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DYNC1LI2 (dynein cytoplasmic 1 light intermediate chain 2)

Identity

Alias_namesDNCLI2
dynein, cytoplasmic, light intermediate polypeptide 2
Other aliasLIC2
HGNC (Hugo) DYNC1LI2
LocusID (NCBI) 1783
Atlas_Id 62690
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 66720896 and ends at 66751622 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DYNC1LI2 (16q22.1) / DYNC1LI2 (16q22.1)DYNC1LI2 (16q22.1) / PLXNA2 (1q32.2)DYNC1LI2 (16q22.1) / SYCP1 (1p13.2)
ZNF611 (19q13.41) / DYNC1LI2 (16q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DYNC1LI2   2966
Cards
Entrez_Gene (NCBI)DYNC1LI2  1783  dynein cytoplasmic 1 light intermediate chain 2
AliasesDNCLI2; LIC2
GeneCards (Weizmann)DYNC1LI2
Ensembl hg19 (Hinxton)ENSG00000135720 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135720 [Gene_View]  chr16:66720896-66751622 [Contig_View]  DYNC1LI2 [Vega]
ICGC DataPortalENSG00000135720
TCGA cBioPortalDYNC1LI2
AceView (NCBI)DYNC1LI2
Genatlas (Paris)DYNC1LI2
WikiGenes1783
SOURCE (Princeton)DYNC1LI2
Genetics Home Reference (NIH)DYNC1LI2
Genomic and cartography
GoldenPath hg38 (UCSC)DYNC1LI2  -     chr16:66720896-66751622 -  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DYNC1LI2  -     16q22.1   [Description]    (hg19-Feb_2009)
EnsemblDYNC1LI2 - 16q22.1 [CytoView hg19]  DYNC1LI2 - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBIDYNC1LI2 [Mapview hg19]  DYNC1LI2 [Mapview hg38]
OMIM611406   
Gene and transcription
Genbank (Entrez)AF035812 AK024863 AK095237 AK291766 AK295049
RefSeq transcript (Entrez)NM_001286157 NM_001323955 NM_006141
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DYNC1LI2
Cluster EST : UnigeneHs.369068 [ NCBI ]
CGAP (NCI)Hs.369068
Alternative Splicing GalleryENSG00000135720
Gene ExpressionDYNC1LI2 [ NCBI-GEO ]   DYNC1LI2 [ EBI - ARRAY_EXPRESS ]   DYNC1LI2 [ SEEK ]   DYNC1LI2 [ MEM ]
Gene Expression Viewer (FireBrowse)DYNC1LI2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1783
GTEX Portal (Tissue expression)DYNC1LI2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43237   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43237  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43237
Splice isoforms : SwissVarO43237
PhosPhoSitePlusO43237
Domains : Interpro (EBI)Dynein1_light_intermed_chain    Dynein_light_int_chain    P-loop_NTPase   
Domain families : Pfam (Sanger)DLIC (PF05783)   
Domain families : Pfam (NCBI)pfam05783   
Conserved Domain (NCBI)DYNC1LI2
DMDM Disease mutations1783
Blocks (Seattle)DYNC1LI2
SuperfamilyO43237
Human Protein AtlasENSG00000135720
Peptide AtlasO43237
HPRD09923
IPIIPI00011592   IPI00909090   IPI00909455   IPI00470463   
Protein Interaction databases
DIP (DOE-UCLA)O43237
IntAct (EBI)O43237
FunCoupENSG00000135720
BioGRIDDYNC1LI2
STRING (EMBL)DYNC1LI2
ZODIACDYNC1LI2
Ontologies - Pathways
QuickGOO43237
Ontology : AmiGOmicrotubule cytoskeleton organization  microtubule motor activity  ATP binding  centrosome  cytosol  cytoplasmic dynein complex  microtubule  ER to Golgi vesicle-mediated transport  microtubule-based movement  membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  dynein heavy chain binding  centrosome localization  
Ontology : EGO-EBImicrotubule cytoskeleton organization  microtubule motor activity  ATP binding  centrosome  cytosol  cytoplasmic dynein complex  microtubule  ER to Golgi vesicle-mediated transport  microtubule-based movement  membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  dynein heavy chain binding  centrosome localization  
Pathways : KEGGPhagosome    Vasopressin-regulated water reabsorption    Salmonella infection   
NDEx NetworkDYNC1LI2
Atlas of Cancer Signalling NetworkDYNC1LI2
Wikipedia pathwaysDYNC1LI2
Orthology - Evolution
OrthoDB1783
GeneTree (enSembl)ENSG00000135720
Phylogenetic Trees/Animal Genes : TreeFamDYNC1LI2
HOVERGENO43237
HOGENOMO43237
Homologs : HomoloGeneDYNC1LI2
Homology/Alignments : Family Browser (UCSC)DYNC1LI2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDYNC1LI2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DYNC1LI2
dbVarDYNC1LI2
ClinVarDYNC1LI2
1000_GenomesDYNC1LI2 
Exome Variant ServerDYNC1LI2
ExAC (Exome Aggregation Consortium)DYNC1LI2 (select the gene name)
Genetic variants : HAPMAP1783
Genomic Variants (DGV)DYNC1LI2 [DGVbeta]
DECIPHERDYNC1LI2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDYNC1LI2 
Mutations
ICGC Data PortalDYNC1LI2 
TCGA Data PortalDYNC1LI2 
Broad Tumor PortalDYNC1LI2
OASIS PortalDYNC1LI2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDYNC1LI2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDYNC1LI2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DYNC1LI2
DgiDB (Drug Gene Interaction Database)DYNC1LI2
DoCM (Curated mutations)DYNC1LI2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DYNC1LI2 (select a term)
intoGenDYNC1LI2
Cancer3DDYNC1LI2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611406   
Orphanet
MedgenDYNC1LI2
Genetic Testing Registry DYNC1LI2
NextProtO43237 [Medical]
TSGene1783
GENETestsDYNC1LI2
Target ValidationDYNC1LI2
Huge Navigator DYNC1LI2 [HugePedia]
snp3D : Map Gene to Disease1783
BioCentury BCIQDYNC1LI2
ClinGenDYNC1LI2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1783
Chemical/Pharm GKB GenePA27438
Clinical trialDYNC1LI2
Miscellaneous
canSAR (ICR)DYNC1LI2 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDYNC1LI2
EVEXDYNC1LI2
GoPubMedDYNC1LI2
iHOPDYNC1LI2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:46:38 CEST 2017

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