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EIF1AX (eukaryotic translation initiation factor 1A X-linked)

Identity

Alias (NCBI)EIF1A
EIF1AP1
EIF4C
eIF-1A
eIF-4C
HGNC (Hugo) EIF1AX
HGNC Alias symbeIF-1A
eIF-4C
HGNC Previous nameEIF4C
 EIF1A
HGNC Previous nameeukaryotic translation initiation factor 1A, X chromosome
 eukaryotic translation initiation factor 1A, X-linked
LocusID (NCBI) 1964
Atlas_Id 40423
Location Xp22.12  [Link to chromosome band Xp22]
Location_base_pair Starts at 20124525 and ends at 20141838 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GLIS2 (16p13.3) / EIF1AX (Xp22.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)EIF1AX   3250
Cards
Entrez_Gene (NCBI)EIF1AX    eukaryotic translation initiation factor 1A X-linked
AliasesEIF1A; EIF1AP1; EIF4C; eIF-1A; 
eIF-4C
GeneCards (Weizmann)EIF1AX
Ensembl hg19 (Hinxton)ENSG00000173674 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173674 [Gene_View]  ENSG00000173674 [Sequence]  chrX:20124525-20141838 [Contig_View]  EIF1AX [Vega]
ICGC DataPortalENSG00000173674
TCGA cBioPortalEIF1AX
AceView (NCBI)EIF1AX
Genatlas (Paris)EIF1AX
SOURCE (Princeton)EIF1AX
Genetics Home Reference (NIH)EIF1AX
Genomic and cartography
GoldenPath hg38 (UCSC)EIF1AX  -     chrX:20124525-20141838 -  Xp22.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF1AX  -     Xp22.12   [Description]    (hg19-Feb_2009)
GoldenPathEIF1AX - Xp22.12 [CytoView hg19]  EIF1AX - Xp22.12 [CytoView hg38]
ImmunoBaseENSG00000173674
genome Data Viewer NCBIEIF1AX [Mapview hg19]  
OMIM300186   
Gene and transcription
Genbank (Entrez)AK312320 AL079283 AL832930 BC000793 BC047573
RefSeq transcript (Entrez)NM_001412
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF1AX
Alternative Splicing GalleryENSG00000173674
Gene ExpressionEIF1AX [ NCBI-GEO ]   EIF1AX [ EBI - ARRAY_EXPRESS ]   EIF1AX [ SEEK ]   EIF1AX [ MEM ]
Gene Expression Viewer (FireBrowse)EIF1AX [ Firebrowse - Broad ]
GenevisibleExpression of EIF1AX in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1964
GTEX Portal (Tissue expression)EIF1AX
Human Protein AtlasENSG00000173674-EIF1AX [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP47813   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP47813  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP47813
Splice isoforms : SwissVarP47813
PhosPhoSitePlusP47813
Domaine pattern : Prosite (Expaxy)IF1A (PS01262)    S1_IF1_TYPE (PS50832)   
Domains : Interpro (EBI)NA-bd_OB-fold    RNA-binding_domain_S1_IF1    TIF_eIF-1A    TIF_eIF-1A_CS   
Domain families : Pfam (Sanger)eIF-1a (PF01176)   
Domain families : Pfam (NCBI)pfam01176   
Domain families : Smart (EMBL)eIF1a (SM00652)  
Conserved Domain (NCBI)EIF1AX
Blocks (Seattle)EIF1AX
PDB (RSDB)1D7Q    3ZJY    4KZY    4KZZ    6YBW    6ZMW    6ZP4    7A09   
PDB Europe1D7Q    3ZJY    4KZY    4KZZ    6YBW    6ZMW    6ZP4    7A09   
PDB (PDBSum)1D7Q    3ZJY    4KZY    4KZZ    6YBW    6ZMW    6ZP4    7A09   
PDB (IMB)1D7Q    3ZJY    4KZY    4KZZ    6YBW    6ZMW    6ZP4    7A09   
Structural Biology KnowledgeBase1D7Q    3ZJY    4KZY    4KZZ    6YBW    6ZMW    6ZP4    7A09   
SCOP (Structural Classification of Proteins)1D7Q    3ZJY    4KZY    4KZZ    6YBW    6ZMW    6ZP4    7A09   
CATH (Classification of proteins structures)1D7Q    3ZJY    4KZY    4KZZ    6YBW    6ZMW    6ZP4    7A09   
SuperfamilyP47813
Human Protein Atlas [tissue]ENSG00000173674-EIF1AX [tissue]
Peptide AtlasP47813
HPRD02174
IPIIPI00232533   IPI00642387   
Protein Interaction databases
DIP (DOE-UCLA)P47813
IntAct (EBI)P47813
BioGRIDEIF1AX
STRING (EMBL)EIF1AX
ZODIACEIF1AX
Ontologies - Pathways
QuickGOP47813
Ontology : AmiGORNA binding  translation initiation factor activity  protein binding  cytosol  translational initiation  translation factor activity, RNA binding  
Ontology : EGO-EBIRNA binding  translation initiation factor activity  protein binding  cytosol  translational initiation  translation factor activity, RNA binding  
Pathways : BIOCARTAVEGF, Hypoxia, and Angiogenesis [Genes]    Eukaryotic protein translation [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkEIF1AX
Atlas of Cancer Signalling NetworkEIF1AX
Wikipedia pathwaysEIF1AX
Orthology - Evolution
OrthoDB1964
GeneTree (enSembl)ENSG00000173674
Phylogenetic Trees/Animal Genes : TreeFamEIF1AX
HOGENOMP47813
Homologs : HomoloGeneEIF1AX
Homology/Alignments : Family Browser (UCSC)EIF1AX
Gene fusions - Rearrangements
Fusion : QuiverEIF1AX
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF1AX [hg38]
dbVarEIF1AX
ClinVarEIF1AX
MonarchEIF1AX
1000_GenomesEIF1AX 
Exome Variant ServerEIF1AX
GNOMAD BrowserENSG00000173674
Varsome BrowserEIF1AX
Genomic Variants (DGV)EIF1AX [DGVbeta]
DECIPHEREIF1AX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF1AX 
Mutations
ICGC Data PortalEIF1AX 
TCGA Data PortalEIF1AX 
Broad Tumor PortalEIF1AX
OASIS PortalEIF1AX [ Somatic mutations - Copy number]
Cancer Gene: CensusEIF1AX 
Somatic Mutations in Cancer : COSMICEIF1AX  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEIF1AX
Mutations and Diseases : HGMDEIF1AX
intOGen PortalEIF1AX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF1AX
DgiDB (Drug Gene Interaction Database)EIF1AX
DoCM (Curated mutations)EIF1AX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF1AX (select a term)
intoGenEIF1AX
Cancer3DEIF1AX(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300186   
Orphanet905   
DisGeNETEIF1AX
MedgenEIF1AX
Genetic Testing Registry EIF1AX
NextProtP47813 [Medical]
GENETestsEIF1AX
Target ValidationEIF1AX
Huge Navigator EIF1AX [HugePedia]
ClinGenEIF1AX
Clinical trials, drugs, therapy
MyCancerGenomeEIF1AX
Protein Interactions : CTD
Pharm GKB GenePA27684
PharosP47813
Clinical trialEIF1AX
Miscellaneous
canSAR (ICR)EIF1AX (select the gene name)
HarmonizomeEIF1AX
DataMed IndexEIF1AX
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXEIF1AX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:19:40 CET 2021

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