Atlas of Genetics and Cytogenetics in Oncology and Haematology


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EGFR (epidermal growth factor receptor)

Identity

Other namesERBB
ERBB1
HER1
NISBD2
PIG61
mENA
HGNC (Hugo) EGFR
LocusID (NCBI) 1956
Atlas_Id 147
Location 7p11.2
Location_base_pair Starts at 55086725 and ends at 55275031 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2015)
EGFR 7p11.2 / ACADM 1p31.1EGFR 7p11.2 / DYM 18q21.1EGFR 7p11.2 / ERP44 9q31.1
EGFR 7p11.2 / GNS 12q14.3EGFR 7p11.2 / PPM1H 12q14.1EGFR 7p11.2 / SEPT14 7p11.2
MDM2 12q15 / EGFR 7p11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [36219+1]
  idic(7)(q11.2)
t(1;9)(p34;q34) SFPQ/ABL1
t(9;13)(p12;q21) PAX5/DACH1

Other Solid tumors implicated (Data extracted from papers in the Atlas)
  Thyroid: Anaplastic (undifferentiated) carcinoma
Nervous system: Astrocytic tumors
Colon: Colorectal adenocarcinoma
Breast: Ductal carcinoma
Fallopian tube tumors: an overview
Gastric Tumors: an overview
Nervous System: Glioma: an overview
Head and Neck: Squamous cell carcinoma: an overview
Gallbladder: Intrahepatic cholangiocarcinoma
Lung: Non-small cell carcinoma with inv(2)(p21p23) EML4/ALK
Head and Neck: Laryngeal tumors: an overview
Head and Neck: Laryngeal squamous cell carcinoma
Lung: Non-small cell carcinoma
Thyroid: Medullary carcinoma
Head and Neck: Oral squamous cell carcinoma
Ovarian tumours : an overview
Ovary: Epithelial tumors
Pancreatic tumors: an overview
Head and Neck: Salivary gland tumors: an overview
Soft tissue tumors: an overview
Squamous cell cancer
Lung: Adenocarcinoma with t(6;12)(q22;q14.1) LRIG3/ROS1
Head and Neck: Thymus: Thymoma: an overview
Lung: Translocations in Adenocarcinoma
Lung: Translocations in Squamous Cell Carcinoma

External links

Nomenclature
HGNC (Hugo)EGFR   3236
Cards
Entrez_Gene (NCBI)EGFR  1956  epidermal growth factor receptor
GeneCards (Weizmann)EGFR
Ensembl hg19 (Hinxton)ENSG00000146648 [Gene_View]  chr7:55086725-55275031 [Contig_View]  EGFR [Vega]
Ensembl hg38 (Hinxton)ENSG00000146648 [Gene_View]  chr7:55086725-55275031 [Contig_View]  EGFR [Vega]
ICGC DataPortalENSG00000146648
TCGA cBioPortalEGFR
AceView (NCBI)EGFR
Genatlas (Paris)EGFR
WikiGenes1956
SOURCE (Princeton)EGFR
Genomic and cartography
GoldenPath hg19 (UCSC)EGFR  -     chr7:55086725-55275031 +  7p11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)EGFR  -     7p11.2   [Description]    (hg38-Dec_2013)
EnsemblEGFR - 7p11.2 [CytoView hg19]  EGFR - 7p11.2 [CytoView hg38]
Mapping of homologs : NCBIEGFR [Mapview hg19]  EGFR [Mapview hg38]
OMIM131550   211980   616069   
Gene and transcription
Genbank (Entrez)AB209442 AF125253 AF277897 AI217671 AK127817
RefSeq transcript (Entrez)NM_005228 NM_201282 NM_201283 NM_201284
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_007726 NT_007819 NW_004929330
Consensus coding sequences : CCDS (NCBI)EGFR
Cluster EST : UnigeneHs.605083 [ NCBI ]
CGAP (NCI)Hs.605083
Alternative Splicing : Fast-db (Paris)GSHG0027358
Alternative Splicing GalleryENSG00000146648
Gene ExpressionEGFR [ NCBI-GEO ]     EGFR [ SEEK ]   EGFR [ MEM ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)1956
Protein : pattern, domain, 3D structure
UniProt/SwissProtP00533 (Uniprot)
NextProtP00533  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP00533
Splice isoforms : SwissVarP00533 (Swissvar)
Catalytic activity : Enzyme2.7.10.1 [ Enzyme-Expasy ]   2.7.10.1 [ Enzyme-SRS ]   2.7.10.1 [ IntEnz-EBI ]   2.7.10.1 [ PRIAM ]   2.7.10.1 [ BRENDA ]   2.7.10.1 [ KEGG ]   2.7.10.1 [ IUBMB ]
PhosPhoSitePlusP00533
