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E2F7 (E2F transcription factor 7)

Identity

Other alias-
HGNC (Hugo) E2F7
LocusID (NCBI) 144455
Atlas_Id 47032
Location 12q21.2  [Link to chromosome band 12q21]
Location_base_pair Starts at 77415026 and ends at 77459360 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
E2F7 (12q21.2) / MDC1 (6p21.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)E2F7   23820
Cards
Entrez_Gene (NCBI)E2F7  144455  E2F transcription factor 7
Aliases
GeneCards (Weizmann)E2F7
Ensembl hg19 (Hinxton)ENSG00000165891 [Gene_View]  chr12:77415026-77459360 [Contig_View]  E2F7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000165891 [Gene_View]  chr12:77415026-77459360 [Contig_View]  E2F7 [Vega]
ICGC DataPortalENSG00000165891
TCGA cBioPortalE2F7
AceView (NCBI)E2F7
Genatlas (Paris)E2F7
WikiGenes144455
SOURCE (Princeton)E2F7
Genetics Home Reference (NIH)E2F7
Genomic and cartography
GoldenPath hg19 (UCSC)E2F7  -     chr12:77415026-77459360 -  12q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)E2F7  -     12q21.2   [Description]    (hg38-Dec_2013)
EnsemblE2F7 - 12q21.2 [CytoView hg19]  E2F7 - 12q21.2 [CytoView hg38]
Mapping of homologs : NCBIE2F7 [Mapview hg19]  E2F7 [Mapview hg38]
OMIM612046   
Gene and transcription
Genbank (Entrez)AI380315 AK023043 AK096316 AK097677 BC016658
RefSeq transcript (Entrez)NM_203394
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)E2F7
Cluster EST : UnigeneHs.416375 [ NCBI ]
CGAP (NCI)Hs.416375
Alternative Splicing GalleryENSG00000165891
Gene ExpressionE2F7 [ NCBI-GEO ]   E2F7 [ EBI - ARRAY_EXPRESS ]   E2F7 [ SEEK ]   E2F7 [ MEM ]
Gene Expression Viewer (FireBrowse)E2F7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)144455
GTEX Portal (Tissue expression)E2F7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AV8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96AV8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96AV8
Splice isoforms : SwissVarQ96AV8
PhosPhoSitePlusQ96AV8
Domains : Interpro (EBI)E2F    E2F_WHTH_DNA-bd_dom    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)E2F_TDP (PF02319)   
Domain families : Pfam (NCBI)pfam02319   
Conserved Domain (NCBI)E2F7
DMDM Disease mutations144455
Blocks (Seattle)E2F7
SuperfamilyQ96AV8
Human Protein AtlasENSG00000165891
Peptide AtlasQ96AV8
HPRD10929
IPIIPI00414604   IPI00854868   IPI00913898   IPI01021896   IPI01022634   IPI01022212   IPI01022956   
Protein Interaction databases
DIP (DOE-UCLA)Q96AV8
IntAct (EBI)Q96AV8
FunCoupENSG00000165891
BioGRIDE2F7
STRING (EMBL)E2F7
ZODIACE2F7
Ontologies - Pathways
QuickGOQ96AV8
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  core promoter binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  placenta development  sprouting angiogenesis  transcription factor activity, sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  protein binding  nucleoplasm  transcription factor complex  transcription, DNA-templated  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  negative regulation of cell proliferation  DNA damage response, signal transduction by p53 class mediator  negative regulation of cytokinesis  positive regulation of DNA endoreduplication  identical protein binding  positive regulation of transcription from RNA polymerase II promoter  trophoblast giant cell differentiation  chorionic trophoblast cell differentiation  hepatocyte differentiation  negative regulation of transcription involved in G1/S transition of mitotic cell cycle  negative regulation of G1/S transition of mitotic cell cycle  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  core promoter binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  placenta development  sprouting angiogenesis  transcription factor activity, sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  protein binding  nucleoplasm  transcription factor complex  transcription, DNA-templated  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  negative regulation of cell proliferation  DNA damage response, signal transduction by p53 class mediator  negative regulation of cytokinesis  positive regulation of DNA endoreduplication  identical protein binding  positive regulation of transcription from RNA polymerase II promoter  trophoblast giant cell differentiation  chorionic trophoblast cell differentiation  hepatocyte differentiation  negative regulation of transcription involved in G1/S transition of mitotic cell cycle  negative regulation of G1/S transition of mitotic cell cycle  
NDEx NetworkE2F7
Atlas of Cancer Signalling NetworkE2F7
Wikipedia pathwaysE2F7
Orthology - Evolution
OrthoDB144455
GeneTree (enSembl)ENSG00000165891
Phylogenetic Trees/Animal Genes : TreeFamE2F7
HOVERGENQ96AV8
HOGENOMQ96AV8
Homologs : HomoloGeneE2F7
Homology/Alignments : Family Browser (UCSC)E2F7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerE2F7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)E2F7
dbVarE2F7
ClinVarE2F7
1000_GenomesE2F7 
Exome Variant ServerE2F7
ExAC (Exome Aggregation Consortium)E2F7 (select the gene name)
Genetic variants : HAPMAP144455
Genomic Variants (DGV)E2F7 [DGVbeta]
DECIPHER (Syndromes)12:77415026-77459360  ENSG00000165891
CONAN: Copy Number AnalysisE2F7 
Mutations
ICGC Data PortalE2F7 
TCGA Data PortalE2F7 
Broad Tumor PortalE2F7
OASIS PortalE2F7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICE2F7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDE2F7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch E2F7
DgiDB (Drug Gene Interaction Database)E2F7
DoCM (Curated mutations)E2F7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)E2F7 (select a term)
intoGenE2F7
Cancer3DE2F7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612046   
Orphanet
MedgenE2F7
Genetic Testing Registry E2F7
NextProtQ96AV8 [Medical]
TSGene144455
GENETestsE2F7
Huge Navigator E2F7 [HugePedia]
snp3D : Map Gene to Disease144455
BioCentury BCIQE2F7
ClinGenE2F7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD144455
Chemical/Pharm GKB GenePA134894421
Clinical trialE2F7
Miscellaneous
canSAR (ICR)E2F7 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineE2F7
EVEXE2F7
GoPubMedE2F7
iHOPE2F7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:04:08 CET 2017

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