Identity
HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
EFL4,EPLG4,LERK4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1945
MIM: 601380
HGNC: 3224
Ensembl: ENSG00000243364
Variants:
dbSNP: 1945
ClinVar: 1945
TCGA: ENSG00000243364
COSMIC: EFNA4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000243364 | ENST00000359751 | P52798 |
| ENSG00000243364 | ENST00000368409 | P52798 |
| ENSG00000243364 | ENST00000427683 | P52798 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36404439 | 2022 | Interference of EFNA4 suppresses cell proliferation, invasion and angiogenesis in hepatocellular carcinoma by downregulating PYGO2. | 3 |
| 36404439 | 2022 | Interference of EFNA4 suppresses cell proliferation, invasion and angiogenesis in hepatocellular carcinoma by downregulating PYGO2. | 3 |
| 33436772 | 2021 | Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells. | 7 |
| 33436772 | 2021 | Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells. | 7 |
| 27374180 | 2016 | EphrinA4 plays a critical role in α4 and αL mediated survival of human CLL cells during extravasation. | 4 |
| 27374180 | 2016 | EphrinA4 plays a critical role in α4 and αL mediated survival of human CLL cells during extravasation. | 4 |
| 25070915 | 2014 | Ephrin-A3 and ephrin-A4 contribute to microglia-induced angiogenesis in brain endothelial cells. | 16 |
| 25070915 | 2014 | Ephrin-A3 and ephrin-A4 contribute to microglia-induced angiogenesis in brain endothelial cells. | 16 |
| 23686814 | 2013 | Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells. | 6 |
| 23686814 | 2013 | Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells. | 6 |
| 20071790 | 2010 | Ephrin A4 expression in osteosarcoma, impact on prognosis, and patient outcome. | 6 |
| 20643727 | 2010 | Prevalence and complications of single-gene and chromosomal disorders in craniosynostosis. | 87 |
| 20071790 | 2010 | Ephrin A4 expression in osteosarcoma, impact on prognosis, and patient outcome. | 6 |
| 20643727 | 2010 | Prevalence and complications of single-gene and chromosomal disorders in craniosynostosis. | 87 |
| 18819711 | 2009 | Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cells. | 17 |
Citation
Dessen P
EFNA4 (ephrin A4)
Atlas Genet Cytogenet Oncol Haematol. 2010-01-01
Online version: http://atlasgeneticsoncology.org/gene/51304/efna4
