Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DYNC2LI1 (dynein cytoplasmic 2 light intermediate chain 1)

Identity

Alias_symbol (synonym)D2LIC
LIC3
CGI-60
DKFZP564A033
Other alias
HGNC (Hugo) DYNC2LI1
LocusID (NCBI) 51626
Atlas_Id 62691
Location 2p21  [Link to chromosome band 2p21]
Location_base_pair Starts at 43774039 and ends at 43810010 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARFGEF3 (6q23.3) / DYNC2LI1 (2p21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DYNC2LI1   24595
Cards
Entrez_Gene (NCBI)DYNC2LI1  51626  dynein cytoplasmic 2 light intermediate chain 1
AliasesCGI-60; D2LIC; LIC3
GeneCards (Weizmann)DYNC2LI1
Ensembl hg19 (Hinxton)ENSG00000138036 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138036 [Gene_View]  chr2:43774039-43810010 [Contig_View]  DYNC2LI1 [Vega]
ICGC DataPortalENSG00000138036
TCGA cBioPortalDYNC2LI1
AceView (NCBI)DYNC2LI1
Genatlas (Paris)DYNC2LI1
WikiGenes51626
SOURCE (Princeton)DYNC2LI1
Genetics Home Reference (NIH)DYNC2LI1
Genomic and cartography
GoldenPath hg38 (UCSC)DYNC2LI1  -     chr2:43774039-43810010 +  2p21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DYNC2LI1  -     2p21   [Description]    (hg19-Feb_2009)
EnsemblDYNC2LI1 - 2p21 [CytoView hg19]  DYNC2LI1 - 2p21 [CytoView hg38]
Mapping of homologs : NCBIDYNC2LI1 [Mapview hg19]  DYNC2LI1 [Mapview hg38]
OMIM617083   617088   
Gene and transcription
Genbank (Entrez)AF151818 AK074206 AK223432 AK301489 AL050006
RefSeq transcript (Entrez)NM_001012665 NM_001193464 NM_001348912 NM_001348913 NM_015522 NM_016008
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DYNC2LI1
Cluster EST : UnigeneHs.371597 [ NCBI ]
CGAP (NCI)Hs.371597
Alternative Splicing GalleryENSG00000138036
Gene ExpressionDYNC2LI1 [ NCBI-GEO ]   DYNC2LI1 [ EBI - ARRAY_EXPRESS ]   DYNC2LI1 [ SEEK ]   DYNC2LI1 [ MEM ]
Gene Expression Viewer (FireBrowse)DYNC2LI1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51626
GTEX Portal (Tissue expression)DYNC2LI1
Human Protein AtlasENSG00000138036-DYNC2LI1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCX1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCX1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCX1
Splice isoforms : SwissVarQ8TCX1
PhosPhoSitePlusQ8TCX1
Domains : Interpro (EBI)Dynein_light_int_chain    P-loop_NTPase   
Domain families : Pfam (Sanger)DLIC (PF05783)   
Domain families : Pfam (NCBI)pfam05783   
Conserved Domain (NCBI)DYNC2LI1
DMDM Disease mutations51626
Blocks (Seattle)DYNC2LI1
SuperfamilyQ8TCX1
Human Protein Atlas [tissue]ENSG00000138036-DYNC2LI1 [tissue]
Peptide AtlasQ8TCX1
HPRD13116
IPIIPI00885209   IPI00465426   IPI00554555   IPI00059632   IPI00217241   IPI01010693   IPI00973769   IPI00973823   IPI00974150   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCX1
IntAct (EBI)Q8TCX1
FunCoupENSG00000138036
BioGRIDDYNC2LI1
STRING (EMBL)DYNC2LI1
ZODIACDYNC2LI1
Ontologies - Pathways
QuickGOQ8TCX1
Ontology : AmiGOprotein binding  cytoplasm  centrosome  cytoplasmic dynein complex  cytoplasmic dynein complex  cytoplasmic microtubule  cilium  cilium  axoneme  axoneme  determination of left/right symmetry  ATP-dependent microtubule motor activity, minus-end-directed  intraciliary transport particle  motile cilium  intraciliary transport involved in cilium assembly  intraciliary transport involved in cilium assembly  ciliary transition zone  ciliary basal body  ciliary basal body  ciliary basal body  apical part of cell  dynein heavy chain binding  cilium assembly  ciliary tip  regulation of cilium assembly  
Ontology : EGO-EBIprotein binding  cytoplasm  centrosome  cytoplasmic dynein complex  cytoplasmic dynein complex  cytoplasmic microtubule  cilium  cilium  axoneme  axoneme  determination of left/right symmetry  ATP-dependent microtubule motor activity, minus-end-directed  intraciliary transport particle  motile cilium  intraciliary transport involved in cilium assembly  intraciliary transport involved in cilium assembly  ciliary transition zone  ciliary basal body  ciliary basal body  ciliary basal body  apical part of cell  dynein heavy chain binding  cilium assembly  ciliary tip  regulation of cilium assembly  
Pathways : KEGGVasopressin-regulated water reabsorption   
NDEx NetworkDYNC2LI1
Atlas of Cancer Signalling NetworkDYNC2LI1
Wikipedia pathwaysDYNC2LI1
Orthology - Evolution
OrthoDB51626
GeneTree (enSembl)ENSG00000138036
Phylogenetic Trees/Animal Genes : TreeFamDYNC2LI1
HOVERGENQ8TCX1
HOGENOMQ8TCX1
Homologs : HomoloGeneDYNC2LI1
Homology/Alignments : Family Browser (UCSC)DYNC2LI1
Gene fusions - Rearrangements
Fusion: Tumor Portal DYNC2LI1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDYNC2LI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DYNC2LI1
dbVarDYNC2LI1
ClinVarDYNC2LI1
1000_GenomesDYNC2LI1 
Exome Variant ServerDYNC2LI1
ExAC (Exome Aggregation Consortium)ENSG00000138036
GNOMAD BrowserENSG00000138036
Genetic variants : HAPMAP51626
Genomic Variants (DGV)DYNC2LI1 [DGVbeta]
DECIPHERDYNC2LI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDYNC2LI1 
Mutations
ICGC Data PortalDYNC2LI1 
TCGA Data PortalDYNC2LI1 
Broad Tumor PortalDYNC2LI1
OASIS PortalDYNC2LI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDYNC2LI1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDYNC2LI1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DYNC2LI1
DgiDB (Drug Gene Interaction Database)DYNC2LI1
DoCM (Curated mutations)DYNC2LI1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DYNC2LI1 (select a term)
intoGenDYNC2LI1
Cancer3DDYNC2LI1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617083    617088   
Orphanet
MedgenDYNC2LI1
Genetic Testing Registry DYNC2LI1
NextProtQ8TCX1 [Medical]
TSGene51626
GENETestsDYNC2LI1
Target ValidationDYNC2LI1
Huge Navigator DYNC2LI1 [HugePedia]
snp3D : Map Gene to Disease51626
BioCentury BCIQDYNC2LI1
ClinGenDYNC2LI1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51626
Chemical/Pharm GKB GenePA142671919
Clinical trialDYNC2LI1
Miscellaneous
canSAR (ICR)DYNC2LI1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDYNC2LI1
EVEXDYNC2LI1
GoPubMedDYNC2LI1
iHOPDYNC2LI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:45:19 CET 2017

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