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EBF3 (EBF transcription factor 3)

Identity

Alias (NCBI)COE3
EBF-3
HADDS
O/E-2
OE-2
HGNC (Hugo) EBF3
HGNC Alias symbCOE3
DKFZp667B0210
HGNC Alias nameTranscription factor COE3
HGNC Previous nameearly B cell factor 3
LocusID (NCBI) 253738
Atlas_Id 49861
Location 10q26.3  [Link to chromosome band 10q26]
Location_base_pair Starts at 129835233 and ends at 129964274 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARL6IP5 (3p14.1) / EBF3 (10q26.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)EBF3   19087
Cards
Entrez_Gene (NCBI)EBF3    EBF transcription factor 3
AliasesCOE3; EBF-3; HADDS; O/E-2; 
OE-2
GeneCards (Weizmann)EBF3
Ensembl hg19 (Hinxton)ENSG00000108001 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108001 [Gene_View]  ENSG00000108001 [Sequence]  chr10:129835233-129964274 [Contig_View]  EBF3 [Vega]
ICGC DataPortalENSG00000108001
TCGA cBioPortalEBF3
AceView (NCBI)EBF3
Genatlas (Paris)EBF3
SOURCE (Princeton)EBF3
Genetics Home Reference (NIH)EBF3
Genomic and cartography
GoldenPath hg38 (UCSC)EBF3  -     chr10:129835233-129964274 -  10q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EBF3  -     10q26.3   [Description]    (hg19-Feb_2009)
GoldenPathEBF3 - 10q26.3 [CytoView hg19]  EBF3 - 10q26.3 [CytoView hg38]
ImmunoBaseENSG00000108001
Genome Data Viewer NCBIEBF3 [Mapview hg19]  
OMIM607407   617330   
Gene and transcription
Genbank (Entrez)AA330620 AK055710 AK097335 AK098025 AL713797
RefSeq transcript (Entrez)NM_001005463 NM_001375379 NM_001375380 NM_001375389 NM_001375390 NM_001375391 NM_001375392
Consensus coding sequences : CCDS (NCBI)EBF3
Gene ExpressionEBF3 [ NCBI-GEO ]   EBF3 [ EBI - ARRAY_EXPRESS ]   EBF3 [ SEEK ]   EBF3 [ MEM ]
Gene Expression Viewer (FireBrowse)EBF3 [ Firebrowse - Broad ]
GenevisibleExpression of EBF3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)253738
GTEX Portal (Tissue expression)EBF3
Human Protein AtlasENSG00000108001-EBF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4W6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4W6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4W6
PhosPhoSitePlusQ9H4W6
Domaine pattern : Prosite (Expaxy)COE (PS01345)   
Domains : Interpro (EBI)COE_DBD    COE_DBD_sf    COE_HLH    COE_IPT    HLH_DNA-bd_sf    Ig-like_fold    Ig_E-set    IPT_dom    Transcription_factor_COE    Transcription_factor_COE_CS   
Domain families : Pfam (Sanger)COE1_DBD (PF16422)    COE1_HLH (PF16423)    TIG (PF01833)   
Domain families : Pfam (NCBI)pfam16422    pfam16423    pfam01833   
Domain families : Smart (EMBL)IPT (SM00429)  
Conserved Domain (NCBI)EBF3
PDB (RSDB)3MUJ    3N50   
PDB Europe3MUJ    3N50   
PDB (PDBSum)3MUJ    3N50   
PDB (IMB)3MUJ    3N50   
Structural Biology KnowledgeBase3MUJ    3N50   
SCOP (Structural Classification of Proteins)3MUJ    3N50   
CATH (Classification of proteins structures)3MUJ    3N50   
SuperfamilyQ9H4W6
AlphaFold pdb e-kbQ9H4W6   
Human Protein Atlas [tissue]ENSG00000108001-EBF3 [tissue]
HPRD16818
Protein Interaction databases
DIP (DOE-UCLA)Q9H4W6
IntAct (EBI)Q9H4W6
BioGRIDEBF3
STRING (EMBL)EBF3
ZODIACEBF3
Ontologies - Pathways
QuickGOQ9H4W6
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  multicellular organism development  positive regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  multicellular organism development  positive regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkEBF3
Atlas of Cancer Signalling NetworkEBF3
Wikipedia pathwaysEBF3
Orthology - Evolution
OrthoDB253738
GeneTree (enSembl)ENSG00000108001
Phylogenetic Trees/Animal Genes : TreeFamEBF3
Homologs : HomoloGeneEBF3
Homology/Alignments : Family Browser (UCSC)EBF3
Gene fusions - Rearrangements
Fusion : QuiverEBF3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEBF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EBF3
dbVarEBF3
ClinVarEBF3
MonarchEBF3
1000_GenomesEBF3 
Exome Variant ServerEBF3
GNOMAD BrowserENSG00000108001
Varsome BrowserEBF3
ACMGEBF3 variants
VarityQ9H4W6
Genomic Variants (DGV)EBF3 [DGVbeta]
DECIPHEREBF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEBF3 
Mutations
ICGC Data PortalEBF3 
TCGA Data PortalEBF3 
Broad Tumor PortalEBF3
OASIS PortalEBF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEBF3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEBF3
Mutations and Diseases : HGMDEBF3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaEBF3
DgiDB (Drug Gene Interaction Database)EBF3
DoCM (Curated mutations)EBF3
CIViC (Clinical Interpretations of Variants in Cancer)EBF3
Cancer3DEBF3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607407    617330   
Orphanet
DisGeNETEBF3
MedgenEBF3
Genetic Testing Registry EBF3
NextProtQ9H4W6 [Medical]
GENETestsEBF3
Target ValidationEBF3
Huge Navigator EBF3 [HugePedia]
ClinGenEBF3
Clinical trials, drugs, therapy
MyCancerGenomeEBF3
Protein Interactions : CTDEBF3
Pharm GKB GenePA134972607
PharosQ9H4W6
Clinical trialEBF3
Miscellaneous
canSAR (ICR)EBF3
HarmonizomeEBF3
DataMed IndexEBF3
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXEBF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:07:37 CEST 2021
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