EGFL6 (EGF like domain multiple 6)

2003-06-01  

Identity

HGNC
LOCATION
Xp22.2
LOCUSID
ALIAS
MAEG,W80
FUSION GENES

Other Information

Locus ID:

NCBI: 25975
MIM: 300239
HGNC: 3235
Ensembl: ENSG00000198759

Variants:

dbSNP: 25975
ClinVar: 25975
TCGA: ENSG00000198759
COSMIC: EGFL6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198759ENST00000361306Q8IUX8
ENSG00000198759ENST00000380602Q8IUX8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
278031062016EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells.26
232851632012Analysis of gene expression profiling in meningioma: deregulated signaling pathways associated with meningioma and EGFL6 overexpression in benign meningioma tissue and serum.25
205747862010EGFL6 is increasingly expressed in human obesity and promotes proliferation of adipose tissue-derived stromal vascular cells.11
285398172017High Level of Plasma EGFL6 Is Associated with Clinicopathological Characteristics in Patients with Oral Squamous Cell Carcinoma.5
304440692018Elevated EGFL6 modulates cell metastasis and growth via AKT pathway in nasopharyngeal carcinoma.3
304554282019EGFL6 promotes breast cancer by simultaneously enhancing cancer cell metastasis and stimulating tumor angiogenesis.3
299343892018Validation of EGFL6 expression as a prognostic marker in patients with lung adenocarcinoma in Taiwan: a retrospective study.2
306939732019EGFL6 promotes cell proliferation in colorectal cancer via regulation of the WNT/β-catenin pathway.2
180383282008Absence of GNAS and EGFL6 mutations in common human cancers.1
303956902019Identification of genes with universally upregulated or downregulated expressions in colorectal cancer.1

Citation

Dessen P

EGFL6 (EGF like domain multiple 6)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40418/egfl6