Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DYNC1LI1 (dynein cytoplasmic 1 light intermediate chain 1)

Identity

Alias_namesDNCLI1
dynein, cytoplasmic, light intermediate polypeptide 1
Other aliasDLC-A
LIC1
HGNC (Hugo) DYNC1LI1
LocusID (NCBI) 51143
Atlas_Id 62689
Location 3p22.3  [Link to chromosome band 3p22]
Location_base_pair Starts at 32525971 and ends at 32570924 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DYNC1LI1 (3p22.3) / DYNC1LI1 (3p22.3)DYNC1LI1 (3p22.3) / GADL1 (3p24.1)DYNC1LI1 (3p22.3) / PXK (3p14.3)
DYNC1LI1 (3p22.3) / ZRANB3 (2q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DYNC1LI1   18745
Cards
Entrez_Gene (NCBI)DYNC1LI1  51143  dynein cytoplasmic 1 light intermediate chain 1
AliasesDLC-A; DNCLI1; LIC1
GeneCards (Weizmann)DYNC1LI1
Ensembl hg19 (Hinxton)ENSG00000144635 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144635 [Gene_View]  chr3:32525971-32570924 [Contig_View]  DYNC1LI1 [Vega]
ICGC DataPortalENSG00000144635
TCGA cBioPortalDYNC1LI1
AceView (NCBI)DYNC1LI1
Genatlas (Paris)DYNC1LI1
WikiGenes51143
SOURCE (Princeton)DYNC1LI1
Genetics Home Reference (NIH)DYNC1LI1
Genomic and cartography
GoldenPath hg38 (UCSC)DYNC1LI1  -     chr3:32525971-32570924 -  3p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DYNC1LI1  -     3p22.3   [Description]    (hg19-Feb_2009)
EnsemblDYNC1LI1 - 3p22.3 [CytoView hg19]  DYNC1LI1 - 3p22.3 [CytoView hg38]
Mapping of homologs : NCBIDYNC1LI1 [Mapview hg19]  DYNC1LI1 [Mapview hg38]
OMIM615890   
Gene and transcription
Genbank (Entrez)AF078849 AK001081 AK074348 AK222573 AK222653
RefSeq transcript (Entrez)NM_001329135 NM_016141
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DYNC1LI1
Cluster EST : UnigeneHs.529495 [ NCBI ]
CGAP (NCI)Hs.529495
Alternative Splicing GalleryENSG00000144635
Gene ExpressionDYNC1LI1 [ NCBI-GEO ]   DYNC1LI1 [ EBI - ARRAY_EXPRESS ]   DYNC1LI1 [ SEEK ]   DYNC1LI1 [ MEM ]
Gene Expression Viewer (FireBrowse)DYNC1LI1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51143
GTEX Portal (Tissue expression)DYNC1LI1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6G9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6G9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6G9
Splice isoforms : SwissVarQ9Y6G9
PhosPhoSitePlusQ9Y6G9
Domains : Interpro (EBI)Dynein1_light_intermed_chain    Dynein_light_int_chain    P-loop_NTPase   
Domain families : Pfam (Sanger)DLIC (PF05783)   
Domain families : Pfam (NCBI)pfam05783   
Conserved Domain (NCBI)DYNC1LI1
DMDM Disease mutations51143
Blocks (Seattle)DYNC1LI1
SuperfamilyQ9Y6G9
Human Protein AtlasENSG00000144635
Peptide AtlasQ9Y6G9
HPRD10917
IPIIPI00007675   IPI00909015   IPI00927867   IPI00796377   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6G9
IntAct (EBI)Q9Y6G9
FunCoupENSG00000144635
BioGRIDDYNC1LI1
STRING (EMBL)DYNC1LI1
ZODIACDYNC1LI1
Ontologies - Pathways
QuickGOQ9Y6G9
Ontology : AmiGOmicrotubule cytoskeleton organization  kinetochore  condensed chromosome kinetochore  spindle pole  RNA binding  microtubule motor activity  protein binding  ATP binding  GTP binding  centrosome  cytosol  cytoplasmic dynein complex  microtubule  plasma membrane  ER to Golgi vesicle-mediated transport  microtubule-based movement  cell cycle  membrane  viral process  GDP binding  antigen processing and presentation of exogenous peptide antigen via MHC class II  secretory granule membrane  neutrophil degranulation  dynein heavy chain binding  cell division  positive regulation of mitotic cell cycle spindle assembly checkpoint  ficolin-1-rich granule membrane  
Ontology : EGO-EBImicrotubule cytoskeleton organization  kinetochore  condensed chromosome kinetochore  spindle pole  RNA binding  microtubule motor activity  protein binding  ATP binding  GTP binding  centrosome  cytosol  cytoplasmic dynein complex  microtubule  plasma membrane  ER to Golgi vesicle-mediated transport  microtubule-based movement  cell cycle  membrane  viral process  GDP binding  antigen processing and presentation of exogenous peptide antigen via MHC class II  secretory granule membrane  neutrophil degranulation  dynein heavy chain binding  cell division  positive regulation of mitotic cell cycle spindle assembly checkpoint  ficolin-1-rich granule membrane  
Pathways : KEGGPhagosome    Vasopressin-regulated water reabsorption    Salmonella infection   
NDEx NetworkDYNC1LI1
Atlas of Cancer Signalling NetworkDYNC1LI1
Wikipedia pathwaysDYNC1LI1
Orthology - Evolution
OrthoDB51143
GeneTree (enSembl)ENSG00000144635
Phylogenetic Trees/Animal Genes : TreeFamDYNC1LI1
HOVERGENQ9Y6G9
HOGENOMQ9Y6G9
Homologs : HomoloGeneDYNC1LI1
Homology/Alignments : Family Browser (UCSC)DYNC1LI1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDYNC1LI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DYNC1LI1
dbVarDYNC1LI1
ClinVarDYNC1LI1
1000_GenomesDYNC1LI1 
Exome Variant ServerDYNC1LI1
ExAC (Exome Aggregation Consortium)DYNC1LI1 (select the gene name)
Genetic variants : HAPMAP51143
Genomic Variants (DGV)DYNC1LI1 [DGVbeta]
DECIPHERDYNC1LI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDYNC1LI1 
Mutations
ICGC Data PortalDYNC1LI1 
TCGA Data PortalDYNC1LI1 
Broad Tumor PortalDYNC1LI1
OASIS PortalDYNC1LI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDYNC1LI1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDYNC1LI1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DYNC1LI1
DgiDB (Drug Gene Interaction Database)DYNC1LI1
DoCM (Curated mutations)DYNC1LI1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DYNC1LI1 (select a term)
intoGenDYNC1LI1
Cancer3DDYNC1LI1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615890   
Orphanet
MedgenDYNC1LI1
Genetic Testing Registry DYNC1LI1
NextProtQ9Y6G9 [Medical]
TSGene51143
GENETestsDYNC1LI1
Target ValidationDYNC1LI1
Huge Navigator DYNC1LI1 [HugePedia]
snp3D : Map Gene to Disease51143
BioCentury BCIQDYNC1LI1
ClinGenDYNC1LI1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51143
Chemical/Pharm GKB GenePA38670
Clinical trialDYNC1LI1
Miscellaneous
canSAR (ICR)DYNC1LI1 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDYNC1LI1
EVEXDYNC1LI1
GoPubMedDYNC1LI1
iHOPDYNC1LI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Wed Jun 7 15:46:38 CEST 2017

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