Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EFL1 (elongation factor like GTPase 1)

Identity

Alias_namesEFTUD1
elongation factor Tu GTP binding domain containing 1
Alias_symbol (synonym)FLJ13119
FAM42A
HsT19294
RIA1
Other alias
HGNC (Hugo) EFL1
LocusID (NCBI) 79631
Atlas_Id 55587
Location 15q25.2  [Link to chromosome band 15q25]
Location_base_pair Starts at 82130220 and ends at 82262763 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EFL1 (15q25.2) / CDADC1 (13q14.2)EFL1 (15q25.2) / KHDRBS2 (6q11.1)FAM98B (15q14) / EFL1 (15q25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EFL1   25789
Cards
Entrez_Gene (NCBI)EFL1  79631  elongation factor like GTPase 1
AliasesEFTUD1; FAM42A; HsT19294; RIA1
GeneCards (Weizmann)EFL1
Ensembl hg19 (Hinxton)ENSG00000140598 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140598 [Gene_View]  chr15:82130220-82262763 [Contig_View]  EFL1 [Vega]
ICGC DataPortalENSG00000140598
TCGA cBioPortalEFL1
AceView (NCBI)EFL1
Genatlas (Paris)EFL1
WikiGenes79631
SOURCE (Princeton)EFL1
Genetics Home Reference (NIH)EFL1
Genomic and cartography
GoldenPath hg38 (UCSC)EFL1  -     chr15:82130220-82262763 -  15q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EFL1  -     15q25.2   [Description]    (hg19-Feb_2009)
EnsemblEFL1 - 15q25.2 [CytoView hg19]  EFL1 - 15q25.2 [CytoView hg38]
Mapping of homologs : NCBIEFL1 [Mapview hg19]  EFL1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK023181 AK056656 AK300348 BC014628 BC041565
RefSeq transcript (Entrez)NM_001040610 NM_001322844 NM_001322845 NM_024580
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EFL1
Cluster EST : UnigeneHs.459114 [ NCBI ]
CGAP (NCI)Hs.459114
Alternative Splicing GalleryENSG00000140598
Gene ExpressionEFL1 [ NCBI-GEO ]   EFL1 [ EBI - ARRAY_EXPRESS ]   EFL1 [ SEEK ]   EFL1 [ MEM ]
Gene Expression Viewer (FireBrowse)EFL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79631
GTEX Portal (Tissue expression)EFL1
Human Protein AtlasENSG00000140598-EFL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z2Z2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z2Z2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z2Z2
Splice isoforms : SwissVarQ7Z2Z2
PhosPhoSitePlusQ7Z2Z2
Domaine pattern : Prosite (Expaxy)G_TR_2 (PS51722)   
Domains : Interpro (EBI)EFG_III-V    EFG_V    P-loop_NTPase    Ribosomal_S5_D2-typ_fold    Ribosomal_S5_D2-typ_fold_subgr    Small_GTP-bd_dom    TF_GTP-bd_dom    Transl_B-barrel   
Domain families : Pfam (Sanger)EFG_C (PF00679)    EFG_II (PF14492)   
Domain families : Pfam (NCBI)pfam00679    pfam14492   
Domain families : Smart (EMBL)EFG_C (SM00838)  
Conserved Domain (NCBI)EFL1
DMDM Disease mutations79631
Blocks (Seattle)EFL1
PDB (SRS)5ANB    5ANC   
PDB (PDBSum)5ANB    5ANC   
PDB (IMB)5ANB    5ANC   
PDB (RSDB)5ANB    5ANC   
Structural Biology KnowledgeBase5ANB    5ANC   
SCOP (Structural Classification of Proteins)5ANB    5ANC   
CATH (Classification of proteins structures)5ANB    5ANC   
SuperfamilyQ7Z2Z2
Human Protein Atlas [tissue]ENSG00000140598-EFL1 [tissue]
Peptide AtlasQ7Z2Z2
HPRD07812
IPIIPI00293026   IPI00759768   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z2Z2
IntAct (EBI)Q7Z2Z2
FunCoupENSG00000140598
BioGRIDEFL1
STRING (EMBL)EFL1
ZODIACEFL1
Ontologies - Pathways
QuickGOQ7Z2Z2
Ontology : AmiGOtranslation elongation factor activity  GTPase activity  GTP binding  translational elongation  mature ribosome assembly  ribosome binding  
Ontology : EGO-EBItranslation elongation factor activity  GTPase activity  GTP binding  translational elongation  mature ribosome assembly  ribosome binding  
NDEx NetworkEFL1
Atlas of Cancer Signalling NetworkEFL1
Wikipedia pathwaysEFL1
Orthology - Evolution
OrthoDB79631
GeneTree (enSembl)ENSG00000140598
Phylogenetic Trees/Animal Genes : TreeFamEFL1
HOVERGENQ7Z2Z2
HOGENOMQ7Z2Z2
Homologs : HomoloGeneEFL1
Homology/Alignments : Family Browser (UCSC)EFL1
Gene fusions - Rearrangements
Tumor Fusion PortalEFL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEFL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EFL1
dbVarEFL1
ClinVarEFL1
1000_GenomesEFL1 
Exome Variant ServerEFL1
ExAC (Exome Aggregation Consortium)ENSG00000140598
GNOMAD BrowserENSG00000140598
Genetic variants : HAPMAP79631
Genomic Variants (DGV)EFL1 [DGVbeta]
DECIPHEREFL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEFL1 
Mutations
ICGC Data PortalEFL1 
TCGA Data PortalEFL1 
Broad Tumor PortalEFL1
OASIS PortalEFL1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDEFL1
BioMutasearch EFL1
DgiDB (Drug Gene Interaction Database)EFL1
DoCM (Curated mutations)EFL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EFL1 (select a term)
intoGenEFL1
Cancer3DEFL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETEFL1
MedgenEFL1
Genetic Testing Registry EFL1
NextProtQ7Z2Z2 [Medical]
TSGene79631
GENETestsEFL1
Target ValidationEFL1
Huge Navigator EFL1 [HugePedia]
snp3D : Map Gene to Disease79631
BioCentury BCIQEFL1
ClinGenEFL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79631
Chemical/Pharm GKB GenePA134902221
Clinical trialEFL1
Miscellaneous
canSAR (ICR)EFL1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEFL1
EVEXEFL1
GoPubMedEFL1
iHOPEFL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:11:37 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.