Atlas of Genetics and Cytogenetics in Oncology and Haematology


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EEF1AKMT2 (EEF1A lysine methyltransferase 2)

Identity

Alias_namesC10orf138
METTL10
chromosome 10 open reading frame 138
methyltransferase like 10
Alias_symbol (synonym)Efm4
Other alias
HGNC (Hugo) EEF1AKMT2
LocusID (NCBI) 399818
Atlas_Id 79500
Location 10q26.13  [Link to chromosome band 10q26]
Location_base_pair Starts at 124757831 and ends at 124791941 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EEF1AKMT2   33787
Cards
Entrez_Gene (NCBI)EEF1AKMT2  399818  EEF1A lysine methyltransferase 2
AliasesC10orf138; Efm4; METTL10
GeneCards (Weizmann)EEF1AKMT2
Ensembl hg19 (Hinxton)ENSG00000203791 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000203791 [Gene_View]  chr10:124757831-124791941 [Contig_View]  EEF1AKMT2 [Vega]
ICGC DataPortalENSG00000203791
TCGA cBioPortalEEF1AKMT2
AceView (NCBI)EEF1AKMT2
Genatlas (Paris)EEF1AKMT2
WikiGenes399818
SOURCE (Princeton)EEF1AKMT2
Genetics Home Reference (NIH)EEF1AKMT2
Genomic and cartography
GoldenPath hg38 (UCSC)EEF1AKMT2  -     chr10:124757831-124791941 -  10q26.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EEF1AKMT2  -     10q26.13   [Description]    (hg19-Feb_2009)
EnsemblEEF1AKMT2 - 10q26.13 [CytoView hg19]  EEF1AKMT2 - 10q26.13 [CytoView hg38]
Mapping of homologs : NCBIEEF1AKMT2 [Mapview hg19]  EEF1AKMT2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA776892 AF318345 AK022354 AL832292 BC026167
RefSeq transcript (Entrez)NM_001304467 NM_001304468 NM_212554
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EEF1AKMT2
Cluster EST : UnigeneHs.741365 [ NCBI ]
CGAP (NCI)Hs.741365
Alternative Splicing GalleryENSG00000203791
Gene ExpressionEEF1AKMT2 [ NCBI-GEO ]   EEF1AKMT2 [ EBI - ARRAY_EXPRESS ]   EEF1AKMT2 [ SEEK ]   EEF1AKMT2 [ MEM ]
Gene Expression Viewer (FireBrowse)EEF1AKMT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)399818
GTEX Portal (Tissue expression)EEF1AKMT2
Human Protein AtlasENSG00000203791-EEF1AKMT2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JPI9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JPI9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JPI9
Splice isoforms : SwissVarQ5JPI9
PhosPhoSitePlusQ5JPI9
Domains : Interpro (EBI)Efm4    Methyltranfer_dom    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Methyltransf_31 (PF13847)   
Domain families : Pfam (NCBI)pfam13847   
Conserved Domain (NCBI)EEF1AKMT2
DMDM Disease mutations399818
Blocks (Seattle)EEF1AKMT2
SuperfamilyQ5JPI9
Human Protein Atlas [tissue]ENSG00000203791-EEF1AKMT2 [tissue]
Peptide AtlasQ5JPI9
IPIIPI00887206   IPI00871222   IPI00383305   IPI01025226   
Protein Interaction databases
DIP (DOE-UCLA)Q5JPI9
IntAct (EBI)Q5JPI9
FunCoupENSG00000203791
BioGRIDEEF1AKMT2
STRING (EMBL)EEF1AKMT2
ZODIACEEF1AKMT2
Ontologies - Pathways
QuickGOQ5JPI9
Ontology : AmiGOnucleus  cytoplasm  cytosol  protein methylation  methyltransferase activity  protein-lysine N-methyltransferase activity  protein-lysine N-methyltransferase activity  peptidyl-lysine methylation  
Ontology : EGO-EBInucleus  cytoplasm  cytosol  protein methylation  methyltransferase activity  protein-lysine N-methyltransferase activity  protein-lysine N-methyltransferase activity  peptidyl-lysine methylation  
NDEx NetworkEEF1AKMT2
Atlas of Cancer Signalling NetworkEEF1AKMT2
Wikipedia pathwaysEEF1AKMT2
Orthology - Evolution
OrthoDB399818
GeneTree (enSembl)ENSG00000203791
Phylogenetic Trees/Animal Genes : TreeFamEEF1AKMT2
HOVERGENQ5JPI9
HOGENOMQ5JPI9
Homologs : HomoloGeneEEF1AKMT2
Homology/Alignments : Family Browser (UCSC)EEF1AKMT2
Gene fusions - Rearrangements
Tumor Fusion PortalEEF1AKMT2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEEF1AKMT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EEF1AKMT2
dbVarEEF1AKMT2
ClinVarEEF1AKMT2
1000_GenomesEEF1AKMT2 
Exome Variant ServerEEF1AKMT2
ExAC (Exome Aggregation Consortium)ENSG00000203791
GNOMAD BrowserENSG00000203791
Genetic variants : HAPMAP399818
Genomic Variants (DGV)EEF1AKMT2 [DGVbeta]
DECIPHEREEF1AKMT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEEF1AKMT2 
Mutations
ICGC Data PortalEEF1AKMT2 
TCGA Data PortalEEF1AKMT2 
Broad Tumor PortalEEF1AKMT2
OASIS PortalEEF1AKMT2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDEEF1AKMT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EEF1AKMT2
DgiDB (Drug Gene Interaction Database)EEF1AKMT2
DoCM (Curated mutations)EEF1AKMT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EEF1AKMT2 (select a term)
intoGenEEF1AKMT2
Cancer3DEEF1AKMT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETEEF1AKMT2
MedgenEEF1AKMT2
Genetic Testing Registry EEF1AKMT2
NextProtQ5JPI9 [Medical]
TSGene399818
GENETestsEEF1AKMT2
Target ValidationEEF1AKMT2
Huge Navigator EEF1AKMT2 [HugePedia]
snp3D : Map Gene to Disease399818
BioCentury BCIQEEF1AKMT2
ClinGenEEF1AKMT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD399818
Chemical/Pharm GKB GenePA162395769
Clinical trialEEF1AKMT2
Miscellaneous
canSAR (ICR)EEF1AKMT2 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEEF1AKMT2
EVEXEEF1AKMT2
GoPubMedEEF1AKMT2
iHOPEEF1AKMT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:21:29 CET 2017

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