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DYNLRB2 (dynein light chain roadblock-type 2)

Identity

Alias_namesDNCL2B
dynein
Alias_symbol (synonym)DNLC2B
ROBLD2
Other alias
HGNC (Hugo) DYNLRB2
LocusID (NCBI) 83657
Atlas_Id 45985
Location 16q23.2  [Link to chromosome band 16q23]
Location_base_pair Starts at 80540952 and ends at 80550809 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CMIP (16q23.2) / DYNLRB2 (16q23.2)DYNLRB2 (16q23.2) / DYNLRB2 (16q23.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DYNLRB2   15467
Cards
Entrez_Gene (NCBI)DYNLRB2  83657  dynein light chain roadblock-type 2
AliasesDNCL2B; DNLC2B; ROBLD2
GeneCards (Weizmann)DYNLRB2
Ensembl hg19 (Hinxton)ENSG00000168589 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168589 [Gene_View]  ENSG00000168589 [Sequence]  chr16:80540952-80550809 [Contig_View]  DYNLRB2 [Vega]
ICGC DataPortalENSG00000168589
TCGA cBioPortalDYNLRB2
AceView (NCBI)DYNLRB2
Genatlas (Paris)DYNLRB2
WikiGenes83657
SOURCE (Princeton)DYNLRB2
Genetics Home Reference (NIH)DYNLRB2
Genomic and cartography
GoldenPath hg38 (UCSC)DYNLRB2  -     chr16:80540952-80550809 +  16q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DYNLRB2  -     16q23.2   [Description]    (hg19-Feb_2009)
EnsemblDYNLRB2 - 16q23.2 [CytoView hg19]  DYNLRB2 - 16q23.2 [CytoView hg38]
Mapping of homologs : NCBIDYNLRB2 [Mapview hg19]  DYNLRB2 [Mapview hg38]
OMIM607168   
Gene and transcription
Genbank (Entrez)AF125108 BC035232 BC054892 CD676360 DB458006
RefSeq transcript (Entrez)NM_001305017 NM_130897
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DYNLRB2
Cluster EST : UnigeneHs.98849 [ NCBI ]
CGAP (NCI)Hs.98849
Alternative Splicing GalleryENSG00000168589
Gene ExpressionDYNLRB2 [ NCBI-GEO ]   DYNLRB2 [ EBI - ARRAY_EXPRESS ]   DYNLRB2 [ SEEK ]   DYNLRB2 [ MEM ]
Gene Expression Viewer (FireBrowse)DYNLRB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83657
GTEX Portal (Tissue expression)DYNLRB2
Human Protein AtlasENSG00000168589-DYNLRB2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TF09   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TF09  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TF09
Splice isoforms : SwissVarQ8TF09
PhosPhoSitePlusQ8TF09
Domains : Interpro (EBI)DYNLRB1/2    Roadblock/LAMTOR2_dom   
Domain families : Pfam (Sanger)Robl_LC7 (PF03259)   
Domain families : Pfam (NCBI)pfam03259   
Domain families : Smart (EMBL)Robl_LC7 (SM00960)  
Conserved Domain (NCBI)DYNLRB2
DMDM Disease mutations83657
Blocks (Seattle)DYNLRB2
SuperfamilyQ8TF09
Human Protein Atlas [tissue]ENSG00000168589-DYNLRB2 [tissue]
Peptide AtlasQ8TF09
HPRD06204
IPIIPI00178188   IPI00385120   
Protein Interaction databases
DIP (DOE-UCLA)Q8TF09
IntAct (EBI)Q8TF09
FunCoupENSG00000168589
BioGRIDDYNLRB2
STRING (EMBL)DYNLRB2
ZODIACDYNLRB2
Ontologies - Pathways
QuickGOQ8TF09
Ontology : AmiGOmicrotubule motor activity  cytoplasmic dynein complex  cytoplasmic dynein complex  cytoplasmic dynein complex  microtubule  cilium  microtubule-based movement  microtubule-based movement  intraciliary transport involved in cilium assembly  outer dynein arm  dynein intermediate chain binding  ciliary tip  
Ontology : EGO-EBImicrotubule motor activity  cytoplasmic dynein complex  cytoplasmic dynein complex  cytoplasmic dynein complex  microtubule  cilium  microtubule-based movement  microtubule-based movement  intraciliary transport involved in cilium assembly  outer dynein arm  dynein intermediate chain binding  ciliary tip  
NDEx NetworkDYNLRB2
Atlas of Cancer Signalling NetworkDYNLRB2
Wikipedia pathwaysDYNLRB2
Orthology - Evolution
OrthoDB83657
GeneTree (enSembl)ENSG00000168589
Phylogenetic Trees/Animal Genes : TreeFamDYNLRB2
HOVERGENQ8TF09
HOGENOMQ8TF09
Homologs : HomoloGeneDYNLRB2
Homology/Alignments : Family Browser (UCSC)DYNLRB2
Gene fusions - Rearrangements
Fusion : QuiverDYNLRB2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDYNLRB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DYNLRB2
dbVarDYNLRB2
ClinVarDYNLRB2
1000_GenomesDYNLRB2 
Exome Variant ServerDYNLRB2
ExAC (Exome Aggregation Consortium)ENSG00000168589
GNOMAD BrowserENSG00000168589
Varsome BrowserDYNLRB2
Genetic variants : HAPMAP83657
Genomic Variants (DGV)DYNLRB2 [DGVbeta]
DECIPHERDYNLRB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDYNLRB2 
Mutations
ICGC Data PortalDYNLRB2 
TCGA Data PortalDYNLRB2 
Broad Tumor PortalDYNLRB2
OASIS PortalDYNLRB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDYNLRB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDYNLRB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DYNLRB2
DgiDB (Drug Gene Interaction Database)DYNLRB2
DoCM (Curated mutations)DYNLRB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DYNLRB2 (select a term)
intoGenDYNLRB2
Cancer3DDYNLRB2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607168   
Orphanet
DisGeNETDYNLRB2
MedgenDYNLRB2
Genetic Testing Registry DYNLRB2
NextProtQ8TF09 [Medical]
TSGene83657
GENETestsDYNLRB2
Target ValidationDYNLRB2
Huge Navigator DYNLRB2 [HugePedia]
snp3D : Map Gene to Disease83657
BioCentury BCIQDYNLRB2
ClinGenDYNLRB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83657
Chemical/Pharm GKB GenePA27437
Clinical trialDYNLRB2
Miscellaneous
canSAR (ICR)DYNLRB2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDYNLRB2
EVEXDYNLRB2
GoPubMedDYNLRB2
iHOPDYNLRB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:03:39 CET 2018

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