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EGFLAM (EGF like, fibronectin type III and laminin G domains)

Identity

Alias_namesEGF-like, fibronectin type III and laminin G domains
Alias_symbol (synonym)FLJ39155
AGRINL
AGRNL
PIKA
Other alias
HGNC (Hugo) EGFLAM
LocusID (NCBI) 133584
Atlas_Id 62756
Location 5p13.2  [Link to chromosome band 5p13]
Location_base_pair Starts at 38258409 and ends at 38465480 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EGFLAM (5p13.2) / EGFLAM (5p13.2)EGFLAM (5p13.2) / INPP4B (4q31.21)SLC30A6 (2p22.3) / EGFLAM (5p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EGFLAM   26810
Cards
Entrez_Gene (NCBI)EGFLAM  133584  EGF like, fibronectin type III and laminin G domains
AliasesAGRINL; AGRNL; PIKA
GeneCards (Weizmann)EGFLAM
Ensembl hg19 (Hinxton)ENSG00000164318 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164318 [Gene_View]  chr5:38258409-38465480 [Contig_View]  EGFLAM [Vega]
ICGC DataPortalENSG00000164318
TCGA cBioPortalEGFLAM
AceView (NCBI)EGFLAM
Genatlas (Paris)EGFLAM
WikiGenes133584
SOURCE (Princeton)EGFLAM
Genetics Home Reference (NIH)EGFLAM
Genomic and cartography
GoldenPath hg38 (UCSC)EGFLAM  -     chr5:38258409-38465480 +  5p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EGFLAM  -     5p13.2   [Description]    (hg19-Feb_2009)
EnsemblEGFLAM - 5p13.2 [CytoView hg19]  EGFLAM - 5p13.2 [CytoView hg38]
Mapping of homologs : NCBIEGFLAM [Mapview hg19]  EGFLAM [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK092479 AK092994 AK096474 AK097549 AK291602
RefSeq transcript (Entrez)NM_001205301 NM_152403 NM_182798 NM_182799 NM_182801
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EGFLAM
Cluster EST : UnigeneHs.20103 [ NCBI ]
CGAP (NCI)Hs.20103
Alternative Splicing GalleryENSG00000164318
Gene ExpressionEGFLAM [ NCBI-GEO ]   EGFLAM [ EBI - ARRAY_EXPRESS ]   EGFLAM [ SEEK ]   EGFLAM [ MEM ]
Gene Expression Viewer (FireBrowse)EGFLAM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)133584
GTEX Portal (Tissue expression)EGFLAM
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ63HQ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ63HQ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ63HQ2
Splice isoforms : SwissVarQ63HQ2
PhosPhoSitePlusQ63HQ2
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    FN3 (PS50853)    LAM_G_DOMAIN (PS50025)   
Domains : Interpro (EBI)ConA-like_dom    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    FN3_dom    Ig-like_fold    Laminin_G   
Domain families : Pfam (Sanger)EGF (PF00008)    fn3 (PF00041)    Laminin_G_1 (PF00054)    Laminin_G_2 (PF02210)   
Domain families : Pfam (NCBI)pfam00008    pfam00041    pfam00054    pfam02210   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  FN3 (SM00060)  LamG (SM00282)  
Conserved Domain (NCBI)EGFLAM
DMDM Disease mutations133584
Blocks (Seattle)EGFLAM
SuperfamilyQ63HQ2
Human Protein AtlasENSG00000164318
Peptide AtlasQ63HQ2
HPRD13433
IPIIPI00470484   IPI00743096   IPI00376634   IPI00334254   IPI00867652   IPI01014141   IPI00968230   IPI00966260   
Protein Interaction databases
DIP (DOE-UCLA)Q63HQ2
IntAct (EBI)Q63HQ2
FunCoupENSG00000164318
BioGRIDEGFLAM
STRING (EMBL)EGFLAM
ZODIACEGFLAM
Ontologies - Pathways
QuickGOQ63HQ2
Ontology : AmiGOcalcium ion binding  glycosaminoglycan binding  basement membrane  interstitial matrix  positive regulation of cell-substrate adhesion  peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan  cell junction  extracellular matrix organization  synapse  
Ontology : EGO-EBIcalcium ion binding  glycosaminoglycan binding  basement membrane  interstitial matrix  positive regulation of cell-substrate adhesion  peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan  cell junction  extracellular matrix organization  synapse  
NDEx NetworkEGFLAM
Atlas of Cancer Signalling NetworkEGFLAM
Wikipedia pathwaysEGFLAM
Orthology - Evolution
OrthoDB133584
GeneTree (enSembl)ENSG00000164318
Phylogenetic Trees/Animal Genes : TreeFamEGFLAM
HOVERGENQ63HQ2
HOGENOMQ63HQ2
Homologs : HomoloGeneEGFLAM
Homology/Alignments : Family Browser (UCSC)EGFLAM
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEGFLAM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EGFLAM
dbVarEGFLAM
ClinVarEGFLAM
1000_GenomesEGFLAM 
Exome Variant ServerEGFLAM
ExAC (Exome Aggregation Consortium)EGFLAM (select the gene name)
Genetic variants : HAPMAP133584
Genomic Variants (DGV)EGFLAM [DGVbeta]
DECIPHEREGFLAM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEGFLAM 
Mutations
ICGC Data PortalEGFLAM 
TCGA Data PortalEGFLAM 
Broad Tumor PortalEGFLAM
OASIS PortalEGFLAM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEGFLAM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEGFLAM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EGFLAM
DgiDB (Drug Gene Interaction Database)EGFLAM
DoCM (Curated mutations)EGFLAM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EGFLAM (select a term)
intoGenEGFLAM
Cancer3DEGFLAM(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenEGFLAM
Genetic Testing Registry EGFLAM
NextProtQ63HQ2 [Medical]
TSGene133584
GENETestsEGFLAM
Target ValidationEGFLAM
Huge Navigator EGFLAM [HugePedia]
snp3D : Map Gene to Disease133584
BioCentury BCIQEGFLAM
ClinGenEGFLAM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD133584
Chemical/Pharm GKB GenePA147358056
Clinical trialEGFLAM
Miscellaneous
canSAR (ICR)EGFLAM (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEGFLAM
EVEXEGFLAM
GoPubMedEGFLAM
iHOPEGFLAM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:06:55 CEST 2017

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