Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9695
MIM: 607673
HGNC: 18967
Ensembl: ENSG00000134109
Variants:
dbSNP: 9695
ClinVar: 9695
TCGA: ENSG00000134109
COSMIC: EDEM1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34698634 | 2021 | Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD. | 7 |
| 35008544 | 2021 | EDEM1 Regulates Amyloid Precursor Protein (APP) Metabolism and Amyloid-β Production. | 4 |
| 34698634 | 2021 | Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD. | 7 |
| 35008544 | 2021 | EDEM1 Regulates Amyloid Precursor Protein (APP) Metabolism and Amyloid-β Production. | 4 |
| 32083795 | 2020 | Cleavage and degradation of EDEM1 promotes coxsackievirus B3 replication via ATF6a-mediated unfolded protein response signalling. | 1 |
| 32423001 | 2020 | EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired. | 17 |
| 32083795 | 2020 | Cleavage and degradation of EDEM1 promotes coxsackievirus B3 replication via ATF6a-mediated unfolded protein response signalling. | 1 |
| 32423001 | 2020 | EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired. | 17 |
| 30021839 | 2018 | EDEM1's mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity. | 22 |
| 30281916 | 2018 | Alterations of EDEM1 functions enhance ATF6 pro-survival signaling. | 22 |
| 30021839 | 2018 | EDEM1's mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity. | 22 |
| 30281916 | 2018 | Alterations of EDEM1 functions enhance ATF6 pro-survival signaling. | 22 |
| 24037343 | 2014 | Identification of genes promoting skin youthfulness by genome-wide association study. | 5 |
| 24664425 | 2014 | ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase. | 12 |
| 24913918 | 2014 | MicroRNA-581 promotes hepatitis B virus surface antigen expression by targeting Dicer and EDEM1. | 13 |
Citation
Dessen P
EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45857/edem1
