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EDC3 (enhancer of mRNA decapping 3)

Identity

Alias_namesYJDC
yjeF domain containing (E.coli)
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
Alias_symbol (synonym)FLJ21128
hYjeF_N2-15q23
YJEFN2
LSM16
Other aliasMRT50
HGNC (Hugo) EDC3
LocusID (NCBI) 80153
Atlas_Id 62723
Location 15q24.1  [Link to chromosome band 15q24]
Location_base_pair Starts at 74630558 and ends at 74696045 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EDC3 (15q24.1) / EDC3 (15q24.1)EDC3 (15q24.1) / SNX29 (16p13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EDC3   26114
Cards
Entrez_Gene (NCBI)EDC3  80153  enhancer of mRNA decapping 3
AliasesLSM16; MRT50; YJDC; YJEFN2
GeneCards (Weizmann)EDC3
Ensembl hg19 (Hinxton)ENSG00000179151 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179151 [Gene_View]  chr15:74630558-74696045 [Contig_View]  EDC3 [Vega]
ICGC DataPortalENSG00000179151
TCGA cBioPortalEDC3
AceView (NCBI)EDC3
Genatlas (Paris)EDC3
WikiGenes80153
SOURCE (Princeton)EDC3
Genetics Home Reference (NIH)EDC3
Genomic and cartography
GoldenPath hg38 (UCSC)EDC3  -     chr15:74630558-74696045 -  15q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EDC3  -     15q24.1   [Description]    (hg19-Feb_2009)
EnsemblEDC3 - 15q24.1 [CytoView hg19]  EDC3 - 15q24.1 [CytoView hg38]
Mapping of homologs : NCBIEDC3 [Mapview hg19]  EDC3 [Mapview hg38]
OMIM609842   616460   
Gene and transcription
Genbank (Entrez)AF193058 AK024781 AK056339 AK225099 AL133447
RefSeq transcript (Entrez)NM_001142443 NM_001142444 NM_025083
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EDC3
Cluster EST : UnigeneHs.682454 [ NCBI ]
CGAP (NCI)Hs.682454
Alternative Splicing GalleryENSG00000179151
Gene ExpressionEDC3 [ NCBI-GEO ]   EDC3 [ EBI - ARRAY_EXPRESS ]   EDC3 [ SEEK ]   EDC3 [ MEM ]
Gene Expression Viewer (FireBrowse)EDC3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80153
GTEX Portal (Tissue expression)EDC3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96F86   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96F86  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96F86
Splice isoforms : SwissVarQ96F86
PhosPhoSitePlusQ96F86
Domaine pattern : Prosite (Expaxy)DFDF (PS51512)    YJEF_N (PS51385)   
Domains : Interpro (EBI)DFDF    FDF_dom    Lsm14-like_N    Lsm16_N    YjeF_N_dom   
Domain families : Pfam (Sanger)FDF (PF09532)    LSM14 (PF12701)    YjeF_N (PF03853)   
Domain families : Pfam (NCBI)pfam09532    pfam12701    pfam03853   
Domain families : Smart (EMBL)FDF (SM01199)  LSM14 (SM01271)  
Conserved Domain (NCBI)EDC3
DMDM Disease mutations80153
Blocks (Seattle)EDC3
PDB (SRS)2VC8    2WAX    2WAY    3D3J    3D3K   
PDB (PDBSum)2VC8    2WAX    2WAY    3D3J    3D3K   
PDB (IMB)2VC8    2WAX    2WAY    3D3J    3D3K   
PDB (RSDB)2VC8    2WAX    2WAY    3D3J    3D3K   
Structural Biology KnowledgeBase2VC8    2WAX    2WAY    3D3J    3D3K   
SCOP (Structural Classification of Proteins)2VC8    2WAX    2WAY    3D3J    3D3K   
CATH (Classification of proteins structures)2VC8    2WAX    2WAY    3D3J    3D3K   
SuperfamilyQ96F86
Human Protein AtlasENSG00000179151
Peptide AtlasQ96F86
HPRD07954
IPIIPI00018009   
Protein Interaction databases
DIP (DOE-UCLA)Q96F86
IntAct (EBI)Q96F86
FunCoupENSG00000179151
BioGRIDEDC3
STRING (EMBL)EDC3
ZODIACEDC3
Ontologies - Pathways
QuickGOQ96F86
Ontology : AmiGOP-body  P-body  mRNA binding  protein binding  cytosol  membrane  deadenylation-independent decapping of nuclear-transcribed mRNA  cytoplasmic mRNA processing body assembly  identical protein binding  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  RNA phosphodiester bond hydrolysis, endonucleolytic  phosphodiesterase decapping endonuclease activity  
Ontology : EGO-EBIP-body  P-body  mRNA binding  protein binding  cytosol  membrane  deadenylation-independent decapping of nuclear-transcribed mRNA  cytoplasmic mRNA processing body assembly  identical protein binding  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  RNA phosphodiester bond hydrolysis, endonucleolytic  phosphodiesterase decapping endonuclease activity  
Pathways : KEGGRNA degradation   
NDEx NetworkEDC3
Atlas of Cancer Signalling NetworkEDC3
Wikipedia pathwaysEDC3
Orthology - Evolution
OrthoDB80153
GeneTree (enSembl)ENSG00000179151
Phylogenetic Trees/Animal Genes : TreeFamEDC3
HOVERGENQ96F86
HOGENOMQ96F86
Homologs : HomoloGeneEDC3
Homology/Alignments : Family Browser (UCSC)EDC3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEDC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EDC3
dbVarEDC3
ClinVarEDC3
1000_GenomesEDC3 
Exome Variant ServerEDC3
ExAC (Exome Aggregation Consortium)EDC3 (select the gene name)
Genetic variants : HAPMAP80153
Genomic Variants (DGV)EDC3 [DGVbeta]
DECIPHEREDC3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEDC3 
Mutations
ICGC Data PortalEDC3 
TCGA Data PortalEDC3 
Broad Tumor PortalEDC3
OASIS PortalEDC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEDC3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEDC3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EDC3
DgiDB (Drug Gene Interaction Database)EDC3
DoCM (Curated mutations)EDC3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EDC3 (select a term)
intoGenEDC3
Cancer3DEDC3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609842    616460   
Orphanet11804   
MedgenEDC3
Genetic Testing Registry EDC3
NextProtQ96F86 [Medical]
TSGene80153
GENETestsEDC3
Target ValidationEDC3
Huge Navigator EDC3 [HugePedia]
snp3D : Map Gene to Disease80153
BioCentury BCIQEDC3
ClinGenEDC3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80153
Chemical/Pharm GKB GenePA142670551
Clinical trialEDC3
Miscellaneous
canSAR (ICR)EDC3 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEDC3
EVEXEDC3
GoPubMedEDC3
iHOPEDC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:06:50 CEST 2017

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