| Nomenclature |
HGNC (Hugo) | EDF1 3164 |
| Cards |
Entrez_Gene (NCBI) | EDF1 8721 endothelial differentiation related factor 1 |
Aliases | CFAP280; EDF-1; MBF1 |
GeneCards (Weizmann) | EDF1 |
Ensembl hg19 (Hinxton) | ENSG00000107223 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000107223 [Gene_View] chr9:136862669-136866336 [Contig_View] EDF1 [Vega] |
ICGC DataPortal | ENSG00000107223 |
TCGA cBioPortal | EDF1 |
AceView (NCBI) | EDF1 |
Genatlas (Paris) | EDF1 |
WikiGenes | 8721 |
SOURCE (Princeton) | EDF1 |
Genetics Home Reference (NIH) | EDF1 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | EDF1 - chr9:136862669-136866336 - 9q34.3 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | EDF1 - 9q34.3 [Description] (hg19-Feb_2009) |
Ensembl | EDF1 - 9q34.3 [CytoView hg19] EDF1 - 9q34.3 [CytoView hg38] |
Mapping of homologs : NCBI | EDF1 [Mapview hg19] EDF1 [Mapview hg38] |
OMIM | 605107 |
| Gene and transcription |
Genbank (Entrez) | AA325420 AB002282 AB002283 BC015500 BI833652 |
RefSeq transcript (Entrez) | NM_001281297 NM_001281298 NM_001281299 NM_003792 NM_153200 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | EDF1 |
Cluster EST : Unigene | Hs.174050 [ NCBI ] |
CGAP (NCI) | Hs.174050 |
Alternative Splicing Gallery | ENSG00000107223 |
Gene Expression | EDF1 [ NCBI-GEO ] EDF1 [ EBI - ARRAY_EXPRESS ]
EDF1 [ SEEK ] EDF1 [ MEM ] |
Gene Expression Viewer (FireBrowse) | EDF1 [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 8721 |
GTEX Portal (Tissue expression) | EDF1 |
Human Protein Atlas | ENSG00000107223-EDF1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | O60869 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | O60869 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | O60869 |
Splice isoforms : SwissVar | O60869 |
PhosPhoSitePlus | O60869 |
Domaine pattern : Prosite (Expaxy) | HTH_CROC1 (PS50943) |
Domains : Interpro (EBI) | Cro/C1-type_HTH Lambda_DNA-bd_dom MBF1_N |
Domain families : Pfam (Sanger) | HTH_3 (PF01381) MBF1 (PF08523) |
Domain families : Pfam (NCBI) | pfam01381 pfam08523 |
Domain families : Smart (EMBL) | HTH_XRE (SM00530) |
Conserved Domain (NCBI) | EDF1 |
DMDM Disease mutations | 8721 |
Blocks (Seattle) | EDF1 |
PDB (SRS) | 1X57 |
PDB (PDBSum) | 1X57 |
PDB (IMB) | 1X57 |
PDB (RSDB) | 1X57 |
Structural Biology KnowledgeBase | 1X57 |
SCOP (Structural Classification of Proteins) | 1X57 |
CATH (Classification of proteins structures) | 1X57 |
Superfamily | O60869 |
Human Protein Atlas [tissue] | ENSG00000107223-EDF1 [tissue] |
Peptide Atlas | O60869 |
HPRD | 09235 |
IPI | IPI00021570 IPI00006362 IPI00640567 |
| Protein Interaction databases |
DIP (DOE-UCLA) | O60869 |
IntAct (EBI) | O60869 |
FunCoup | ENSG00000107223 |
BioGRID | EDF1 |
STRING (EMBL) | EDF1 |
ZODIAC | EDF1 |
| Ontologies - Pathways |
QuickGO | O60869 |
Ontology : AmiGO | DNA binding transcription factor activity transcription coactivator activity RNA binding histone acetyltransferase activity protein binding calmodulin binding intracellular nucleus nucleus transcription factor TFIID complex nucleolus cytoplasm cytosol transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development methyltransferase activity regulation of lipid metabolic process positive regulation of DNA binding sequence-specific DNA binding endothelial cell differentiation positive regulation of transcription, DNA-templated extracellular exosome |
Ontology : EGO-EBI | DNA binding transcription factor activity transcription coactivator activity RNA binding histone acetyltransferase activity protein binding calmodulin binding intracellular nucleus nucleus transcription factor TFIID complex nucleolus cytoplasm cytosol transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development methyltransferase activity regulation of lipid metabolic process positive regulation of DNA binding sequence-specific DNA binding endothelial cell differentiation positive regulation of transcription, DNA-templated extracellular exosome |
NDEx Network | EDF1 |
Atlas of Cancer Signalling Network | EDF1 |
Wikipedia pathways | EDF1 |
| Orthology - Evolution |
OrthoDB | 8721 |
GeneTree (enSembl) | ENSG00000107223 |
Phylogenetic Trees/Animal Genes : TreeFam | EDF1 |
HOVERGEN | O60869 |
HOGENOM | O60869 |
Homologs : HomoloGene | EDF1 |
Homology/Alignments : Family Browser (UCSC) | EDF1 |
| Gene fusions - Rearrangements |
Fusion : Quiver | EDF1 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | EDF1 [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | EDF1 |
dbVar | EDF1 |
ClinVar | EDF1 |
1000_Genomes | EDF1 |
Exome Variant Server | EDF1 |
ExAC (Exome Aggregation Consortium) | ENSG00000107223 |
GNOMAD Browser | ENSG00000107223 |
Genetic variants : HAPMAP | 8721 |
Genomic Variants (DGV) | EDF1 [DGVbeta] |
DECIPHER | EDF1 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | EDF1 |
| Mutations |
ICGC Data Portal | EDF1 |
TCGA Data Portal | EDF1 |
Broad Tumor Portal | EDF1 |
OASIS Portal | EDF1 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | EDF1 [overview] [genome browser] [tissue] [distribution] |
Mutations and Diseases : HGMD | EDF1 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search EDF1 |
DgiDB (Drug Gene Interaction Database) | EDF1 |
DoCM (Curated mutations) | EDF1 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | EDF1 (select a term) |
intoGen | EDF1 |
Cancer3D | EDF1(select the gene name) |
Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 605107 |
Orphanet | |
DisGeNET | EDF1 |
Medgen | EDF1 |
Genetic Testing Registry | EDF1
|
NextProt | O60869 [Medical] |
TSGene | 8721 |
GENETests | EDF1 |
Target Validation | EDF1 |
Huge Navigator |
EDF1 [HugePedia] |
snp3D : Map Gene to Disease | 8721 |
BioCentury BCIQ | EDF1 |
ClinGen | EDF1 |
| Clinical trials, drugs, therapy |
---|
Chemical/Protein Interactions : CTD | 8721 |
Chemical/Pharm GKB Gene | PA27604 |
Clinical trial | EDF1 |
| Miscellaneous |
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canSAR (ICR) | EDF1 (select the gene name) |
| Probes |
---|
| Litterature |
---|
PubMed | 30 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | EDF1 |
EVEX | EDF1 |
GoPubMed | EDF1 |
iHOP | EDF1 |