EDEM1 (ER degradation enhancer, mannosidase alpha-like 1)

Identity

Other names	EDEM
	KIAA0212
HGNC	EDEM1
Location	3p26.1
Location_base_pair	Starts at 5204433 and ends at 5236642 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	EDEM1   18967
Entrez_Gene	EDEM1  9695  ER degradation enhancer, mannosidase alpha-like 1
	Cards
GeneCards	EDEM1
Ensembl	EDEM1 [Search_View]   ENSG00000134109 [Gene_View]
Genatlas	EDEM1
GeneLynx	EDEM1
eGenome	EDEM1
euGene	9695
	Genomic and cartography
GoldenPath	EDEM1  -  3p26.1   chr3:5204433-5236642 +  3p26.2   [Description]    (hg18-March_2006)
Ensembl	EDEM1 - 3p26.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	EDEM1
	Gene and transcription
Genbank	AK292643 [ ENTREZ ]
Genbank	BC019088 [ ENTREZ ]
Genbank	CR597249 [ ENTREZ ]
Genbank	CR621147 [ ENTREZ ]
Genbank	D86967 [ ENTREZ ]
RefSeq	NM_014674 [ SRS ]    NM_014674 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	AC_000135 [ SRS ]    AC_000135 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022517 [ SRS ]    NT_022517 [ ENTREZ ]
RefSeq	NW_001838876 [ SRS ]    NW_001838876 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
AceView	EDEM1 AceView - NCBI
Unigene	Hs.224616 [ SRS ]    Hs.224616 [ NCBI ]     HS224616 [ spliceNest ]
Fast-db	995 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q92611 [ SRS]    Q92611 [ EXPASY ]     Q92611 [ INTERPRO ]     Q92611 [ UNIPROT ]
Interpro	IPR001382 Glyco_hydro_47 [ SRS ]    IPR001382 Glyco_hydro_47 [ EBI ]
CluSTr	Q92611
Pfam	PF01532 Glyco_hydro_47 [ SRS ]    PF01532 Glyco_hydro_47 [ Sanger ]    pfam01532 [ NCBI-CDD ]
Blocks	Q92611
HPRD	09644
	Protein Interaction databases
DIP	Q92611
IntAct	Q92611
	Polymorphism : SNP, mutations, diseases
OMIM	607673    [ map ]
GENECLINICS	607673
SNP	EDEM1 [dbSNP-NCBI]
SNP	NM_014674 [SNP-NCI]
SNP	EDEM1 [GeneSNPs - Utah]  EDEM1] [HGBASE - SRS]
HAPMAP	EDEM1 [HAPMAP]
HGMD	EDEM1
	General knowledge
Family Browser	EDEM1 [UCSC Family Browser]
SOURCE	NM_014674
SMD	Hs.224616
SAGE	Hs.224616
GO	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [Amigo]  mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	protein binding [Amigo]  protein binding
GO	endoplasmic reticulum [Amigo]  endoplasmic reticulum
GO	endoplasmic reticulum membrane [Amigo]  endoplasmic reticulum membrane
GO	response to unfolded protein [Amigo]  response to unfolded protein
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	integral to endoplasmic reticulum membrane [Amigo]  integral to endoplasmic reticulum membrane
GO	ER-associated protein catabolic process [Amigo]  ER-associated protein catabolic process
BIOCARTA	ERöassociated degradation (ERAD) Pathway    [Genes]
KEGG	Nucleotide sugars metabolism
KEGG	Aminosugars metabolism
PubGene	EDEM1
TreeFam	EDEM1
CTD	9695 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	EDEM1 Related clones (RZPD - Berlin)
	PubMed
PubMed	12 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:39:24 2008