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EDARADD (EDAR associated death domain)

Identity

Alias (NCBI)ECTD11A
ECTD11B
ED3
EDA3
HGNC (Hugo) EDARADD
LocusID (NCBI) 128178
Atlas_Id 55435
Location 1q42.3  [Link to chromosome band 1q42]
Location_base_pair Starts at 236394286 and ends at 236484930 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EDARADD (1q42.3) / OSMR (5p13.1)LGALS8 (1q43) / EDARADD (1q42.3)SMYD3 (1q44) / EDARADD (1q42.3)
TGFBR3 (1p22.1) / EDARADD (1q42.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)EDARADD   14341
Cards
Entrez_Gene (NCBI)EDARADD    EDAR associated death domain
AliasesECTD11A; ECTD11B; ED3; EDA3
GeneCards (Weizmann)EDARADD
Ensembl hg19 (Hinxton)ENSG00000186197 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186197 [Gene_View]  ENSG00000186197 [Sequence]  chr1:236394286-236484930 [Contig_View]  EDARADD [Vega]
ICGC DataPortalENSG00000186197
TCGA cBioPortalEDARADD
AceView (NCBI)EDARADD
Genatlas (Paris)EDARADD
SOURCE (Princeton)EDARADD
Genetics Home Reference (NIH)EDARADD
Genomic and cartography
GoldenPath hg38 (UCSC)EDARADD  -     chr1:236394286-236484930 +  1q42.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EDARADD  -     1q42.3   [Description]    (hg19-Feb_2009)
GoldenPathEDARADD - 1q42.3 [CytoView hg19]  EDARADD - 1q42.3 [CytoView hg38]
ImmunoBaseENSG00000186197
Genome Data Viewer NCBIEDARADD [Mapview hg19]  
OMIM129490   224900   606603   614940   614941   
Gene and transcription
Genbank (Entrez)AK096339 AK290862 AK291930 AK314634 AY028913
RefSeq transcript (Entrez)NM_080738 NM_145861
Consensus coding sequences : CCDS (NCBI)EDARADD
Gene ExpressionEDARADD [ NCBI-GEO ]   EDARADD [ EBI - ARRAY_EXPRESS ]   EDARADD [ SEEK ]   EDARADD [ MEM ]
Gene Expression Viewer (FireBrowse)EDARADD [ Firebrowse - Broad ]
GenevisibleExpression of EDARADD in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)128178
GTEX Portal (Tissue expression)EDARADD
Human Protein AtlasENSG00000186197-EDARADD [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WWZ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WWZ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WWZ3
PhosPhoSitePlusQ8WWZ3
Domains : Interpro (EBI)DEATH-like_dom_sf    Death_domain    EDARADD   
Domain families : Pfam (Sanger)Death (PF00531)   
Domain families : Pfam (NCBI)pfam00531   
Conserved Domain (NCBI)EDARADD
SuperfamilyQ8WWZ3
AlphaFold pdb e-kbQ8WWZ3   
Human Protein Atlas [tissue]ENSG00000186197-EDARADD [tissue]
HPRD05965
Protein Interaction databases
DIP (DOE-UCLA)Q8WWZ3
IntAct (EBI)Q8WWZ3
BioGRIDEDARADD
STRING (EMBL)EDARADD
ZODIACEDARADD
Ontologies - Pathways
QuickGOQ8WWZ3
Ontology : AmiGOprotein binding  cytosol  multicellular organism development  cell differentiation  tumor necrosis factor-mediated signaling pathway  positive regulation of NIK/NF-kappaB signaling  
Ontology : EGO-EBIprotein binding  cytosol  multicellular organism development  cell differentiation  tumor necrosis factor-mediated signaling pathway  positive regulation of NIK/NF-kappaB signaling  
NDEx NetworkEDARADD
Atlas of Cancer Signalling NetworkEDARADD
Wikipedia pathwaysEDARADD
Orthology - Evolution
OrthoDB128178
GeneTree (enSembl)ENSG00000186197
Phylogenetic Trees/Animal Genes : TreeFamEDARADD
Homologs : HomoloGeneEDARADD
Homology/Alignments : Family Browser (UCSC)EDARADD
Gene fusions - Rearrangements
Fusion : QuiverEDARADD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEDARADD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EDARADD
dbVarEDARADD
ClinVarEDARADD
MonarchEDARADD
1000_GenomesEDARADD 
Exome Variant ServerEDARADD
GNOMAD BrowserENSG00000186197
Varsome BrowserEDARADD
ACMGEDARADD variants
VarityQ8WWZ3
Genomic Variants (DGV)EDARADD [DGVbeta]
DECIPHEREDARADD [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEDARADD 
Mutations
ICGC Data PortalEDARADD 
TCGA Data PortalEDARADD 
Broad Tumor PortalEDARADD
OASIS PortalEDARADD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEDARADD  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEDARADD
Mutations and Diseases : HGMDEDARADD
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaEDARADD
DgiDB (Drug Gene Interaction Database)EDARADD
DoCM (Curated mutations)EDARADD
CIViC (Clinical Interpretations of Variants in Cancer)EDARADD
Cancer3DEDARADD
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM129490    224900    606603    614940    614941   
Orphanet7026    7027    14371   
DisGeNETEDARADD
MedgenEDARADD
Genetic Testing Registry EDARADD
NextProtQ8WWZ3 [Medical]
GENETestsEDARADD
Target ValidationEDARADD
Huge Navigator EDARADD [HugePedia]
ClinGenEDARADD
Clinical trials, drugs, therapy
MyCancerGenomeEDARADD
Protein Interactions : CTDEDARADD
Pharm GKB GenePA27603
PharosQ8WWZ3
Clinical trialEDARADD
Miscellaneous
canSAR (ICR)EDARADD
HarmonizomeEDARADD
DataMed IndexEDARADD
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXEDARADD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:07:41 CEST 2021

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