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_TYR (PS00109)   
Domains : Interpro (EBI)Furin-like_Cys-rich_dom    Furin_repeat    Growth_fac_rcpt_N_dom    Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Rcpt_L-dom    Ser-Thr/Tyr_kinase_cat_dom    Tyr_kinase_AS    Tyr_kinase_cat_dom    Tyr_kinase_EGF/ERB/XmrK_rcpt   
Domain families : Pfam (Sanger)Furin-like (PF00757)    Pkinase_Tyr (PF07714)    Recep_L_domain (PF01030)   
Domain families : Pfam (NCBI)pfam00757    pfam07714    pfam01030   
Domain families : Smart (EMBL)FU (SM00261)  TyrKc (SM00219)  
DMDM Disease mutations1956
Blocks (Seattle)EGFR
PDB (SRS)1DNQ    1DNR    1IVO    1M14    1M17    1MOX    1NQL    1XKK    1YY9    1Z9I    2EB2    2EB3    2EXP    2EXQ    2GS2    2GS6    2GS7    2ITN    2ITO    2ITP    2ITQ    2ITT    2ITU    2ITV    2ITW    2ITX    2ITY    2ITZ    2J5E    2J5F    2J6M    2JIT    2JIU    2JIV    2KS1    2M0B    2M20    2RF9    2RFD    2RFE    2RGP    3B2U    3B2V    3BEL    3BUO    3C09    3G5V    3G5Y    3GOP    3GT8    3IKA    3LZB    3NJP    3OB2    3OP0    3P0Y    3PFV    3POZ    3QWQ    3UG1    3UG2    3VJN    3VJO    3VRP    3VRR    3W2O    3W2P    3W2Q    3W2R    3W2S    3W32    3W33    4G5J    4G5P    4HJO    4I1Z    4I20    4I21    4I22    4I23    4I24    4JQ7    4JQ8    4JR3    4JRV    4KRL    4KRM    4KRO    4KRP    4LI5    4LL0    4LQM    4LRM    4R5S    4RIW    4RIX    4RIY    4RJ4    4RJ5    4RJ6    4RJ7    4RJ8    4TKS    4WKQ    4WRG   
PDB (PDBSum)1DNQ    1DNR    1IVO    1M14    1M17    1MOX    1NQL    1XKK    1YY9    1Z9I    2EB2    2EB3    2EXP    2EXQ    2GS2    2GS6    2GS7    2ITN    2ITO    2ITP    2ITQ    2ITT    2ITU    2ITV    2ITW    2ITX    2ITY    2ITZ    2J5E    2J5F    2J6M    2JIT    2JIU    2JIV    2KS1    2M0B    2M20    2RF9    2RFD    2RFE    2RGP    3B2U    3B2V    3BEL    3BUO    3C09    3G5V    3G5Y    3GOP    3GT8    3IKA    3LZB    3NJP    3OB2    3OP0    3P0Y    3PFV    3POZ    3QWQ    3UG1    3UG2    3VJN    3VJO    3VRP    3VRR    3W2O    3W2P    3W2Q    3W2R    3W2S    3W32    3W33    4G5J    4G5P    4HJO    4I1Z    4I20    4I21    4I22    4I23    4I24    4JQ7    4JQ8    4JR3    4JRV    4KRL    4KRM    4KRO    4KRP    4LI5    4LL0    4LQM    4LRM    4R5S    4RIW    4RIX    4RIY    4RJ4    4RJ5    4RJ6    4RJ7    4RJ8    4TKS    4WKQ    4WRG   
PDB (IMB)1DNQ    1DNR    1IVO    1M14    1M17    1MOX    1NQL    1XKK    1YY9    1Z9I    2EB2    2EB3    2EXP    2EXQ    2GS2    2GS6    2GS7    2ITN    2ITO    2ITP    2ITQ    2ITT    2ITU    2ITV    2ITW    2ITX    2ITY    2ITZ    2J5E    2J5F    2J6M    2JIT    2JIU    2JIV    2KS1    2M0B    2M20    2RF9    2RFD    2RFE    2RGP    3B2U    3B2V    3BEL    3BUO    3C09    3G5V    3G5Y    3GOP    3GT8    3IKA    3LZB    3NJP    3OB2    3OP0    3P0Y    3PFV    3POZ    3QWQ    3UG1    3UG2    3VJN    3VJO    3VRP    3VRR    3W2O    3W2P    3W2Q    3W2R    3W2S    3W32    3W33    4G5J    4G5P    4HJO    4I1Z    4I20    4I21    4I22    4I23    4I24    4JQ7    4JQ8    4JR3    4JRV    4KRL    4KRM    4KRO    4KRP    4LI5    4LL0    4LQM    4LRM    4R5S    4RIW    4RIX    4RIY    4RJ4    4RJ5    4RJ6    4RJ7    4RJ8    4TKS    4WKQ    4WRG   
