Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EAF1 (ELL associated factor 1)

Identity

Other alias-
HGNC (Hugo) EAF1
LocusID (NCBI) 85403
Atlas_Id 62702
Location 3p25.1  [Link to chromosome band 3p25]
Location_base_pair Starts at 15427557 and ends at 15442613 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GNAS (20q13.32) / EAF1 (3p25.1)KMT2A (11q23.3) / EAF1 (3p25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EAF1   20907
Cards
Entrez_Gene (NCBI)EAF1  85403  ELL associated factor 1
Aliases
GeneCards (Weizmann)EAF1
Ensembl hg19 (Hinxton)ENSG00000144597 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144597 [Gene_View]  chr3:15427557-15442613 [Contig_View]  EAF1 [Vega]
ICGC DataPortalENSG00000144597
TCGA cBioPortalEAF1
AceView (NCBI)EAF1
Genatlas (Paris)EAF1
WikiGenes85403
SOURCE (Princeton)EAF1
Genetics Home Reference (NIH)EAF1
Genomic and cartography
GoldenPath hg38 (UCSC)EAF1  -     chr3:15427557-15442613 +  3p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EAF1  -     3p25.1   [Description]    (hg19-Feb_2009)
EnsemblEAF1 - 3p25.1 [CytoView hg19]  EAF1 - 3p25.1 [CytoView hg38]
Mapping of homologs : NCBIEAF1 [Mapview hg19]  EAF1 [Mapview hg38]
OMIM608315   
Gene and transcription
Genbank (Entrez)AA626023 AF272973 AK023217 AK304697 AK312330
RefSeq transcript (Entrez)NM_033083
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EAF1
Cluster EST : UnigeneHs.716733 [ NCBI ]
CGAP (NCI)Hs.716733
Alternative Splicing GalleryENSG00000144597
Gene ExpressionEAF1 [ NCBI-GEO ]   EAF1 [ EBI - ARRAY_EXPRESS ]   EAF1 [ SEEK ]   EAF1 [ MEM ]
Gene Expression Viewer (FireBrowse)EAF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85403
GTEX Portal (Tissue expression)EAF1
Human Protein AtlasENSG00000144597-EAF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96JC9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96JC9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96JC9
Splice isoforms : SwissVarQ96JC9
PhosPhoSitePlusQ96JC9
Domains : Interpro (EBI)EAF_fam    Tscrpt_elong_fac_Eaf_N   
Domain families : Pfam (Sanger)EAF (PF09816)   
Domain families : Pfam (NCBI)pfam09816   
Conserved Domain (NCBI)EAF1
DMDM Disease mutations85403
Blocks (Seattle)EAF1
SuperfamilyQ96JC9
Human Protein Atlas [tissue]ENSG00000144597-EAF1 [tissue]
Peptide AtlasQ96JC9
HPRD12209
IPIIPI00878931   IPI00910326   IPI00797467   
Protein Interaction databases
DIP (DOE-UCLA)Q96JC9
IntAct (EBI)Q96JC9
FunCoupENSG00000144597
BioGRIDEAF1
STRING (EMBL)EAF1
ZODIACEAF1
Ontologies - Pathways
QuickGOQ96JC9
Ontology : AmiGOprotein binding  nucleoplasm  nucleoplasm  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  transcription elongation factor complex  Cajal body  nuclear body  nuclear speck  ELL-EAF complex  intracellular membrane-bounded organelle  intercellular bridge  
Ontology : EGO-EBIprotein binding  nucleoplasm  nucleoplasm  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  transcription elongation factor complex  Cajal body  nuclear body  nuclear speck  ELL-EAF complex  intracellular membrane-bounded organelle  intercellular bridge  
NDEx NetworkEAF1
Atlas of Cancer Signalling NetworkEAF1
Wikipedia pathwaysEAF1
Orthology - Evolution
OrthoDB85403
GeneTree (enSembl)ENSG00000144597
Phylogenetic Trees/Animal Genes : TreeFamEAF1
HOVERGENQ96JC9
HOGENOMQ96JC9
Homologs : HomoloGeneEAF1
Homology/Alignments : Family Browser (UCSC)EAF1
Gene fusions - Rearrangements
Fusion: Tumor Portal EAF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEAF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EAF1
dbVarEAF1
ClinVarEAF1
1000_GenomesEAF1 
Exome Variant ServerEAF1
ExAC (Exome Aggregation Consortium)ENSG00000144597
GNOMAD BrowserENSG00000144597
Genetic variants : HAPMAP85403
Genomic Variants (DGV)EAF1 [DGVbeta]
DECIPHEREAF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEAF1 
Mutations
ICGC Data PortalEAF1 
TCGA Data PortalEAF1 
Broad Tumor PortalEAF1
OASIS PortalEAF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEAF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEAF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EAF1
DgiDB (Drug Gene Interaction Database)EAF1
DoCM (Curated mutations)EAF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EAF1 (select a term)
intoGenEAF1
Cancer3DEAF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608315   
Orphanet
MedgenEAF1
Genetic Testing Registry EAF1
NextProtQ96JC9 [Medical]
TSGene85403
GENETestsEAF1
Target ValidationEAF1
Huge Navigator EAF1 [HugePedia]
snp3D : Map Gene to Disease85403
BioCentury BCIQEAF1
ClinGenEAF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85403
Chemical/Pharm GKB GenePA134897202
Clinical trialEAF1
Miscellaneous
canSAR (ICR)EAF1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEAF1
EVEXEAF1
GoPubMedEAF1
iHOPEAF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:45:20 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.