Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DYX1C1 (dyslexia susceptibility 1 candidate 1)

Identity

Alias_namesaxonemal
assembly factor 4
Alias_symbol (synonym)EKN1
FLJ37882
CILD25
DNAAF4
Other aliasDYX1
DYXC1
RD
HGNC (Hugo) DYX1C1
LocusID (NCBI) 161582
Atlas_Id 50914
Location 15q21.3  [Link to chromosome band 15q21]
Location_base_pair Starts at 55722506 and ends at 55800432 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DYX1C1 (15q21.3) / RFX7 (15q21.3)DYX1C1 15q21.3 / RFX7 15q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DYX1C1   21493
Cards
Entrez_Gene (NCBI)DYX1C1  161582  dyslexia susceptibility 1 candidate 1
AliasesCILD25; DNAAF4; DYX1; DYXC1; 
EKN1; RD
GeneCards (Weizmann)DYX1C1
Ensembl hg19 (Hinxton)ENSG00000256061 [Gene_View]  chr15:55722506-55800432 [Contig_View]  DYX1C1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000256061 [Gene_View]  chr15:55722506-55800432 [Contig_View]  DYX1C1 [Vega]
ICGC DataPortalENSG00000256061
TCGA cBioPortalDYX1C1
AceView (NCBI)DYX1C1
Genatlas (Paris)DYX1C1
WikiGenes161582
SOURCE (Princeton)DYX1C1
Genetics Home Reference (NIH)DYX1C1
Genomic and cartography
GoldenPath hg19 (UCSC)DYX1C1  -     chr15:55722506-55800432 -  15q21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DYX1C1  -     15q21.3   [Description]    (hg38-Dec_2013)
EnsemblDYX1C1 - 15q21.3 [CytoView hg19]  DYX1C1 - 15q21.3 [CytoView hg38]
Mapping of homologs : NCBIDYX1C1 [Mapview hg19]  DYX1C1 [Mapview hg38]
OMIM127700   608706   615482   
Gene and transcription
Genbank (Entrez)AF337549 AK095201 AK302316 BC017392 BC062564
RefSeq transcript (Entrez)NM_001033559 NM_001033560 NM_130810
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_021213 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)DYX1C1
Cluster EST : UnigeneHs.126403 [ NCBI ]
CGAP (NCI)Hs.126403
Alternative Splicing GalleryENSG00000256061
Gene ExpressionDYX1C1 [ NCBI-GEO ]   DYX1C1 [ EBI - ARRAY_EXPRESS ]   DYX1C1 [ SEEK ]   DYX1C1 [ MEM ]
Gene Expression Viewer (FireBrowse)DYX1C1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)161582
GTEX Portal (Tissue expression)DYX1C1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WXU2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WXU2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WXU2
Splice isoforms : SwissVarQ8WXU2
PhosPhoSitePlusQ8WXU2
Domaine pattern : Prosite (Expaxy)CS (PS51203)    TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)CS_dom    HSP20-like_chaperone    TPR-contain_dom    TPR-like_helical_dom    TPR_1    TPR_repeat   
Domain families : Pfam (Sanger)CS (PF04969)    TPR_1 (PF00515)    TPR_11 (PF13414)   
Domain families : Pfam (NCBI)pfam04969    pfam00515    pfam13414   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)DYX1C1
DMDM Disease mutations161582
Blocks (Seattle)DYX1C1
SuperfamilyQ8WXU2
Human Protein AtlasENSG00000256061
Peptide AtlasQ8WXU2
HPRD10568
IPIIPI00103616   IPI00472826   IPI00166250   IPI00909491   IPI00980815   IPI00974534   
Protein Interaction databases
DIP (DOE-UCLA)Q8WXU2
IntAct (EBI)Q8WXU2
FunCoupENSG00000256061
BioGRIDDYX1C1
STRING (EMBL)DYX1C1
ZODIACDYX1C1
Ontologies - Pathways
QuickGOQ8WXU2
Ontology : AmiGOneuron migration  cilium movement  protein binding  nucleus  cytoplasm  plasma membrane  determination of left/right symmetry  estrogen receptor binding  regulation of intracellular estrogen receptor signaling pathway  outer dynein arm assembly  inner dynein arm assembly  regulation of proteasomal protein catabolic process  
Ontology : EGO-EBIneuron migration  cilium movement  protein binding  nucleus  cytoplasm  plasma membrane  determination of left/right symmetry  estrogen receptor binding  regulation of intracellular estrogen receptor signaling pathway  outer dynein arm assembly  inner dynein arm assembly  regulation of proteasomal protein catabolic process  
NDEx NetworkDYX1C1
Atlas of Cancer Signalling NetworkDYX1C1
Wikipedia pathwaysDYX1C1
Orthology - Evolution
OrthoDB161582
GeneTree (enSembl)ENSG00000256061
Phylogenetic Trees/Animal Genes : TreeFamDYX1C1
HOVERGENQ8WXU2
HOGENOMQ8WXU2
Homologs : HomoloGeneDYX1C1
Homology/Alignments : Family Browser (UCSC)DYX1C1
Gene fusions - Rearrangements
Fusion : MitelmanDYX1C1/RFX7 [15q21.3/15q21.3]  
Fusion: TCGADYX1C1 15q21.3 RFX7 15q21.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDYX1C1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DYX1C1
dbVarDYX1C1
ClinVarDYX1C1
1000_GenomesDYX1C1 
Exome Variant ServerDYX1C1
ExAC (Exome Aggregation Consortium)DYX1C1 (select the gene name)
Genetic variants : HAPMAP161582
Genomic Variants (DGV)DYX1C1 [DGVbeta]
DECIPHER (Syndromes)15:55722506-55800432  ENSG00000256061
CONAN: Copy Number AnalysisDYX1C1 
Mutations
ICGC Data PortalDYX1C1 
TCGA Data PortalDYX1C1 
Broad Tumor PortalDYX1C1
OASIS PortalDYX1C1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDYX1C1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDYX1C1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DYX1C1
DgiDB (Drug Gene Interaction Database)DYX1C1
DoCM (Curated mutations)DYX1C1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DYX1C1 (select a term)
intoGenDYX1C1
Cancer3DDYX1C1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM127700    608706    615482   
Orphanet665   
MedgenDYX1C1
Genetic Testing Registry DYX1C1
NextProtQ8WXU2 [Medical]
TSGene161582
GENETestsDYX1C1
Huge Navigator DYX1C1 [HugePedia]
snp3D : Map Gene to Disease161582
BioCentury BCIQDYX1C1
ClinGenDYX1C1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD161582
Chemical/Pharm GKB GenePA134870600
Clinical trialDYX1C1
Miscellaneous
canSAR (ICR)DYX1C1 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDYX1C1
EVEXDYX1C1
GoPubMedDYX1C1
iHOPDYX1C1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 13:04:07 CET 2017

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