EID1 (EP300 interacting inhibitor of differentiation 1)

2009-05-01  

Identity

HGNC
LOCATION
15q21.1
LOCUSID
ALIAS
C15orf3,CRI1,EID-1,IRO45620,PNAS-22,PTD014,RBP21

Other Information

Locus ID:

NCBI: 23741
MIM: 605894
HGNC: 1191
Ensembl: ENSG00000255302

Variants:

dbSNP: 23741
ClinVar: 23741
TCGA: ENSG00000255302
COSMIC: EID1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000255302ENST00000530028Q9Y6B2
ENSG00000255302ENST00000560490H0YN68

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
192764482009E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells.76
175590852007The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis.65
204867792011MicroRNA hsa-miR-138 inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells through adenovirus EID-1.60
221864212012Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease.14
243793972014Structural insights into gene repression by the orphan nuclear receptor SHP.12
241670732014Pcid2 inactivates developmental genes in human and mouse embryonic stem cells to sustain their pluripotency by modulation of EID1 stability.7
266317462015Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.3
266439092016Regulation of human subcutaneous adipocyte differentiation by EID1.3
260853302015FBXO21 mediates the ubiquitylation and proteasomal degradation of EID1.2

Citation

Dessen P

EID1 (EP300 interacting inhibitor of differentiation 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50892/eid1