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DYNLL2 (dynein, light chain, LC8-type 2)

Identity

Alias_symbol (synonym)MGC17810
Dlc2
DNCL1B
RSPH22
Other alias
HGNC (Hugo) DYNLL2
LocusID (NCBI) 140735
Atlas_Id 62693
Location 17q22  [Link to chromosome band 17q22]
Location_base_pair Starts at 56160780 and ends at 56167618 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DYNLL2 (17q22) / SEPT4 (17q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DYNLL2   24596
Cards
Entrez_Gene (NCBI)DYNLL2  140735  dynein, light chain, LC8-type 2
AliasesDNCL1B; Dlc2; RSPH22
GeneCards (Weizmann)DYNLL2
Ensembl hg19 (Hinxton) [Gene_View]  chr17:56160780-56167618 [Contig_View]  DYNLL2 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr17:56160780-56167618 [Contig_View]  DYNLL2 [Vega]
TCGA cBioPortalDYNLL2
AceView (NCBI)DYNLL2
Genatlas (Paris)DYNLL2
WikiGenes140735
SOURCE (Princeton)DYNLL2
Genetics Home Reference (NIH)DYNLL2
Genomic and cartography
GoldenPath hg19 (UCSC)DYNLL2  -     chr17:56160780-56167618 +  17q22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DYNLL2  -     17q22   [Description]    (hg38-Dec_2013)
EnsemblDYNLL2 - 17q22 [CytoView hg19]  DYNLL2 - 17q22 [CytoView hg38]
Mapping of homologs : NCBIDYNLL2 [Mapview hg19]  DYNLL2 [Mapview hg38]
OMIM608942   
Gene and transcription
Genbank (Entrez)AF086304 AF112997 AK312125 BC010744 BF528423
RefSeq transcript (Entrez)NM_080677
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)DYNLL2
Cluster EST : UnigeneHs.720595 [ NCBI ]
CGAP (NCI)Hs.720595
Gene ExpressionDYNLL2 [ NCBI-GEO ]   DYNLL2 [ EBI - ARRAY_EXPRESS ]   DYNLL2 [ SEEK ]   DYNLL2 [ MEM ]
Gene Expression Viewer (FireBrowse)DYNLL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)140735
GTEX Portal (Tissue expression)DYNLL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96FJ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96FJ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96FJ2
Splice isoforms : SwissVarQ96FJ2
PhosPhoSitePlusQ96FJ2
Domaine pattern : Prosite (Expaxy)DYNEIN_LIGHT_1 (PS01239)   
Domains : Interpro (EBI)Dynein_light_1/2_CS    Dynein_light_chain_typ-1/2   
Domain families : Pfam (Sanger)Dynein_light (PF01221)   
Domain families : Pfam (NCBI)pfam01221   
Conserved Domain (NCBI)DYNLL2
DMDM Disease mutations140735
Blocks (Seattle)DYNLL2
PDB (SRS)2XQQ    3P8M    4D07   
PDB (PDBSum)2XQQ    3P8M    4D07   
PDB (IMB)2XQQ    3P8M    4D07   
PDB (RSDB)2XQQ    3P8M    4D07   
Structural Biology KnowledgeBase2XQQ    3P8M    4D07   
SCOP (Structural Classification of Proteins)2XQQ    3P8M    4D07   
CATH (Classification of proteins structures)2XQQ    3P8M    4D07   
SuperfamilyQ96FJ2
Peptide AtlasQ96FJ2
HPRD06489
IPIIPI00062037   
Protein Interaction databases
DIP (DOE-UCLA)Q96FJ2
IntAct (EBI)Q96FJ2
BioGRIDDYNLL2
STRING (EMBL)DYNLL2
ZODIACDYNLL2
Ontologies - Pathways
QuickGOQ96FJ2
Ontology : AmiGOmotor activity  protein binding  nucleus  centrosome  cytosol  microtubule  plasma membrane  transport  apoptotic process  organelle organization  microtubule-based process  synaptic target recognition  cytoskeletal protein binding  metabolic process  programmed cell death  membrane  myosin complex  antigen processing and presentation of exogenous peptide antigen via MHC class II  dynein complex  primary cilium  intrinsic apoptotic signaling pathway  ciliary tip  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  
Ontology : EGO-EBImotor activity  protein binding  nucleus  centrosome  cytosol  microtubule  plasma membrane  transport  apoptotic process  organelle organization  microtubule-based process  synaptic target recognition  cytoskeletal protein binding  metabolic process  programmed cell death  membrane  myosin complex  antigen processing and presentation of exogenous peptide antigen via MHC class II  dynein complex  primary cilium  intrinsic apoptotic signaling pathway  ciliary tip  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  
Pathways : KEGGVasopressin-regulated water reabsorption   
NDEx NetworkDYNLL2
Atlas of Cancer Signalling NetworkDYNLL2
Wikipedia pathwaysDYNLL2
Orthology - Evolution
OrthoDB140735
Phylogenetic Trees/Animal Genes : TreeFamDYNLL2
HOVERGENQ96FJ2
HOGENOMQ96FJ2
Homologs : HomoloGeneDYNLL2
Homology/Alignments : Family Browser (UCSC)DYNLL2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDYNLL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DYNLL2
dbVarDYNLL2
ClinVarDYNLL2
1000_GenomesDYNLL2 
Exome Variant ServerDYNLL2
ExAC (Exome Aggregation Consortium)DYNLL2 (select the gene name)
Genetic variants : HAPMAP140735
Genomic Variants (DGV)DYNLL2 [DGVbeta]
DECIPHER (Syndromes)17:56160780-56167618  
CONAN: Copy Number AnalysisDYNLL2 
Mutations
ICGC Data PortalDYNLL2 
TCGA Data PortalDYNLL2 
Broad Tumor PortalDYNLL2
OASIS PortalDYNLL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDYNLL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDYNLL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DYNLL2
DgiDB (Drug Gene Interaction Database)DYNLL2
DoCM (Curated mutations)DYNLL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DYNLL2 (select a term)
intoGenDYNLL2
Cancer3DDYNLL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608942   
Orphanet
MedgenDYNLL2
Genetic Testing Registry DYNLL2
NextProtQ96FJ2 [Medical]
TSGene140735
GENETestsDYNLL2
Huge Navigator DYNLL2 [HugePedia]
snp3D : Map Gene to Disease140735
BioCentury BCIQDYNLL2
ClinGenDYNLL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD140735
Chemical/Pharm GKB GenePA142671920
Clinical trialDYNLL2
Miscellaneous
canSAR (ICR)DYNLL2 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDYNLL2
EVEXDYNLL2
GoPubMedDYNLL2
iHOPDYNLL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 12:02:24 CET 2017

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