MAP kinase tyrosine/serine/threonine phosphatase activity  extrinsic component of mitochondrial inner membrane  peptidyl-tyrosine dephosphorylation  
Ontology : EGO-EBIinactivation of MAPK activity  protein tyrosine phosphatase activity  protein binding  nucleus  cytoplasm  mitochondrial matrix  MAP kinase tyrosine/serine/threonine phosphatase activity  extrinsic component of mitochondrial inner membrane  peptidyl-tyrosine dephosphorylation  
NDEx NetworkDUSP21
Atlas of Cancer Signalling NetworkDUSP21
Wikipedia pathwaysDUSP21
Orthology - Evolution
OrthoDB63904
GeneTree (enSembl)ENSG00000189037
Phylogenetic Trees/Animal Genes : TreeFamDUSP21
HOVERGENQ9H596
HOGENOMQ9H596
Homologs : HomoloGeneDUSP21
Homology/Alignments : Family Browser (UCSC)DUSP21
Gene fusions - Rearrangements
Fusion : QuiverDUSP21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDUSP21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DUSP21
dbVarDUSP21
ClinVarDUSP21
1000_GenomesDUSP21 
Exome Variant ServerDUSP21
ExAC (Exome Aggregation Consortium)ENSG00000189037
GNOMAD BrowserENSG00000189037
Genetic variants : HAPMAP63904
Genomic Variants (DGV)DUSP21 [DGVbeta]
DECIPHERDUSP21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDUSP21 
Mutations
ICGC Data PortalDUSP21 
TCGA Data PortalDUSP21 
Broad Tumor PortalDUSP21
OASIS PortalDUSP21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDUSP21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDUSP21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch DUSP21
DgiDB (Drug Gene Interaction Database)DUSP21
DoCM (Curated mutations)DUSP21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DUSP21 (select a term)
intoGenDUSP21
Cancer3DDUSP21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300678   
Orphanet
DisGeNETDUSP21
MedgenDUSP21
Genetic Testing Registry DUSP21
NextProtQ9H596 [Medical]
TSGene63904
GENETestsDUSP21
Target ValidationDUSP21
Huge Navigator DUSP21 [HugePedia]
snp3D : Map Gene to Disease63904
BioCentury BCIQDUSP21
ClinGenDUSP21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63904
Chemical/Pharm GKB GenePA134967875
Clinical trialDUSP21
Miscellaneous
canSAR (ICR)DUSP21 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDUSP21
EVEXDUSP21
GoPubMedDUSP21
iHOPDUSP21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:23:27 CEST 2018

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