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EIF1 (eukaryotic translation initiation factor 1)

Identity

Alias_symbol (synonym)EIF-1
ISO1
A121
SUI1
EIF1A
Other alias
HGNC (Hugo) EIF1
LocusID (NCBI) 10209
Atlas_Id 42448
Location 17q21.2  [Link to chromosome band 17q21]
Location_base_pair Starts at 41688875 and ends at 41691646 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EIF1 (17q21.2) / MED28 (4p15.32)EIF1 17q21.2 / MED28 4p15.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EIF1   3249
Cards
Entrez_Gene (NCBI)EIF1  10209  eukaryotic translation initiation factor 1
AliasesA121; EIF-1; EIF1A; ISO1; 
SUI1
GeneCards (Weizmann)EIF1
Ensembl hg19 (Hinxton)ENSG00000173812 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173812 [Gene_View]  chr17:41688875-41691646 [Contig_View]  EIF1 [Vega]
ICGC DataPortalENSG00000173812
TCGA cBioPortalEIF1
AceView (NCBI)EIF1
Genatlas (Paris)EIF1
WikiGenes10209
SOURCE (Princeton)EIF1
Genetics Home Reference (NIH)EIF1
Genomic and cartography
GoldenPath hg38 (UCSC)EIF1  -     chr17:41688875-41691646 +  17q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF1  -     17q21.2   [Description]    (hg19-Feb_2009)
EnsemblEIF1 - 17q21.2 [CytoView hg19]  EIF1 - 17q21.2 [CytoView hg38]
Mapping of homologs : NCBIEIF1 [Mapview hg19]  EIF1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA159721 AF083441 AF100737 AJ012375 AK311209
RefSeq transcript (Entrez)NM_005801
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF1
Cluster EST : UnigeneHs.150580 [ NCBI ]
CGAP (NCI)Hs.150580
Alternative Splicing GalleryENSG00000173812
Gene ExpressionEIF1 [ NCBI-GEO ]   EIF1 [ EBI - ARRAY_EXPRESS ]   EIF1 [ SEEK ]   EIF1 [ MEM ]
Gene Expression Viewer (FireBrowse)EIF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10209
GTEX Portal (Tissue expression)EIF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41567   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41567  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41567
Splice isoforms : SwissVarP41567
PhosPhoSitePlusP41567
Domaine pattern : Prosite (Expaxy)SUI1 (PS50296)   
Domains : Interpro (EBI)SUI1    SUI1_euk   
Domain families : Pfam (Sanger)SUI1 (PF01253)   
Domain families : Pfam (NCBI)pfam01253   
Conserved Domain (NCBI)EIF1
DMDM Disease mutations10209
Blocks (Seattle)EIF1
PDB (SRS)2IF1    4KZX    4KZY   
PDB (PDBSum)2IF1    4KZX    4KZY   
PDB (IMB)2IF1    4KZX    4KZY   
PDB (RSDB)2IF1    4KZX    4KZY   
Structural Biology KnowledgeBase2IF1    4KZX    4KZY   
SCOP (Structural Classification of Proteins)2IF1    4KZX    4KZY   
CATH (Classification of proteins structures)2IF1    4KZX    4KZY   
SuperfamilyP41567
Human Protein AtlasENSG00000173812
Peptide AtlasP41567
HPRD15449
IPIIPI00015077   
Protein Interaction databases
DIP (DOE-UCLA)P41567
IntAct (EBI)P41567
FunCoupENSG00000173812
BioGRIDEIF1
STRING (EMBL)EIF1
ZODIACEIF1
Ontologies - Pathways
QuickGOP41567
Ontology : AmiGORNA binding  translation initiation factor activity  nucleus  cytoplasm  translational initiation  regulation of translational initiation  response to stress  translation factor activity, RNA binding  dosage compensation by inactivation of X chromosome  
Ontology : EGO-EBIRNA binding  translation initiation factor activity  nucleus  cytoplasm  translational initiation  regulation of translational initiation  response to stress  translation factor activity, RNA binding  dosage compensation by inactivation of X chromosome  
Pathways : BIOCARTAVEGF, Hypoxia, and Angiogenesis [Genes]    Eukaryotic protein translation [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkEIF1
Atlas of Cancer Signalling NetworkEIF1
Wikipedia pathwaysEIF1
Orthology - Evolution
OrthoDB10209
GeneTree (enSembl)ENSG00000173812
Phylogenetic Trees/Animal Genes : TreeFamEIF1
HOVERGENP41567
HOGENOMP41567
Homologs : HomoloGeneEIF1
Homology/Alignments : Family Browser (UCSC)EIF1
Gene fusions - Rearrangements
Fusion : MitelmanEIF1/MED28 [17q21.2/4p15.32]  
Fusion: TCGAEIF1 17q21.2 MED28 4p15.32 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF1
dbVarEIF1
ClinVarEIF1
1000_GenomesEIF1 
Exome Variant ServerEIF1
ExAC (Exome Aggregation Consortium)EIF1 (select the gene name)
Genetic variants : HAPMAP10209
Genomic Variants (DGV)EIF1 [DGVbeta]
DECIPHEREIF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF1 
Mutations
ICGC Data PortalEIF1 
TCGA Data PortalEIF1 
Broad Tumor PortalEIF1
OASIS PortalEIF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEIF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF1
DgiDB (Drug Gene Interaction Database)EIF1
DoCM (Curated mutations)EIF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF1 (select a term)
intoGenEIF1
Cancer3DEIF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenEIF1
Genetic Testing Registry EIF1
NextProtP41567 [Medical]
TSGene10209
GENETestsEIF1
Target ValidationEIF1
Huge Navigator EIF1 [HugePedia]
snp3D : Map Gene to Disease1020y/TE>
BioCentury BCIQEIF1
ClinGenEIF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10209
Chemical/Pharm GKB GenePA27683
Clinical trialEIF1
Miscellaneous
canSAR (ICR)EIF1 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF1
EVEXEIF1
GoPubMedEIF1
iHOPEIF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:52:24 CEST 2017

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