Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DXO (decapping exoribonuclease)

Identity

Alias_namesDOM3Z
DOM-3 (C. elegans) homolog Z
dom-3 homolog Z (C. elegans)
Other aliasDOM3L
NG6
RAI1
HGNC (Hugo) DXO
LocusID (NCBI) 1797
Atlas_Id 62684
Location 6p21.33  [Link to chromosome band 6p21]
Location_base_pair Starts at 31969811 and ends at 31972255 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DXO (6p21.33) / CLK2 (1q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DXO   2992
Cards
Entrez_Gene (NCBI)DXO  1797  decapping exoribonuclease
AliasesDOM3L; DOM3Z; NG6; RAI1
GeneCards (Weizmann)DXO
Ensembl hg19 (Hinxton)ENSG00000204348 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204348 [Gene_View]  chr6:31969811-31972255 [Contig_View]  DXO [Vega]
ICGC DataPortalENSG00000204348
TCGA cBioPortalDXO
AceView (NCBI)DXO
Genatlas (Paris)DXO
WikiGenes1797
SOURCE (Princeton)DXO
Genetics Home Reference (NIH)DXO
Genomic and cartography
GoldenPath hg38 (UCSC)DXO  -     chr6:31969811-31972255 -  6p21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DXO  -     6p21.33   [Description]    (hg19-Feb_2009)
EnsemblDXO - 6p21.33 [CytoView hg19]  DXO - 6p21.33 [CytoView hg38]
Mapping of homologs : NCBIDXO [Mapview hg19]  DXO [Mapview hg38]
OMIM605996   
Gene and transcription
Genbank (Entrez)AF059252 AF059253 AF059254 AK310107 BC009344
RefSeq transcript (Entrez)NM_005510
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_113891 NT_167245 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)DXO
Cluster EST : UnigeneHs.153299 [ NCBI ]
CGAP (NCI)Hs.153299
Alternative Splicing GalleryENSG00000204348
Gene ExpressionDXO [ NCBI-GEO ]   DXO [ EBI - ARRAY_EXPRESS ]   DXO [ SEEK ]   DXO [ MEM ]
Gene Expression Viewer (FireBrowse)DXO [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1797
GTEX Portal (Tissue expression)DXO
Human Protein AtlasENSG00000204348-DXO [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO77932   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO77932  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO77932
Splice isoforms : SwissVarO77932
Catalytic activity : Enzyme3.1.13.- [ Enzyme-Expasy ]   3.1.13.-3.1.13.- [ IntEnz-EBI ]   3.1.13.- [ BRENDA ]   3.1.13.- [ KEGG ]   
PhosPhoSitePlusO77932
Domains : Interpro (EBI)RAI1   
Domain families : Pfam (Sanger)RAI1 (PF08652)   
Domain families : Pfam (NCBI)pfam08652   
Conserved Domain (NCBI)DXO
DMDM Disease mutations1797
Blocks (Seattle)DXO
SuperfamilyO77932
Human Protein Atlas [tissue]ENSG00000204348-DXO [tissue]
Peptide AtlasO77932
HPRD16186
IPIIPI00147644   IPI00946682   IPI00946930   
Protein Interaction databases
DIP (DOE-UCLA)O77932
IntAct (EBI)O77932
FunCoupENSG00000204348
BioGRIDDXO
STRING (EMBL)DXO
ZODIACDXO
Ontologies - Pathways
QuickGOO77932
Ontology : AmiGOnucleotide binding  magnesium ion binding  mRNA binding  nucleus  cytosol  plasma membrane  mRNA catabolic process  metabolic process  5'-3' exonuclease activity  RNA pyrophosphohydrolase activity  RNA destabilization  nuclear mRNA surveillance  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBInucleotide binding  magnesium ion binding  mRNA binding  nucleus  cytosol  plasma membrane  mRNA catabolic process  metabolic process  5'-3' exonuclease activity  RNA pyrophosphohydrolase activity  RNA destabilization  nuclear mRNA surveillance  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkDXO
Atlas of Cancer Signalling NetworkDXO
Wikipedia pathwaysDXO
Orthology - Evolution
OrthoDB1797
GeneTree (enSembl)ENSG00000204348
Phylogenetic Trees/Animal Genes : TreeFamDXO
HOVERGENO77932
HOGENOMO77932
Homologs : HomoloGeneDXO
Homology/Alignments : Family Browser (UCSC)DXO
Gene fusions - Rearrangements
Fusion: Tumor Portal DXO
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDXO [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DXO
dbVarDXO
ClinVarDXO
1000_GenomesDXO 
Exome Variant ServerDXO
ExAC (Exome Aggregation Consortium)ENSG00000204348
GNOMAD BrowserENSG00000204348
Genetic variants : HAPMAP1797
Genomic Variants (DGV)DXO [DGVbeta]
DECIPHERDXO [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDXO 
Mutations
ICGC Data PortalDXO 
TCGA Data PortalDXO 
Broad Tumor PortalDXO
OASIS PortalDXO [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDDXO
BioMutasearch DXO
DgiDB (Drug Gene Interaction Database)DXO
DoCM (Curated mutations)DXO (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DXO (select a term)
intoGenDXO
Cancer3DDXO(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605996   
Orphanet
MedgenDXO
Genetic Testing Registry DXO
NextProtO77932 [Medical]
TSGene1797
GENETestsDXO
Target ValidationDXO
Huge Navigator DXO [HugePedia]
snp3D : Map Gene to Disease1797
BioCentury BCIQDXO
ClinGenDXO
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1797
Chemical/Pharm GKB GenePA27458
Clinical trialDXO
Miscellaneous
canSAR (ICR)DXO (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDXO
EVEXDXO
GoPubMedDXO
iHOPDXO
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Nov 9 11:45:18 CET 2017

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