DUSP8 (dual specificity phosphatase 8)

Identity

Other names	C11orf81
	FLJ42476
	FLJ42958
	HB5
	HVH-5
	HVH8
HGNC	DUSP8
Location	11p15.5
Location_base_pair	Starts at 1531857 and ends at 1549726 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DUSP8   3074
Entrez_Gene	DUSP8  1850  dual specificity phosphatase 8
	Cards
GeneCards	DUSP8
Ensembl	DUSP8 [Search_View]   ENSG00000184545 [Gene_View]
Genatlas	DUSP8
GeneLynx	DUSP8
eGenome	DUSP8
euGene	1850
	Genomic and cartography
GoldenPath	DUSP8  -  11p15.5   chr11:1531857-1549726 -  11p15.5   [Description]    (hg18-March_2006)
Ensembl	DUSP8 - 11p15.5 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DUSP8
	Gene and transcription
Genbank	AK124467 [ ENTREZ ]
Genbank	AK124948 [ ENTREZ ]
Genbank	BC038231 [ ENTREZ ]
Genbank	BC045110 [ ENTREZ ]
Genbank	BU740880 [ ENTREZ ]
RefSeq	NM_004420 [ SRS ]    NM_004420 [ ENTREZ ]
RefSeq	AC_000054 [ SRS ]    AC_000054 [ ENTREZ ]
RefSeq	AC_000143 [ SRS ]    AC_000143 [ ENTREZ ]
RefSeq	NC_000011 [ SRS ]    NC_000011 [ ENTREZ ]
RefSeq	NT_009237 [ SRS ]    NT_009237 [ ENTREZ ]
RefSeq	NW_001838017 [ SRS ]    NW_001838017 [ ENTREZ ]
RefSeq	NW_924962 [ SRS ]    NW_924962 [ ENTREZ ]
AceView	DUSP8 AceView - NCBI
Unigene	Hs.41688 [ SRS ]    Hs.41688 [ NCBI ]     HS41688 [ spliceNest ]
Fast-db	676 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q13202 [ SRS]    Q13202 [ EXPASY ]     Q13202 [ INTERPRO ]     Q13202 [ UNIPROT ]
Prosite	PS50206 RHODANESE_3 [ SRS ]    PS50206 RHODANESE_3 [ Expasy ]
Prosite	PS00383 TYR_PHOSPHATASE_1 [ SRS ]    PS00383 TYR_PHOSPHATASE_1 [ Expasy ]
Prosite	PS50056 TYR_PHOSPHATASE_2 [ SRS ]    PS50056 TYR_PHOSPHATASE_2 [ Expasy ]
Prosite	PS50054 TYR_PHOSPHATASE_DUAL [ SRS ]    PS50054 TYR_PHOSPHATASE_DUAL [ Expasy ]
Interpro	IPR008343 MAPK_phosph [ SRS ]    IPR008343 MAPK_phosph [ EBI ]
Interpro	IPR001763 Rhodanese-like [ SRS ]    IPR001763 Rhodanese-like [ EBI ]
Interpro	IPR000387 Tyr_Pase [ SRS ]    IPR000387 Tyr_Pase [ EBI ]
Interpro	IPR016130 Tyr_Pase_AS [ SRS ]    IPR016130 Tyr_Pase_AS [ EBI ]
Interpro	IPR000340 Tyr_Pase_dual_specific [ SRS ]    IPR000340 Tyr_Pase_dual_specific [ EBI ]
CluSTr	Q13202
Pfam	PF00782 DSPc [ SRS ]    PF00782 DSPc [ Sanger ]    pfam00782 [ NCBI-CDD ]
Smart	SM00195 DSPc [EMBL]
Smart	SM00450 RHOD [EMBL]
Blocks	Q13202
HPRD	03617
	Protein Interaction databases
DIP	Q13202
IntAct	Q13202
	Polymorphism : SNP, mutations, diseases
OMIM	602038    [ map ]
GENECLINICS	602038
SNP	DUSP8 [dbSNP-NCBI]
SNP	NM_004420 [SNP-NCI]
SNP	DUSP8 [GeneSNPs - Utah]  DUSP8] [HGBASE - SRS]
HAPMAP	DUSP8 [HAPMAP]
COSMIC	DUSP8 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	DUSP8
	General knowledge
Family Browser	DUSP8 [UCSC Family Browser]
SOURCE	NM_004420
SMD	Hs.41688
SAGE	Hs.41688
Enzyme	3.1.3.48 [ Enzyme-Expasy ]   3.1.3.48 [ Enzyme-SRS ]   3.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]   3.1.3.48 [ WIT ]
GO	inactivation of MAPK activity [Amigo]  inactivation of MAPK activity
GO	protein tyrosine phosphatase activity [Amigo]  protein tyrosine phosphatase activity
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	protein amino acid dephosphorylation [Amigo]  protein amino acid dephosphorylation
GO	hydrolase activity [Amigo]  hydrolase activity
GO	MAP kinase tyrosine/serine/threonine phosphatase activity [Amigo]  MAP kinase tyrosine/serine/threonine phosphatase activity
BIOCARTA	Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases    [Genes]
KEGG	MAPK signaling pathway
PubGene	DUSP8
TreeFam	DUSP8
CTD	1850 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DUSP8 Related clones (RZPD - Berlin)
	PubMed
PubMed	6 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:39:14 2008