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E2F5 (E2F transcription factor 5)

Identity

Alias_namesE2F transcription factor 5
Other aliasE2F-5
HGNC (Hugo) E2F5
LocusID (NCBI) 1875
Atlas_Id 40386
Location 8q21.2  [Link to chromosome band 8q21]
Location_base_pair Starts at 85177384 and ends at 85214521 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
E2F5 (8q21.2) / BCL11A (2p16.1)E2F5 (8q21.2) / E2F5 (8q21.2)E2F5 (8q21.2) / PDE4DIP (1q21.1)
USP40 (2q37.1) / E2F5 (8q21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)E2F5   3119
Cards
Entrez_Gene (NCBI)E2F5  1875  E2F transcription factor 5
AliasesE2F-5
GeneCards (Weizmann)E2F5
Ensembl hg19 (Hinxton)ENSG00000133740 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133740 [Gene_View]  chr8:85177384-85214521 [Contig_View]  E2F5 [Vega]
ICGC DataPortalENSG00000133740
TCGA cBioPortalE2F5
AceView (NCBI)E2F5
Genatlas (Paris)E2F5
WikiGenes1875
SOURCE (Princeton)E2F5
Genetics Home Reference (NIH)E2F5
Genomic and cartography
GoldenPath hg38 (UCSC)E2F5  -     chr8:85177384-85214521 +  8q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)E2F5  -     8q21.2   [Description]    (hg19-Feb_2009)
EnsemblE2F5 - 8q21.2 [CytoView hg19]  E2F5 - 8q21.2 [CytoView hg38]
Mapping of homologs : NCBIE2F5 [Mapview hg19]  E2F5 [Mapview hg38]
OMIM600967   
Gene and transcription
Genbank (Entrez)AB209185 AI740797 BC156210 BC172475 BM919591
RefSeq transcript (Entrez)NM_001083588 NM_001083589 NM_001951
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)E2F5
Cluster EST : UnigeneHs.445758 [ NCBI ]
CGAP (NCI)Hs.445758
Alternative Splicing GalleryENSG00000133740
Gene ExpressionE2F5 [ NCBI-GEO ]   E2F5 [ EBI - ARRAY_EXPRESS ]   E2F5 [ SEEK ]   E2F5 [ MEM ]
Gene Expression Viewer (FireBrowse)E2F5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1875
GTEX Portal (Tissue expression)E2F5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15329   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15329  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15329
Splice isoforms : SwissVarQ15329
PhosPhoSitePlusQ15329
Domains : Interpro (EBI)E2F    E2F5    E2F_CC-MB    E2F_WHTH_DNA-bd_dom    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)E2F_CC-MB (PF16421)    E2F_TDP (PF02319)   
Domain families : Pfam (NCBI)pfam16421    pfam02319   
Domain families : Smart (EMBL)E2F_TDP (SM01372)  
Conserved Domain (NCBI)E2F5
DMDM Disease mutations1875
Blocks (Seattle)E2F5
SuperfamilyQ15329
Human Protein AtlasENSG00000133740
Peptide AtlasQ15329
HPRD02983
IPIIPI00940123   IPI00795388   IPI00300501   IPI00845238   IPI00974565   IPI00975797   
Protein Interaction databases
DIP (DOE-UCLA)Q15329
IntAct (EBI)Q15329
FunCoupENSG00000133740
BioGRIDE2F5
STRING (EMBL)E2F5
ZODIACE2F5
Ontologies - Pathways
QuickGOQ15329
Ontology : AmiGOfibrillar center  DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  transcription factor complex  nucleolus  cytoplasm  transcription, DNA-templated  transcription factor binding  animal organ morphogenesis  cell projection organization  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  regulation of cell cycle  
Ontology : EGO-EBIfibrillar center  DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  transcription factor complex  nucleolus  cytoplasm  transcription, DNA-templated  transcription factor binding  animal organ morphogenesis  cell projection organization  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  regulation of cell cycle  
Pathways : KEGGCell cycle    TGF-beta signaling pathway   
NDEx NetworkE2F5
Atlas of Cancer Signalling NetworkE2F5
Wikipedia pathwaysE2F5
Orthology - Evolution
OrthoDB1875
GeneTree (enSembl)ENSG00000133740
Phylogenetic Trees/Animal Genes : TreeFamE2F5
HOVERGENQ15329
HOGENOMQ15329
Homologs : HomoloGeneE2F5
Homology/Alignments : Family Browser (UCSC)E2F5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerE2F5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)E2F5
dbVarE2F5
ClinVarE2F5
1000_GenomesE2F5 
Exome Variant ServerE2F5
ExAC (Exome Aggregation Consortium)E2F5 (select the gene name)
Genetic variants : HAPMAP1875
Genomic Variants (DGV)E2F5 [DGVbeta]
DECIPHERE2F5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisE2F5 
Mutations
ICGC Data PortalE2F5 
TCGA Data PortalE2F5 
Broad Tumor PortalE2F5
OASIS PortalE2F5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICE2F5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDE2F5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch E2F5
DgiDB (Drug Gene Interaction Database)E2F5
DoCM (Curated mutations)E2F5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)E2F5 (select a term)
intoGenE2F5
Cancer3DE2F5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600967   
Orphanet
MedgenE2F5
Genetic Testing Registry E2F5
NextProtQ15329 [Medical]
TSGene1875
GENETestsE2F5
Target ValidationE2F5
Huge Navigator E2F5 [HugePedia]
snp3D : Map Gene to Disease1875
BioCentury BCIQE2F5
ClinGenE2F5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1875
Chemical/Pharm GKB GenePA27577
Clinical trialE2F5
Miscellaneous
canSAR (ICR)E2F5 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineE2F5
EVEXE2F5
GoPubMedE2F5
iHOPE2F5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:00:05 CEST 2017

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