| Nomenclature |
|---|
| HGNC (Hugo) | EED 3188 |
| Cards |
|---|
| Entrez_Gene (NCBI) | EED 8726 embryonic ectoderm development |
| Aliases | HEED; WAIT1 |
| GeneCards (Weizmann) | EED |
| Ensembl hg19 (Hinxton) | ENSG00000074266 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000074266 [Gene_View] chr11:86244384-86278810 [Contig_View] EED [Vega] |
| ICGC DataPortal | ENSG00000074266 |
| TCGA cBioPortal | EED |
| AceView (NCBI) | EED |
| Genatlas (Paris) | EED |
| WikiGenes | 8726 |
| SOURCE (Princeton) | EED |
| Genetics Home Reference (NIH) | EED |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | EED - chr11:86244384-86278810 + 11q14.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | EED - 11q14.2 [Description] (hg19-Feb_2009) |
| Ensembl | EED - 11q14.2 [CytoView hg19] EED - 11q14.2 [CytoView hg38] |
| Mapping of homologs : NCBI | EED [Mapview hg19] EED [Mapview hg38] |
| OMIM | 605984 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AA811323 AF070418 AF078933 AF080227 AF099032 |
| RefSeq transcript (Entrez) | NM_001308007 NM_001330334 NM_003797 NM_152991 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | EED |
| Cluster EST : Unigene | Hs.528103 [ NCBI ] |
| CGAP (NCI) | Hs.528103 |
| Alternative Splicing Gallery | ENSG00000074266 |
| Gene Expression | EED [ NCBI-GEO ] EED [ EBI - ARRAY_EXPRESS ]
EED [ SEEK ] EED [ MEM ] |
| Gene Expression Viewer (FireBrowse) | EED [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevisible | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 8726 |
| GTEX Portal (Tissue expression) | EED |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O75530 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O75530 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O75530 |
| Splice isoforms : SwissVar | O75530 |
| PhosPhoSitePlus | O75530 |
| Domaine pattern : Prosite (Expaxy) | WD_REPEATS_1 (PS00678) WD_REPEATS_2 (PS50082) WD_REPEATS_REGION (PS50294) |
| Domains : Interpro (EBI) | WD40/YVTN_repeat-like_dom WD40_repeat WD40_repeat_CS WD40_repeat_dom |
| Domain families : Pfam (Sanger) | WD40 (PF00400) |
| Domain families : Pfam (NCBI) | pfam00400 |
| Domain families : Smart (EMBL) | WD40 (SM00320) |
| Conserved Domain (NCBI) | EED |
| DMDM Disease mutations | 8726 |
| Blocks (Seattle) | EED |
| PDB (SRS) | 3IIW 3IIY 3IJ0 3IJ1 3IJC 3JPX 3JZG 3JZH 3JZN 3K26 3K27 4X3E 5GSA 5H13 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5K0M 5TTW 5U5H 5U5K 5U5T 5U62 |
| PDB (PDBSum) | 3IIW 3IIY 3IJ0 3IJ1 3IJC 3JPX 3JZG 3JZH 3JZN 3K26 3K27 4X3E 5GSA 5H13 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5K0M 5TTW 5U5H 5U5K 5U5T 5U62 |
| PDB (IMB) | 3IIW 3IIY 3IJ0 3IJ1 3IJC 3JPX 3JZG 3JZH 3JZN 3K26 3K27 4X3E 5GSA 5H13 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5K0M 5TTW 5U5H 5U5K 5U5T 5U62 |
| PDB (RSDB) | 3IIW 3IIY 3IJ0 3IJ1 3IJC 3JPX 3JZG 3JZH 3JZN 3K26 3K27 4X3E 5GSA 5H13 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5K0M 5TTW 5U5H 5U5K 5U5T 5U62 |
| Structural Biology KnowledgeBase | 3IIW 3IIY 3IJ0 3IJ1 3IJC 3JPX 3JZG 3JZH 3JZN 3K26 3K27 4X3E 5GSA 5H13 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5K0M 5TTW 5U5H 5U5K 5U5T 5U62 |
| SCOP (Structural Classification of Proteins) | 3IIW 3IIY 3IJ0 3IJ1 3IJC 3JPX 3JZG 3JZH 3JZN 3K26 3K27 4X3E 5GSA 5H13 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5K0M 5TTW 5U5H 5U5K 5U5T 5U62 |
| CATH (Classification of proteins structures) | 3IIW 3IIY 3IJ0 3IJ1 3IJC 3JPX 3JZG 3JZH 3JZN 3K26 3K27 4X3E 5GSA 5H13 5H14 5H15 5H17 5H19 5H24 5H25 5HYN 5IJ7 5IJ8 5K0M 5TTW 5U5H 5U5K 5U5T 5U62 |
| Superfamily | O75530 |
| Human Protein Atlas | ENSG00000074266 |
| Peptide Atlas | O75530 |
| HPRD | 09343 |
| IPI | IPI00395515 IPI00432040 IPI00171248 IPI00979143 IPI00975934 IPI00976520 IPI00977098 IPI00978431 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O75530 |
| IntAct (EBI) | O75530 |
| FunCoup | ENSG00000074266 |
