Atlas of Genetics and Cytogenetics in Oncology and Haematology

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EBF3 (EBF transcription factor 3)

Identity

Alias_symbol (synonym)COE3
DKFZp667B0210
Other aliasEBF-3
HADDS
O/E-2
OE-2
HGNC (Hugo) EBF3
LocusID (NCBI) 253738
Atlas_Id 49861
Location 10q26.3  [Link to chromosome band 10q26]
Location_base_pair Starts at 129835232 and ends at 129963827 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARL6IP5 (3p14.1) / EBF3 (10q26.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)EBF3   19087
Cards
Entrez_Gene (NCBI)EBF3  253738  EBF transcription factor 3
AliasesCOE3; EBF-3; HADDS; O/E-2; 
OE-2
GeneCards (Weizmann)EBF3
Ensembl hg19 (Hinxton)ENSG00000108001 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108001 [Gene_View]  ENSG00000108001 [Sequence]  chr10:129835232-129963827 [Contig_View]  EBF3 [Vega]
ICGC DataPortalENSG00000108001
TCGA cBioPortalEBF3
AceView (NCBI)EBF3
Genatlas (Paris)EBF3
WikiGenes253738
SOURCE (Princeton)EBF3
Genetics Home Reference (NIH)EBF3
Genomic and cartography
GoldenPath hg38 (UCSC)EBF3  -     chr10:129835232-129963827 -  10q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EBF3  -     10q26.3   [Description]    (hg19-Feb_2009)
EnsemblEBF3 - 10q26.3 [CytoView hg19]  EBF3 - 10q26.3 [CytoView hg38]
Mapping of homologs : NCBIEBF3 [Mapview hg19]  EBF3 [Mapview hg38]
OMIM607407   617330   
Gene and transcription
Genbank (Entrez)AA330620 AK055710 AK097335 AK098025 AL713797
RefSeq transcript (Entrez)NM_001005463
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EBF3
Cluster EST : UnigeneHs.591374 [ NCBI ]
CGAP (NCI)Hs.591374
Alternative Splicing GalleryENSG00000108001
Gene ExpressionEBF3 [ NCBI-GEO ]   EBF3 [ EBI - ARRAY_EXPRESS ]   EBF3 [ SEEK ]   EBF3 [ MEM ]
Gene Expression Viewer (FireBrowse)EBF3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)253738
GTEX Portal (Tissue expression)EBF3
Human Protein AtlasENSG00000108001-EBF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4W6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4W6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4W6
Splice isoforms : SwissVarQ9H4W6
PhosPhoSitePlusQ9H4W6
Domaine pattern : Prosite (Expaxy)COE (PS01345)   
Domains : Interpro (EBI)COE_DBD    COE_DBD_sf    COE_HLH    COE_IPT    HLH_DNA-bd_sf    Ig-like_fold    Ig_E-set    IPT_dom    Transcription_factor_COE    Transcription_factor_COE_CS   
Domain families : Pfam (Sanger)COE1_DBD (PF16422)    COE1_HLH (PF16423)    TIG (PF01833)   
Domain families : Pfam (NCBI)pfam16422    pfam16423    pfam01833   
Domain families : Smart (EMBL)IPT (SM00429)  
Conserved Domain (NCBI)EBF3
DMDM Disease mutations253738
Blocks (Seattle)EBF3
PDB (SRS)3MUJ    3N50   
PDB (PDBSum)3MUJ    3N50   
PDB (IMB)3MUJ    3N50   
PDB (RSDB)3MUJ    3N50   
Structural Biology KnowledgeBase3MUJ    3N50   
SCOP (Structural Classification of Proteins)3MUJ    3N50   
CATH (Classification of proteins structures)3MUJ    3N50   
SuperfamilyQ9H4W6
Human Protein Atlas [tissue]ENSG00000108001-EBF3 [tissue]
Peptide AtlasQ9H4W6
HPRD16818
IPIIPI00024242   IPI00220430   IPI00514247   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4W6
IntAct (EBI)Q9H4W6
FunCoupENSG00000108001
BioGRIDEBF3
STRING (EMBL)EBF3
ZODIACEBF3
Ontologies - Pathways
QuickGOQ9H4W6
Ontology : AmiGORNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  nucleus  nucleus  multicellular organism development  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  metal ion binding  protein dimerization activity  
Ontology : EGO-EBIRNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  nucleus  nucleus  multicellular organism development  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  metal ion binding  protein dimerization activity  
NDEx NetworkEBF3
Atlas of Cancer Signalling NetworkEBF3
Wikipedia pathwaysEBF3
Orthology - Evolution
OrthoDB253738
GeneTree (enSembl)ENSG00000108001
Phylogenetic Trees/Animal Genes : TreeFamEBF3
HOVERGENQ9H4W6
HOGENOMQ9H4W6
Homologs : HomoloGeneEBF3
Homology/Alignments : Family Browser (UCSC)EBF3
Gene fusions - Rearrangements
Fusion : QuiverEBF3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEBF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EBF3
dbVarEBF3
ClinVarEBF3
1000_GenomesEBF3 
Exome Variant ServerEBF3
ExAC (Exome Aggregation Consortium)ENSG00000108001
GNOMAD BrowserENSG00000108001
Varsome BrowserEBF3
Genetic variants : HAPMAP253738
Genomic Variants (DGV)EBF3 [DGVbeta]
DECIPHEREBF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEBF3 
Mutations
ICGC Data PortalEBF3 
TCGA Data PortalEBF3 
Broad Tumor PortalEBF3
OASIS PortalEBF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEBF3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEBF3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EBF3
DgiDB (Drug Gene Interaction Database)EBF3
DoCM (Curated mutations)EBF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EBF3 (select a term)
intoGenEBF3
Cancer3DEBF3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607407    617330   
Orphanet
DisGeNETEBF3
MedgenEBF3
Genetic Testing Registry EBF3
NextProtQ9H4W6 [Medical]
TSGene253738
GENETestsEBF3
Target ValidationEBF3
Huge Navigator EBF3 [HugePedia]
snp3D : Map Gene to Disease253738
BioCentury BCIQEBF3
ClinGenEBF3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD253738
Chemical/Pharm GKB GenePA134972607
Clinical trialEBF3
Miscellaneous
canSAR (ICR)EBF3 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEBF3
EVEXEBF3
GoPubMedEBF3
iHOPEBF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Nov 6 11:03:45 CET 2018
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