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EIF1AX (eukaryotic translation initiation factor 1A, X-linked)

Identity

Alias_namesEIF4C
EIF1A
eukaryotic translation initiation factor 1A
Alias_symbol (synonym)eIF-1A
eIF-4C
Other aliasEIF1AP1
HGNC (Hugo) EIF1AX
LocusID (NCBI) 1964
Atlas_Id 40423
Location Xp22.12  [Link to chromosome band Xp22]
Location_base_pair Starts at 20142636 and ends at 20159966 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GLIS2 (16p13.3) / EIF1AX (Xp22.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EIF1AX   3250
Cards
Entrez_Gene (NCBI)EIF1AX  1964  eukaryotic translation initiation factor 1A, X-linked
AliasesEIF1A; EIF1AP1; EIF4C; eIF-1A; 
eIF-4C
GeneCards (Weizmann)EIF1AX
Ensembl hg19 (Hinxton)ENSG00000173674 [Gene_View]  chrX:20142636-20159966 [Contig_View]  EIF1AX [Vega]
Ensembl hg38 (Hinxton)ENSG00000173674 [Gene_View]  chrX:20142636-20159966 [Contig_View]  EIF1AX [Vega]
ICGC DataPortalENSG00000173674
TCGA cBioPortalEIF1AX
AceView (NCBI)EIF1AX
Genatlas (Paris)EIF1AX
WikiGenes1964
SOURCE (Princeton)EIF1AX
Genetics Home Reference (NIH)EIF1AX
Genomic and cartography
GoldenPath hg19 (UCSC)EIF1AX  -     chrX:20142636-20159966 -  Xp22.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)EIF1AX  -     Xp22.12   [Description]    (hg38-Dec_2013)
EnsemblEIF1AX - Xp22.12 [CytoView hg19]  EIF1AX - Xp22.12 [CytoView hg38]
Mapping of homologs : NCBIEIF1AX [Mapview hg19]  EIF1AX [Mapview hg38]
OMIM300186   
Gene and transcription
Genbank (Entrez)AK312320 AL079283 AL832930 BC000793 BC047573
RefSeq transcript (Entrez)NM_001412
RefSeq genomic (Entrez)NC_000023 NC_018934 NT_167197 NW_004929438
Consensus coding sequences : CCDS (NCBI)EIF1AX
Cluster EST : UnigeneHs.522590 [ NCBI ]
CGAP (NCI)Hs.522590
Alternative Splicing GalleryENSG00000173674
Gene ExpressionEIF1AX [ NCBI-GEO ]   EIF1AX [ EBI - ARRAY_EXPRESS ]   EIF1AX [ SEEK ]   EIF1AX [ MEM ]
Gene Expression Viewer (FireBrowse)EIF1AX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1964
GTEX Portal (Tissue expression)EIF1AX
Protein : pattern, domain, 3D structure
UniProt/SwissProtP47813   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP47813  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP47813
Splice isoforms : SwissVarP47813
PhosPhoSitePlusP47813
Domaine pattern : Prosite (Expaxy)IF1A (PS01262)    S1_IF1_TYPE (PS50832)   
Domains : Interpro (EBI)NA-bd_OB-fold    RNA-binding_domain_S1_IF1    TIF_eIF-1A    TIF_eIF-1A_CS   
Domain families : Pfam (Sanger)eIF-1a (PF01176)   
Domain families : Pfam (NCBI)pfam01176   
Domain families : Smart (EMBL)eIF1a (SM00652)  
Domain structure : Prodom (Prabi Lyon)TIF_eIF-1A (PD005579)   
Conserved Domain (NCBI)EIF1AX
DMDM Disease mutations1964
Blocks (Seattle)EIF1AX
PDB (SRS)1D7Q    3ZJY    4KZY    4KZZ   
PDB (PDBSum)1D7Q    3ZJY    4KZY    4KZZ   
PDB (IMB)1D7Q    3ZJY    4KZY    4KZZ   
PDB (RSDB)1D7Q    3ZJY    4KZY    4KZZ   
Structural Biology KnowledgeBase1D7Q    3ZJY    4KZY    4KZZ   
SCOP (Structural Classification of Proteins)1D7Q    3ZJY    4KZY    4KZZ   
CATH (Classification of proteins structures)1D7Q    3ZJY    4KZY    4KZZ   
SuperfamilyP47813
Human Protein AtlasENSG00000173674
Peptide AtlasP47813
HPRD02174
IPIIPI00232533   IPI00642387   
Protein Interaction databases
DIP (DOE-UCLA)P47813
IntAct (EBI)P47813
FunCoupENSG00000173674
BioGRIDEIF1AX
STRING (EMBL)EIF1AX
ZODIACEIF1AX
Ontologies - Pathways
QuickGOP47813
Ontology : AmiGOtranslation initiation factor activity  protein binding  cytosol  translational initiation  translation factor activity, RNA binding  poly(A) RNA binding  
Ontology : EGO-EBItranslation initiation factor activity  protein binding  cytosol  translational initiation  translation factor activity, RNA binding  poly(A) RNA binding  
Pathways : BIOCARTAVEGF, Hypoxia, and Angiogenesis [Genes]    Eukaryotic protein translation [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkEIF1AX
Atlas of Cancer Signalling NetworkEIF1AX
Wikipedia pathwaysEIF1AX
Orthology - Evolution
OrthoDB1964
GeneTree (enSembl)ENSG00000173674
Phylogenetic Trees/Animal Genes : TreeFamEIF1AX
HOVERGENP47813
HOGENOMP47813
Homologs : HomoloGeneEIF1AX
Homology/Alignments : Family Browser (UCSC)EIF1AX
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF1AX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF1AX
dbVarEIF1AX
ClinVarEIF1AX
1000_GenomesEIF1AX 
Exome Variant ServerEIF1AX
ExAC (Exome Aggregation Consortium)EIF1AX (select the gene name)
Genetic variants : HAPMAP1964
Genomic Variants (DGV)EIF1AX [DGVbeta]
DECIPHER (Syndromes)X:20142636-20159966  ENSG00000173674
CONAN: Copy Number AnalysisEIF1AX 
Mutations
ICGC Data PortalEIF1AX 
TCGA Data PortalEIF1AX 
Broad Tumor PortalEIF1AX
OASIS PortalEIF1AX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF1AX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEIF1AX
intOGen PortalEIF1AX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF1AX
DgiDB (Drug Gene Interaction Database)EIF1AX
DoCM (Curated mutations)EIF1AX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF1AX (select a term)
intoGenEIF1AX
Cancer3DEIF1AX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300186   
Orphanet905   
MedgenEIF1AX
Genetic Testing Registry EIF1AX
NextProtP47813 [Medical]
TSGene1964
GENETestsEIF1AX
Huge Navigator EIF1AX [HugePedia]
snp3D : Map Gene to Disease1964
BioCentury BCIQEIF1AX
ClinGenEIF1AX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1964
Chemical/Pharm GKB GenePA27684
Clinical trialEIF1AX
Miscellaneous
canSAR (ICR)EIF1AX (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF1AX
EVEXEIF1AX
GoPubMedEIF1AX
iHOPEIF1AX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:59:51 CEST 2017

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