PDB (RSDB)1DNQ    1DNR    1IVO    1M14    1M17    1MOX    1NQL    1XKK    1YY9    1Z9I    2EB2    2EB3    2EXP    2EXQ    2GS2    2GS6    2GS7    2ITN    2ITO    2ITP    2ITQ    2ITT    2ITU    2ITV    2ITW    2ITX    2ITY    2ITZ    2J5E    2J5F    2J6M    2JIT    2JIU    2JIV    2KS1    2M0B    2M20    2RF9    2RFD    2RFE    2RGP    3B2U    3B2V    3BEL    3BUO    3C09    3G5V    3G5Y    3GOP    3GT8    3IKA    3LZB    3NJP    3OB2    3OP0    3P0Y    3PFV    3POZ    3QWQ    3UG1    3UG2    3VJN    3VJO    3VRP    3VRR    3W2O    3W2P    3W2Q    3W2R    3W2S    3W32    3W33    4G5J    4G5P    4HJO    4I1Z    4I20    4I21    4I22    4I23    4I24    4JQ7    4JQ8    4JR3    4JRV    4KRL    4KRM    4KRO    4KRP    4LI5    4LL0    4LQM    4LRM    4R5S    4RIW    4RIX    4RIY    4RJ4    4RJ5    4RJ6    4RJ7    4RJ8    4TKS    4WKQ    4WRG   
Structural Biology KnowledgeBase1DNQ    1DNR    1IVO    1M14    1M17    1MOX    1NQL    1XKK    1YY9    1Z9I    2EB2    2EB3    2EXP    2EXQ    2GS2    2GS6    2GS7    2ITN    2ITO    2ITP    2ITQ    2ITT    2ITU    2ITV    2ITW    2ITX    2ITY    2ITZ    2J5E    2J5F    2J6M    2JIT    2JIU    2JIV    2KS1    2M0B    2M20    2RF9    2RFD    2RFE    2RGP    3B2U    3B2V    3BEL    3BUO    3C09    3G5V    3G5Y    3GOP    3GT8    3IKA    3LZB    3NJP    3OB2    3OP0    3P0Y    3PFV    3POZ    3QWQ    3UG1    3UG2    3VJN    3VJO    3VRP    3VRR    3W2O    3W2P    3W2Q    3W2R    3W2S    3W32    3W33    4G5J    4G5P    4HJO    4I1Z    4I20    4I21    4I22    4I23    4I24    4JQ7    4JQ8    4JR3    4JRV    4KRL    4KRM    4KRO    4KRP    4LI5    4LL0    4LQM    4LRM    4R5S    4RIW    4RIX    4RIY    4RJ4    4RJ5    4RJ6    4RJ7    4RJ8    4TKS    4WKQ    4WRG   
SCOP (Structural Classification of Proteins)1DNQ    1DNR    1IVO    1M14    1M17    1MOX    1NQL    1XKK    1YY9    1Z9I    2EB2    2EB3    2EXP    2EXQ    2GS2    2GS6    2GS7    2ITN    2ITO    2ITP    2ITQ    2ITT    2ITU    2ITV    2ITW    2ITX    2ITY    2ITZ    2J5E    2J5F    2J6M    2JIT    2JIU    2JIV    2KS1    2M0B    2M20    2RF9    2RFD    2RFE    2RGP    3B2U    3B2V    3BEL    3BUO    3C09    3G5V    3G5Y    3GOP    3GT8    3IKA    3LZB    3NJP    3OB2    3OP0    3P0Y    3PFV    3POZ    3QWQ    3UG1    3UG2    3VJN    3VJO    3VRP    3VRR    3W2O    3W2P    3W2Q    3W2R    3W2S    3W32    3W33    4G5J    4G5P    4HJO    4I1Z    4I20    4I21    4I22    4I23    4I24    4JQ7    4JQ8    4JR3    4JRV    4KRL    4KRM    4KRO    4KRP    4LI5    4LL0    4LQM    4LRM    4R5S    4RIW    4RIX    4RIY    4RJ4    4RJ5    4RJ6    4RJ7    4RJ8    4TKS    4WKQ    4WRG   
CATH (Classification of proteins structures)1DNQ    1DNR    1IVO    1M14    1M17    1MOX    1NQL    1XKK    1YY9    1Z9I    2EB2    2EB3    2EXP    2EXQ    2GS2    2GS6    2GS7    2ITN    2ITO    2ITP    2ITQ    2ITT    2ITU    2ITV    2ITW    2ITX    2ITY    2ITZ    2J5E    2J5F    2J6M    2JIT    2JIU    2JIV    2KS1    2M0B    2M20    2RF9    2RFD    2RFE    2RGP    3B2U    3B2V    3BEL    3BUO    3C09    3G5V    3G5Y    3GOP    3GT8    3IKA    3LZB    3NJP    3OB2    3OP0    3P0Y    3PFV    3POZ    3QWQ    3UG1    3UG2    3VJN    3VJO    3VRP    3VRR    3W2O    3W2P    3W2Q    3W2R    3W2S    3W32    3W33    4G5J    4G5P    4HJO    4I1Z    4I20    4I21    4I22    4I23    4I24    4JQ7    4JQ8    4JR3    4JRV    4KRL    4KRM    4KRO    4KRP    4LI5    4LL0    4LQM    4LRM    4R5S    4RIW    4RIX    4RIY    4RJ4    4RJ5    4RJ6    4RJ7    4RJ8    4TKS    4WKQ    4WRG   
Human Protein AtlasENSG00000146648
Peptide AtlasP00533
HPRD00579
IPIIPI00018274   IPI00221346   IPI00221347   IPI00221348   IPI00930194   IPI00930693   IPI01026443   IPI00915452   IPI01013089   IPI01011440   IPI00930192   IPI00930294   IPI00956452   IPI00943104   IPI00924546   IPI00926683   
Protein Interaction databases
DIP (DOE-UCLA)P00533
IntAct (EBI)P00533
FunCoupENSG00000146648
BioGRIDEGFR
IntegromeDBEGFR
STRING (EMBL)EGFR
ZODIACEGFR
Ontologies - Pathways
QuickGOP00533
