| Nomenclature |
|---|
| HGNC (Hugo) | EDF1 3164 |
| Cards |
|---|
| Entrez_Gene (NCBI) | EDF1 8721 endothelial differentiation related factor 1 |
| Aliases | CFAP280; EDF-1; MBF1 |
| GeneCards (Weizmann) | EDF1 |
| Ensembl hg19 (Hinxton) | ENSG00000107223 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000107223 [Gene_View] chr9:136862114-136866336 [Contig_View] EDF1 [Vega] |
| ICGC DataPortal | ENSG00000107223 |
| TCGA cBioPortal | EDF1 |
| AceView (NCBI) | EDF1 |
| Genatlas (Paris) | EDF1 |
| WikiGenes | 8721 |
| SOURCE (Princeton) | EDF1 |
| Genetics Home Reference (NIH) | EDF1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | EDF1 - chr9:136862114-136866336 - 9q34.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | EDF1 - 9q34.3 [Description] (hg19-Feb_2009) |
| Ensembl | EDF1 - 9q34.3 [CytoView hg19] EDF1 - 9q34.3 [CytoView hg38] |
| Mapping of homologs : NCBI | EDF1 [Mapview hg19] EDF1 [Mapview hg38] |
| OMIM | 605107 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AA325420 AB002282 AB002283 BC015500 BI833652 |
| RefSeq transcript (Entrez) | NM_001281297 NM_001281298 NM_001281299 NM_003792 NM_153200 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | EDF1 |
| Cluster EST : Unigene | Hs.174050 [ NCBI ] |
| CGAP (NCI) | Hs.174050 |
| Alternative Splicing Gallery | ENSG00000107223 |
| Gene Expression | EDF1 [ NCBI-GEO ] EDF1 [ EBI - ARRAY_EXPRESS ]
EDF1 [ SEEK ] EDF1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | EDF1 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevisible | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 8721 |
| GTEX Portal (Tissue expression) | EDF1 |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O60869 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O60869 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O60869 |
| Splice isoforms : SwissVar | O60869 |
| PhosPhoSitePlus | O60869 |
| Domaine pattern : Prosite (Expaxy) | HTH_CROC1 (PS50943) |
| Domains : Interpro (EBI) | Cro/C1-type_HTH Lambda_DNA-bd_dom MBF1_N |
| Domain families : Pfam (Sanger) | HTH_3 (PF01381) MBF1 (PF08523) |
| Domain families : Pfam (NCBI) | pfam01381 pfam08523 |
| Domain families : Smart (EMBL) | HTH_XRE (SM00530) |
| Conserved Domain (NCBI) | EDF1 |
| DMDM Disease mutations | 8721 |
| Blocks (Seattle) | EDF1 |
| PDB (SRS) | 1X57 |
| PDB (PDBSum) | 1X57 |
| PDB (IMB) | 1X57 |
| PDB (RSDB) | 1X57 |
| Structural Biology KnowledgeBase | 1X57 |
| SCOP (Structural Classification of Proteins) | 1X57 |
| CATH (Classification of proteins structures) | 1X57 |
| Superfamily | O60869 |
| Human Protein Atlas | ENSG00000107223 |
| Peptide Atlas | O60869 |
| HPRD | 09235 |
| IPI | IPI00021570 IPI00006362 IPI00640567 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O60869 |
| IntAct (EBI) | O60869 |
| FunCoup | ENSG00000107223 |
| BioGRID | EDF1 |
| STRING (EMBL) | EDF1 |
| ZODIAC | EDF1 |
| Ontologies - Pathways |
|---|
| QuickGO | O60869 |
| Ontology : AmiGO | transcription factor activity, sequence-specific DNA binding transcription coactivator activity RNA binding histone acetyltransferase activity protein binding calmodulin binding intracellular nucleus nucleus transcription factor TFIID complex nucleolus cytoplasm cytosol transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development methyltransferase activity regulation of lipid metabolic process positive regulation of DNA binding sequence-specific DNA binding endothelial cell differentiation positive regulation of transcription, DNA-templated extracellular exosome |
| Ontology : EGO-EBI | transcription factor activity, sequence-specific DNA binding transcription coactivator activity RNA binding histone acetyltransferase activity protein binding calmodulin binding intracellular nucleus nucleus transcription factor TFIID complex nucleolus cytoplasm cytosol transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development methyltransferase activity regulation of lipid metabolic process positive regulation of DNA binding sequence-specific DNA binding endothelial cell differentiation positive regulation of transcription, DNA-templated extracellular exosome |
| NDEx Network | EDF1 |
| Atlas of Cancer Signalling Network | EDF1 |
| Wikipedia pathways | EDF1 |
| Orthology - Evolution |
|---|
| OrthoDB | 8721 |
| GeneTree (enSembl) | ENSG00000107223 |
| Phylogenetic Trees/Animal Genes : TreeFam | EDF1 |
| HOVERGEN | O60869 |
| HOGENOM | O60869 |
| Homologs : HomoloGene | EDF1 |
| Homology/Alignments : Family Browser (UCSC) | EDF1 |
| Gene fusions - Rearrangements |
|---|
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | EDF1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | EDF1 |
| dbVar | EDF1 |
| ClinVar | EDF1 |
| 1000_Genomes | EDF1 |
| Exome Variant Server | EDF1 |
| ExAC (Exome Aggregation Consortium) | EDF1 (select the gene name) |
| Genetic variants : HAPMAP | 8721 |
| Genomic Variants (DGV) | EDF1 [DGVbeta] |
| DECIPHER | EDF1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | EDF1 |
| Mutations |
|---|
| ICGC Data Portal | EDF1 |
| TCGA Data Portal | EDF1 |
| Broad Tumor Portal | EDF1 |
| OASIS Portal | EDF1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | EDF1 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | EDF1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search EDF1 |
| DgiDB (Drug Gene Interaction Database) | EDF1 |
| DoCM (Curated mutations) | EDF1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | EDF1 (select a term) |
| intoGen | EDF1 |
| Cancer3D | EDF1(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 605107 |
| Orphanet | |
| Medgen | EDF1 |
| Genetic Testing Registry | EDF1
|
| NextProt | O60869 [Medical] |
| TSGene | 8721 |
| GENETests | EDF1 |
| Target Validation | EDF1 |
| Huge Navigator |
EDF1 [HugePedia] |
| snp3D : Map Gene to Disease | 8721 |
| BioCentury BCIQ | EDF1 |
| ClinGen | EDF1 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 8721 |
| Chemical/Pharm GKB Gene | PA27604 |
| Clinical trial | EDF1 |
| Miscellaneous |
|---|
| canSAR (ICR) | EDF1 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 29 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | EDF1 |
| EVEX | EDF1 |
| GoPubMed | EDF1 |
| iHOP | EDF1 |
