Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DUSP7 (dual specificity phosphatase 7)

Identity

Other namesMKPX
PYST2
HGNC (Hugo) DUSP7
LocusID (NCBI) 1849
Location 3p21.2
Location_base_pair Starts at 52082937 and ends at 52090461 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DUSP7   3073
Entrez_Gene (NCBI)DUSP7  1849  dual specificity phosphatase 7
Cards
GeneCards (Weizmann)DUSP7
Ensembl (Hinxton)ENSG00000164086 [Gene_View]  chr3:52082937-52090461 [Contig_View]  DUSP7 [Vega]
AceView (NCBI)DUSP7
Genatlas (Paris)DUSP7
SOURCE (Stanford)NM_001947
Genomic and cartography
GoldenPath (UCSC)DUSP7  -  3p21.2   chr3:52082937-52090461 -  3p21.2   [Description]    (hg19-Feb_2009)
EnsemblDUSP7 - 3p21.2 [CytoView]
Mapping of homologs : NCBIDUSP7 [Mapview]
OMIM602749   
Gene and transcription
Genbank (Entrez)AF508727 AF508728 AL110157 BC019107 BC104880
RefSeq transcript (SRS)NM_001947
RefSeq transcript (Entrez)NM_001947
RefSeq genomic (SRS)AC_000135 NC_000003 NC_018914 NT_022517 NW_001838877 NW_004078011
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NT_022517 NW_001838877 NW_004078011
Consensus coding sequences : CCDS (NCBI)DUSP7
Cluster EST : UnigeneHs.591664 [ SRS ] Hs.591664 [ NCBI ]
CGAP (NCI)Hs.591664
Alternative Splicing : Fast-db (Paris)GSHG0021755
Alternative Splicing GalleryENSG00000164086
Gene ExpressionDUSP7 [ NCBI-GEO ]   DUSP7 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16829 (SRS) Q16829 (Uniprot)
NextProtQ16829
With graphics : InterProQ16829
Splice isoforms : SwissVarQ16829(Swissvar)
Domaine pattern : Prosite (SRS)RHODANESE_3 (PS50206)    TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domaine pattern : Prosite (Expaxy)RHODANESE_3 (PS50206)    TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (SRS)Dual-sp_phosphatase_cat-dom    Dual-sp_phosphatase_subgr_cat    DUSP    MKP    Rhodanese-like_dom    Tyr/Dual-specificity_Pase   
Domains : Interpro (EBI)Dual-sp_phosphatase_cat-dom    Dual-sp_phosphatase_subgr_cat    DUSP    MKP    Rhodanese-like_dom    Tyr/Dual-specificity_Pase   
Related proteins : CluSTrQ16829
Domain families : Pfam (SRS)DSPc (PF00782)    Rhodanese (PF00581)   
Domain families : Pfam (Sanger)DSPc (PF00782)    Rhodanese (PF00581)   
Domain families : Pfam (NCBI)pfam00782    pfam00581   
Domain families : Smart (EMBL)DSPc (SM00195)  RHOD (SM00450)  
DMDM1849
Blocks (Seattle)Q16829
Human Protein AtlasENSG00000164086
HPRD04125
IPIIPI00394738   IPI00944963   IPI00945121   
Protein Interaction databases
DIP (DOE-UCLA)Q16829
IntAct (EBI)Q16829
FunCoupENSG00000164086
REACTOMEDUSP7
Protein Interaction Database1849
BioGRIDDUSP7
InParanoidQ16829
Interologous Interaction database Q16829
IntegromeDBDUSP7
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)DUSP7
SNP (GeneSNP Utah)DUSP7
SNP : HGBaseDUSP7
Genetic variants : HAPMAPDUSP7
Somatic Mutations in Cancer : COSMICDUSP7 
CONAN: Copy Number AnalysisDUSP7 
Mutations and Diseases : HGMDDUSP7
OMIM602749   
GENETests602749   
Disease Genetic AssociationDUSP7
Huge Navigator DUSP7 [HugePedia]  DUSP7 [HugeCancerGEM]
Genomic VariantsDUSP7  DUSP7 [DGVbeta]
snp3D : Map Gene to Disease1849
General knowledge
Homologs : HomoloGeneDUSP7
Homology/Alignments : Family Browser (UCSC)DUSP7
Phylogenetic Trees/Animal Genes : TreeFamDUSP7
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.16 [ Enzyme-SRS ]   3.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
Chemical/Protein Interactions : CTD1849
Chemical/Pharm GKB GenePA27530
Clinical trialDUSP7
Cancer Resource (Charite)ENSG00000164086
Ontology : AmiGOinactivation of MAPK activity  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  protein tyrosine phosphatase activity  protein binding  nucleoplasm  cytosol  Toll signaling pathway  MAP kinase tyrosine/serine/threonine phosphatase activity  toll-like receptor 1 signaling pathway  toll-like receptor 2 signaling pathway  toll-like receptor 3 signaling pathway  toll-like receptor 4 signaling pathway  peptidyl-tyrosine dephosphorylation  TRIF-dependent toll-like receptor signaling pathway  negative regulation of MAP kinase activity  innate immune response  nerve growth factor receptor signaling pathway  stress-activated MAPK cascade  
Ontology : EGO-EBIinactivation of MAPK activity  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  protein tyrosine phosphatase activity  protein binding  nucleoplasm  cytosol  Toll signaling pathway  MAP kinase tyrosine/serine/threonine phosphatase activity  toll-like receptor 1 signaling pathway  toll-like receptor 2 signaling pathway  toll-like receptor 3 signaling pathway  toll-like receptor 4 signaling pathway  peptidyl-tyrosine dephosphorylation  TRIF-dependent toll-like receptor signaling pathway  negative regulation of MAP kinase activity  innate immune response  nerve growth factor receptor signaling pathway  stress-activated MAPK cascade  
Pathways : KEGGMAPK signaling pathway
Other databases
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
PubGeneDUSP7
iHOPDUSP7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:26:21 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.