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E4F1 (E4F transcription factor 1)

Identity

Alias_symbol (synonym)E4F
Other alias
HGNC (Hugo) E4F1
LocusID (NCBI) 1877
Atlas_Id 40389
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 2223488 and ends at 2235742 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RAB26 (16p13.3) / E4F1 (16p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)E4F1   3121
Cards
Entrez_Gene (NCBI)E4F1  1877  E4F transcription factor 1
AliasesE4F
GeneCards (Weizmann)E4F1
Ensembl hg19 (Hinxton)ENSG00000167967 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167967 [Gene_View]  chr16:2223488-2235742 [Contig_View]  E4F1 [Vega]
ICGC DataPortalENSG00000167967
TCGA cBioPortalE4F1
AceView (NCBI)E4F1
Genatlas (Paris)E4F1
WikiGenes1877
SOURCE (Princeton)E4F1
Genetics Home Reference (NIH)E4F1
Genomic and cartography
GoldenPath hg38 (UCSC)E4F1  -     chr16:2223488-2235742 +  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)E4F1  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblE4F1 - 16p13.3 [CytoView hg19]  E4F1 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIE4F1 [Mapview hg19]  E4F1 [Mapview hg38]
OMIM603022   
Gene and transcription
Genbank (Entrez)AB209008 AK225132 AK290329 AK296784 BC014068
RefSeq transcript (Entrez)NM_001288776 NM_001288778 NM_004424
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)E4F1
Cluster EST : UnigeneHs.513268 [ NCBI ]
CGAP (NCI)Hs.513268
Alternative Splicing GalleryENSG00000167967
Gene ExpressionE4F1 [ NCBI-GEO ]   E4F1 [ EBI - ARRAY_EXPRESS ]   E4F1 [ SEEK ]   E4F1 [ MEM ]
Gene Expression Viewer (FireBrowse)E4F1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1877
GTEX Portal (Tissue expression)E4F1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ66K89   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ66K89  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ66K89
Splice isoforms : SwissVarQ66K89
PhosPhoSitePlusQ66K89
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam13912   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)E4F1
DMDM Disease mutations1877
Blocks (Seattle)E4F1
SuperfamilyQ66K89
Human Protein AtlasENSG00000167967
Peptide AtlasQ66K89
HPRD04317
IPIIPI00184135   IPI00556439   IPI00719649   
Protein Interaction databases
DIP (DOE-UCLA)Q66K89
IntAct (EBI)Q66K89
FunCoupENSG00000167967
BioGRIDE4F1
STRING (EMBL)E4F1
ZODIACE4F1
Ontologies - Pathways
QuickGOQ66K89
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  transcription corepressor activity  protein binding  nucleoplasm  cytoplasm  spindle  DNA replication  transcription, DNA-templated  cell proliferation  regulation of mitotic cell cycle, embryonic  regulation of cell cycle process  viral process  protein ubiquitination  transferase activity  cAMP response element binding  regulation of growth  metal ion binding  cell division  mitotic cell cycle arrest  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  transcription corepressor activity  protein binding  nucleoplasm  cytoplasm  spindle  DNA replication  transcription, DNA-templated  cell proliferation  regulation of mitotic cell cycle, embryonic  regulation of cell cycle process  viral process  protein ubiquitination  transferase activity  cAMP response element binding  regulation of growth  metal ion binding  cell division  mitotic cell cycle arrest  
NDEx NetworkE4F1
Atlas of Cancer Signalling NetworkE4F1
Wikipedia pathwaysE4F1
Orthology - Evolution
OrthoDB1877
GeneTree (enSembl)ENSG00000167967
Phylogenetic Trees/Animal Genes : TreeFamE4F1
HOVERGENQ66K89
HOGENOMQ66K89
Homologs : HomoloGeneE4F1
Homology/Alignments : Family Browser (UCSC)E4F1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerE4F1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)E4F1
dbVarE4F1
ClinVarE4F1
1000_GenomesE4F1 
Exome Variant ServerE4F1
ExAC (Exome Aggregation Consortium)E4F1 (select the gene name)
Genetic variants : HAPMAP1877
Genomic Variants (DGV)E4F1 [DGVbeta]
DECIPHERE4F1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisE4F1 
Mutations
ICGC Data PortalE4F1 
TCGA Data PortalE4F1 
Broad Tumor PortalE4F1
OASIS PortalE4F1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICE4F1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDE4F1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch E4F1
DgiDB (Drug Gene Interaction Database)E4F1
DoCM (Curated mutations)E4F1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)E4F1 (select a term)
intoGenE4F1
Cancer3DE4F1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603022   
Orphanet
MedgenE4F1
Genetic Testing Registry E4F1
NextProtQ66K89 [Medical]
TSGene1877
GENETestsE4F1
Target ValidationE4F1
Huge Navigator E4F1 [HugePedia]
snp3D : Map Gene to Disease1877
BioCentury BCIQE4F1
ClinGenE4F1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1877
Chemical/Pharm GKB GenePA27579
Clinical trialE4F1
Miscellaneous
canSAR (ICR)E4F1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineE4F1
EVEXE4F1
GoPubMedE4F1
iHOPE4F1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:32:01 CEST 2017

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