Ontology : AmiGOGolgi membrane  MAPK cascade  activation of MAPKK activity  ossification  embryonic placenta development  positive regulation of protein phosphorylation  hair follicle development  chromatin binding  double-stranded DNA binding  MAP kinase kinase kinase activity  protein tyrosine kinase activity  protein tyrosine kinase activity  protein tyrosine kinase activity  transmembrane receptor protein tyrosine kinase activity  receptor signaling protein tyrosine kinase activity  transmembrane signaling receptor activity  epidermal growth factor-activated receptor activity  epidermal growth factor-activated receptor activity  protein binding  ATP binding  extracellular space  nucleus  cytoplasm  endosome  endoplasmic reticulum membrane  plasma membrane  plasma membrane  focal adhesion  response to stress  signal transduction  signal transduction  cell surface receptor signaling pathway  epidermal growth factor receptor signaling pathway  epidermal growth factor receptor signaling pathway  activation of phospholipase C activity  small GTPase mediated signal transduction  Ras protein signal transduction  axon guidance  salivary gland morphogenesis  learning or memory  cell proliferation  positive regulation of cell proliferation  insulin receptor signaling pathway  fibroblast growth factor receptor signaling pathway  cell surface  endosome membrane  membrane  integral component of membrane  basolateral plasma membrane  single organismal cell-cell adhesion  peptidyl-tyrosine phosphorylation  peptidyl-tyrosine phosphorylation  peptidyl-tyrosine phosphorylation  peptidyl-tyrosine phosphorylation  enzyme binding  protein phosphatase binding  cerebral cortex cell migration  AP-2 adaptor complex  nitric-oxide synthase regulator activity  positive regulation of cell migration  ubiquitin protein ligase binding  positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle  early endosome membrane  nuclear membrane  positive regulation of catenin import into nucleus  Fc-epsilon receptor signaling pathway  negative regulation of epidermal growth factor receptor signaling pathway  negative regulation of protein catabolic process  positive regulation of phosphorylation  identical protein binding  activation of phospholipase A2 activity by calcium-mediated signaling  negative regulation of apoptotic process  receptor complex  positive regulation of MAP kinase activity  innate immune response  membrane raft  positive regulation of nitric oxide biosynthetic process  positive regulation of DNA repair  positive regulation of DNA replication  positive regulation of transcription from RNA polymerase II promoter  protein autophosphorylation  protein heterodimerization activity  vascular endothelial growth factor receptor signaling pathway  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  positive regulation of fibroblast proliferation  perinuclear region of cytoplasm  digestive tract morphogenesis  positive regulation of epithelial cell proliferation  regulation of peptidyl-tyrosine phosphorylation  regulation of nitric-oxide synthase activity  actin filament binding  protein insertion into membrane  positive regulation of protein kinase B signaling  morphogenesis of an epithelial fold  response to UV-A  positive regulation of ERK1 and ERK2 cascade  Shc-EGFR complex  cellular response to amino acid stimulus  cellular response to epidermal growth factor stimulus  cellular response to estradiol stimulus  multivesicular body, internal vesicle lumen  
