| Nomenclature | | HGNC (Hugo) | EGLN2 14660 |
| Entrez_Gene (NCBI) | EGLN2 112398 egl nine homolog 2 (C. elegans) |
| Cards | | GeneCards (Weizmann) | EGLN2 |
| Ensembl (Hinxton) | ENSG00000269858 [Gene_View] chr19:41305334-41314346 [Contig_View] EGLN2 [Vega] |
| AceView (NCBI) | EGLN2 |
| Genatlas (Paris) | EGLN2 |
| SOURCE (Stanford) | NM_017555 NM_053046 NM_080732 |
| Genomic and cartography | | GoldenPath (UCSC) | EGLN2 - 19q13.2 chr19:41305334-41314346 + 19q13.2 [Description] (hg19-Feb_2009) |
| Ensembl | EGLN2 - 19q13.2 [CytoView] |
| Mapping of homologs : NCBI | EGLN2 [Mapview] |
| OMIM | 606424 |
| Gene and transcription |
| Genbank (Entrez) | AA994838 AJ310544 AK025396 AK026863 AK074408 |
| RefSeq transcript (SRS) | NM_017555 NM_053046 NM_080732 |
| RefSeq transcript (Entrez) | NM_017555 NM_053046 NM_080732 |
| RefSeq genomic (SRS) | AC_000151 NC_000019 NC_018930 NT_011109 NW_001838496 NW_004078099 |
| RefSeq genomic (Entrez) | AC_000151 NC_000019 NC_018930 NT_011109 NW_001838496 NW_004078099 |
| Consensus coding sequences : CCDS (NCBI) | EGLN2 |
| Cluster EST : Unigene | Hs.730737 [ SRS ] Hs.730737 [ NCBI ] |
| CGAP (NCI) | Hs.730737 |
| Alternative Splicing : Fast-db (Paris) | GSHG0014935 |
| Alternative Splicing Gallery | ENSG00000269858 |
| Gene Expression | EGLN2 [ NCBI-GEO ] EGLN2 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q96KS0 (SRS) Q96KS0 (Uniprot) |
| NextProt | Q96KS0 |
| With graphics : InterPro | Q96KS0 |
| Splice isoforms : SwissVar | Q96KS0(Swissvar) |
| Domaine pattern : Prosite (SRS) | FE2OG_OXY (PS51471) |
| Domaine pattern : Prosite (Expaxy) | FE2OG_OXY (PS51471) |
| Domains : Interpro (SRS) | Oxoglu/Fe-dep_dioxygenase Pro_4_hyd_alph |
| Domains : Interpro (EBI) | Oxoglu/Fe-dep_dioxygenase Pro_4_hyd_alph |
| Related proteins : CluSTr | Q96KS0 |
| Domain families : Pfam (SRS) | 2OG-FeII_Oxy_3 (PF13640) |
| Domain families : Pfam (Sanger) | 2OG-FeII_Oxy_3 (PF13640) |
| Domain families : Pfam (NCBI) | pfam13640 |
| Domain families : Smart (EMBL) | P4Hc (SM00702) |
| DMDM | 112398 |
| Blocks (Seattle) | Q96KS0 |
| Human Protein Atlas | ENSG00000269858 |
| HPRD | 06970 |
| IPI | IPI00074957 IPI00955972 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q96KS0 |
| IntAct (EBI) | Q96KS0 |
| FunCoup | ENSG00000269858 |
| REACTOME | EGLN2 |
| Protein Interaction Database | 112398 |
| BioGRID | EGLN2 |
| InParanoid | Q96KS0 |
| Interologous Interaction database | Q96KS0 |
| IntegromeDB | EGLN2 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | EGLN2 |
| SNP (GeneSNP Utah) | EGLN2 |
| SNP : HGBase | EGLN2 |
| Genetic variants : HAPMAP | EGLN2 |
| Somatic Mutations in Cancer : COSMIC | EGLN2 |
| CONAN: Copy Number Analysis | EGLN2 |
| Mutations and Diseases : HGMD | EGLN2 |
| OMIM | 606424 |
| GENETests | 606424 |
| Disease Genetic Association | EGLN2 |
| Huge Navigator |
EGLN2 [HugePedia] EGLN2 [HugeCancerGEM] |
| Genomic Variants | EGLN2 EGLN2 [DGVbeta] |
| ClinVar | EGLN2 |
| snp3D : Map Gene to Disease | 112398 |
| General knowledge |
|---|
| Homologs : HomoloGene | EGLN2 |
| Homology/Alignments : Family Browser (UCSC) | EGLN2 |
| Phylogenetic Trees/Animal Genes : TreeFam | EGLN2 |
| Catalytic activity : Enzyme | 1.14.11.29 [ Enzyme-Expasy ] 1.14.11.29 [ Enzyme-SRS ] 1.14.11.29 [ IntEnz-EBI ] 1.14.11.29 [ BRENDA ] 1.14.11.29 [ KEGG ] |
| Chemical/Protein Interactions : CTD | 112398 |
| Chemical/Pharm GKB Gene | PA27671 |
| Clinical trial | EGLN2 |
| Cancer Resource (Charite) | ENSG00000269858 |
| Ontology : AmiGO | regulation of cell growth response to hypoxia protein binding nucleus nucleoplasm ferrous iron binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors peptidyl-proline hydroxylation to 4-hydroxy-L-proline oxygen sensor activity intracellular estrogen receptor signaling pathway L-ascorbic acid binding peptidyl-proline 4-dioxygenase activity cellular response to stress regulation of neuron apoptotic process cell redox homeostasis positive regulation of protein catabolic process regulation of transcription from RNA polymerase II promoter in response to hypoxia cellular response to hypoxia |
| Ontology : EGO-EBI | regulation of cell growth response to hypoxia protein binding nucleus nucleoplasm ferrous iron binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors peptidyl-proline hydroxylation to 4-hydroxy-L-proline oxygen sensor activity intracellular estrogen receptor signaling pathway L-ascorbic acid binding peptidyl-proline 4-dioxygenase activity cellular response to stress regulation of neuron apoptotic process cell redox homeostasis positive regulation of protein catabolic process regulation of transcription from RNA polymerase II promoter in response to hypoxia cellular response to hypoxia |
| Other databases |
| Probes |
|---|
| Litterature | | PubMed | 67 Pubmed reference(s) in Entrez |
| PubGene | EGLN2 |
| iHOP | EGLN2 |
