Atlas of Genetics and Cytogenetics in Oncology and Haematology

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EDNRB (endothelin receptor type B)

Identity

Other namesABCDS
ET-B
ET-BR
ETB
ETBR
ETRB
HSCR
HSCR2
WS4A
HGNC (Hugo) EDNRB
LocusID (NCBI) 1910
Location 13q22.3
Location_base_pair Starts at 78469616 and ends at 78549664 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)EDNRB   3180
Entrez_Gene (NCBI)EDNRB  1910  endothelin receptor type B
Cards
GeneCards (Weizmann)EDNRB
Ensembl (Hinxton)ENSG00000136160 [Gene_View]  chr13:78469616-78549664 [Contig_View]  EDNRB [Vega]
AceView (NCBI)EDNRB
Genatlas (Paris)EDNRB
SOURCE (Stanford)NM_000115 NM_001122659 NM_001201397 NM_003991
Genomic and cartography
GoldenPath (UCSC)EDNRB  -  13q22.3   chr13:78469616-78549664 -  13q22.3   [Description]    (hg19-Feb_2009)
EnsemblEDNRB - 13q22.3 [CytoView]
Mapping of homologs : NCBIEDNRB [Mapview]
OMIM131244   277580   600155   600501   
Gene and transcription
Genbank (Entrez)AB209198 AF114165 AK290699 AY275463 BC014472
RefSeq transcript (SRS)NM_000115 NM_001122659 NM_001201397 NM_003991
RefSeq transcript (Entrez)NM_000115 NM_001122659 NM_001201397 NM_003991
RefSeq genomic (SRS)AC_000145 NC_000013 NC_018924 NG_011630 NT_024524 NW_001838082 NW_004078077
RefSeq genomic (Entrez)AC_000145 NC_000013 NC_018924 NG_011630 NT_024524 NW_001838082 NW_004078077
Consensus coding sequences : CCDS (NCBI)EDNRB
Cluster EST : UnigeneHs.82002 [ SRS ] Hs.82002 [ NCBI ]
CGAP (NCI)Hs.82002
Alternative Splicing : Fast-db (Paris)GSHG0008557
Alternative Splicing GalleryENSG00000136160
Gene ExpressionEDNRB [ NCBI-GEO ]   EDNRB [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP24530 (SRS) P24530 (Uniprot)
NextProtP24530
With graphics : InterProP24530
Splice isoforms : SwissVarP24530(Swissvar)
Domaine pattern : Prosite (SRS)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (SRS)7TM_GPCR_Rhodpsn    Endthln_rcpt    ETB_rcpt    GPCR_Rhodpsn_supfam   
Domains : Interpro (EBI)7TM_GPCR_Rhodpsn    Endthln_rcpt    ETB_rcpt    GPCR_Rhodpsn_supfam   
Related proteins : CluSTrP24530
Domain families : Pfam (SRS)7tm_1 (PF00001)   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
DMDM1910
Blocks (Seattle)P24530
Human Protein AtlasENSG00000136160
HPRD08834
IPIIPI00029123   IPI00218197   IPI00412464   
Protein Interaction databases
DIP (DOE-UCLA)P24530
IntAct (EBI)P24530
FunCoupENSG00000136160
REACTOMEEDNRB
Protein Interaction Database1910
BioGRIDEDNRB
InParanoidP24530
Interologous Interaction database P24530
IntegromeDBEDNRB
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)EDNRB
SNP (GeneSNP Utah)EDNRB
SNP : HGBaseEDNRB
Genetic variants : HAPMAPEDNRB
Somatic Mutations in Cancer : COSMICEDNRB 
CONAN: Copy Number AnalysisEDNRB 
Mutations and Diseases : HGMDEDNRB
OMIM131244    277580    600155    600501   
GENETests131244    277580    600155    600501   
Disease Genetic AssociationEDNRB
Huge Navigator EDNRB [HugePedia]  EDNRB [HugeCancerGEM]
Genomic VariantsEDNRB  EDNRB [DGVbeta]
snp3D : Map Gene to Disease1910
General knowledge
Homologs : HomoloGeneEDNRB
Homology/Alignments : Family Browser (UCSC)EDNRB
Phylogenetic Trees/Animal Genes : TreeFamEDNRB
Chemical/Protein Interactions : CTD1910
Chemical/Pharm GKB GenePA27618
Clinical trialEDNRB
Cancer Resource (Charite)ENSG00000136160
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  neural crest cell migration  endothelin receptor activity  endothelin receptor activity  plasma membrane  integral to plasma membrane  regulation of pH  cell surface receptor signaling pathway  negative regulation of adenylate cyclase activity  phospholipase C-activating G-protein coupled receptor signaling pathway  nervous system development  peripheral nervous system development  posterior midgut development  regulation of blood pressure  negative regulation of neuron maturation  vein smooth muscle contraction  peptide hormone binding  melanocyte differentiation  negative regulation of cellular protein metabolic process  enteric smooth muscle cell differentiation  vasoconstriction  macrophage chemotaxis  enteric nervous system development  endothelin receptor signaling pathway  endothelin receptor signaling pathway  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  neural crest cell migration  endothelin receptor activity  endothelin receptor activity  plasma membrane  integral to plasma membrane  regulation of pH  cell surface receptor signaling pathway  negative regulation of adenylate cyclase activity  phospholipase C-activating G-protein coupled receptor signaling pathway  nervous system development  peripheral nervous system development  posterior midgut development  regulation of blood pressure  negative regulation of neuron maturation  vein smooth muscle contraction  peptide hormone binding  melanocyte differentiation  negative regulation of cellular protein metabolic process  enteric smooth muscle cell differentiation  vasoconstriction  macrophage chemotaxis  enteric nervous system development  endothelin receptor signaling pathway  endothelin receptor signaling pathway  
Pathways : BIOCARTARole of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy [Genes]   
Pathways : KEGGNeuroactive ligand-receptor interactionCalcium signaling pathway
Other databases
Probes
Litterature
PubMed156 Pubmed reference(s) in Entrez
PubGeneEDNRB
iHOPEDNRB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:46:39 CEST 2013
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