Ontology : EGO-EBIGolgi membrane  MAPK cascade  activation of MAPKK activity  ossification  embryonic placenta development  positive regulation of protein phosphorylation  hair follicle development  chromatin binding  double-stranded DNA binding  MAP kinase kinase kinase activity  protein tyrosine kinase activity  protein tyrosine kinase activity  protein tyrosine kinase activity  transmembrane receptor protein tyrosine kinase activity  receptor signaling protein tyrosine kinase activity  transmembrane signaling receptor activity  epidermal growth factor-activated receptor activity  epidermal growth factor-activated receptor activity  protein binding  ATP binding  extracellular space  nucleus  cytoplasm  endosome  endoplasmic reticulum membrane  plasma membrane  plasma membrane  focal adhesion  response to stress  signal transduction  signal transduction  cell surface receptor signaling pathway  epidermal growth factor receptor signaling pathway  epidermal growth factor receptor signaling pathway  activation of phospholipase C activity  small GTPase mediated signal transduction  Ras protein signal transduction  axon guidance  salivary gland morphogenesis  learning or memory  cell proliferation  positive regulation of cell proliferation  insulin receptor signaling pathway  fibroblast growth factor receptor signaling pathway  cell surface  endosome membrane  membrane  integral component of membrane  basolateral plasma membrane  single organismal cell-cell adhesion  peptidyl-tyrosine phosphorylation  peptidyl-tyrosine phosphorylation  peptidyl-tyrosine phosphorylation  peptidyl-tyrosine phosphorylation  enzyme binding  protein phosphatase binding  cerebral cortex cell migration  AP-2 adaptor complex  nitric-oxide synthase regulator activity  positive regulation of cell migration  ubiquitin protein ligase binding  positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle  early endosome membrane  nuclear membrane  positive regulation of catenin import into nucleus  Fc-epsilon receptor signaling pathway  negative regulation of epidermal growth factor receptor signaling pathway  negative regulation of protein catabolic process  positive regulation of phosphorylation  identical protein binding  activation of phospholipase A2 activity by calcium-mediated signaling  negative regulation of apoptotic process  receptor complex  positive regulation of MAP kinase activity  innate immune response  membrane raft  positive regulation of nitric oxide biosynthetic process  positive regulation of DNA repair  positive regulation of DNA replication  positive regulation of transcription from RNA polymerase II promoter  protein autophosphorylation  protein heterodimerization activity  vascular endothelial growth factor receptor signaling pathway  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  positive regulation of fibroblast proliferation  perinuclear region of cytoplasm  digestive tract morphogenesis  positive regulation of epithelial cell proliferation  regulation of peptidyl-tyrosine phosphorylation  regulation of nitric-oxide synthase activity  actin filament binding  protein insertion into membrane  positive regulation of protein kinase B signaling  morphogenesis of an epithelial fold  response to UV-A  positive regulation of ERK1 and ERK2 cascade  Shc-EGFR complex  cellular response to amino acid stimulus  cellular response to epidermal growth factor stimulus  cellular response to estradiol stimulus  multivesicular body, internal vesicle lumen  