| BioGRID | EED |
| STRING (EMBL) | EED |
| ZODIAC | EED |
| Ontologies - Pathways |
|---|
| QuickGO | O75530 |
| Ontology : AmiGO | negative regulation of transcription from RNA polymerase II promoter RNA polymerase II core promoter proximal region sequence-specific DNA binding sex chromatin chromatin binding protein binding nucleus nucleoplasm nucleoplasm cytosol regulation of gene expression by genetic imprinting transcription, DNA-templated spinal cord development ESC/E(Z) complex histone methyltransferase activity histone methyltransferase activity identical protein binding pronucleus negative regulation of gene expression, epigenetic negative regulation of transcription, DNA-templated histone methyltransferase activity (H3-K27 specific) positive regulation of histone H3-K27 methylation histone H3-K27 methylation regulation of adaxial/abaxial pattern formation |
| Ontology : EGO-EBI | negative regulation of transcription from RNA polymerase II promoter RNA polymerase II core promoter proximal region sequence-specific DNA binding sex chromatin chromatin binding protein binding nucleus nucleoplasm nucleoplasm cytosol regulation of gene expression by genetic imprinting transcription, DNA-templated spinal cord development ESC/E(Z) complex histone methyltransferase activity histone methyltransferase activity identical protein binding pronucleus negative regulation of gene expression, epigenetic negative regulation of transcription, DNA-templated histone methyltransferase activity (H3-K27 specific) positive regulation of histone H3-K27 methylation histone H3-K27 methylation regulation of adaxial/abaxial pattern formation |
| Pathways : BIOCARTA | The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails [Genes] |
| NDEx Network | EED |
| Atlas of Cancer Signalling Network | EED |
| Wikipedia pathways | EED |
| Orthology - Evolution |
|---|
| OrthoDB | 8726 |
| GeneTree (enSembl) | ENSG00000074266 |
| Phylogenetic Trees/Animal Genes : TreeFam | EED |
| HOVERGEN | O75530 |
| HOGENOM | O75530 |
| Homologs : HomoloGene | EED |
| Homology/Alignments : Family Browser (UCSC) | EED |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | NSF/EED [17q21.31/11q14.2] [t(11;17)(q14;q21)] |
| Fusion: TCGA | NSF 17q21.31 EED 11q14.2 PRAD |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | EED [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | EED |
| dbVar | EED |
| ClinVar | EED |
| 1000_Genomes | EED |
| Exome Variant Server | EED |
| ExAC (Exome Aggregation Consortium) | EED (select the gene name) |
| Genetic variants : HAPMAP | 8726 |
| Genomic Variants (DGV) | EED [DGVbeta] |
| DECIPHER | EED [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | EED |
| Mutations |
|---|
| ICGC Data Portal | EED |
| TCGA Data Portal | EED |
| Broad Tumor Portal | EED |
| OASIS Portal | EED [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | EED [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | EED |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search EED |
| DgiDB (Drug Gene Interaction Database) | EED |
| DoCM (Curated mutations) | EED (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | EED (select a term) |
| intoGen | EED |
| Cancer3D | EED(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 605984 |
| Orphanet | |
| Medgen | EED |
| Genetic Testing Registry | EED
|
| NextProt | O75530 [Medical] |
| TSGene | 8726 |
| GENETests | EED |
| Target Validation | EED |
| Huge Navigator |
EED [HugePedia] |
| snp3D : Map Gene to Disease | 8726 |
| BioCentury BCIQ | EED |
| ClinGen | EED |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 8726 |
| Chemical/Pharm GKB Gene | PA27624 |
| Clinical trial | EED |
| Miscellaneous |
|---|
| canSAR (ICR) | EED (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 83 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | EED |
| EVEX | EED |
| GoPubMed | EED |
| iHOP | EED |