Pathways : BIOCARTATrefoil Factors Initiate Mucosal Healing [Genes]    Agrin in Postsynaptic Differentiation [Genes]    The role of FYVE-finger proteins in vesicle transport [Genes]    mCalpain and friends in Cell motility [Genes]    Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling [Genes]    CBL mediated ligand-induced downregulation of EGF receptors [Genes]    Keratinocyte Differentiation [Genes]    Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy [Genes]    Sprouty regulation of tyrosine kinase signals [Genes]    Telomeres, Telomerase, Cellular Aging, and Immortality [Genes]    Erk1/Erk2 Mapk Signaling pathway [Genes]    PTEN dependent cell cycle arrest and apoptosis [Genes]    EGF Signaling Pathway [Genes]    Map Kinase Inactivation of SMRT Corepressor [Genes]    Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling [Genes]    Role of ERBB2 in Signal Transduction and Oncology [Genes]   
Pathways : KEGGMAPK signaling pathway    ErbB signaling pathway    Ras signaling pathway    Rap1 signaling pathway    Calcium signaling pathway    Cytokine-cytokine receptor interaction    HIF-1 signaling pathway    FoxO signaling pathway    Endocytosis    PI3K-Akt signaling pathway    Dorso-ventral axis formation    Focal adhesion    Adherens junction    Gap junction    Regulation of actin cytoskeleton    GnRH signaling pathway    Estrogen signaling pathway    Epithelial cell signaling in Helicobacter pylori infection    Hepatitis C    Pathways in cancer    Proteoglycans in cancer    MicroRNAs in cancer    Pancreatic cancer    Endometrial cancer    Glioma    Prostate cancer    Melanoma    Bladder cancer    Non-small cell lung cancer   
Protein Interaction DatabaseEGFR
Atlas of Cancer Signalling NetworkEGFR
Wikipedia pathwaysEGFR
Orthology - Evolution
OrthoDB1956
GeneTree (enSembl)ENSG00000146648
Phylogenetic Trees/Animal Genes : TreeFamEGFR
Homologs : HomoloGeneEGFR
Homology/Alignments : Family Browser (UCSC)EGFR
Gene fusions - Rearrangements
Fusion: TCGAEGFR 7p11.2 ACADM 1p31.1 HNSC
Fusion: TCGAEGFR 7p11.2 DYM 18q21.1 HNSC
Fusion: TCGAEGFR 7p11.2 ERP44 9q31.1 GBM
Fusion: TCGAEGFR 7p11.2 GNS 12q14.3 GBM
Fusion: TCGAEGFR 7p11.2 PPM1H 12q14.1 GBM
Fusion: TCGAEGFR 7p11.2 SEPT14 7p11.2 GBM HNSC LGG
Fusion: TCGAMDM2 12q15 EGFR 7p11.2 GBM
Polymorphisms : SNP, variants
NCBI Variation ViewerEGFR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EGFR
dbVarEGFR
ClinVarEGFR
1000_GenomesEGFR 
Exome Variant ServerEGFR
Exome Aggregation Consortium (ExAC)ENSG00000146648
SNP (GeneSNP Utah)EGFR
SNP : HGBaseEGFR
Genetic variants : HAPMAPEGFR
Genomic Variants (DGV)EGFR [DGVbeta]
Mutations
ICGC Data PortalEGFR 
TCGA Data PortalEGFR 
Tumor PortalEGFR
TCGA Copy Number PortalEGFR
Cancer Gene: CensusEGFR 
Somatic Mutations in Cancer : COSMICEGFR 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch EGFR
DgiDB (Drug Gene Interaction Database)EGFR
DoCM (Curated mutations)EGFR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EGFR (select a term)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)7:55086725-55275031
CONAN: Copy Number AnalysisEGFR 
Mutations and Diseases : HGMDEGFR
OMIM131550    211980    616069   
MedgenEGFR
NextProtP00533 [Medical]
TSGene1956
GENETestsEGFR
Huge Navigator EGFR [HugePedia]  EGFR [HugeCancerGEM]
snp3D : Map Gene to Disease1956
BioCentury BCIQEGFR
General knowledge
Chemical/Protein Interactions : CTD1956
Chemical/Pharm GKB GenePA7360
Drug Sensitivity EGFR
Clinical trialEGFR
Other databases
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEGFR
GoPubMedEGFR
iHOPEGFR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sat Jan 16 18:32:30 CET 2016

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