Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EIF2A (eukaryotic translation initiation factor 2A, 65kDa)

Identity

Other namesEIF-2A
MST089
MSTP004
MSTP089
HGNC (Hugo) EIF2A
LocusID (NCBI) 83939
Location 3q25.1
Location_base_pair Starts at 150264574 and ends at 150303803 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)EIF2A   3254
Entrez_Gene (NCBI)EIF2A  83939  eukaryotic translation initiation factor 2A, 65kDa
Cards
GeneCards (Weizmann)EIF2A
Ensembl (Hinxton)ENSG00000144895 [Gene_View]  chr3:150264574-150303803 [Contig_View]  EIF2A [Vega]
AceView (NCBI)EIF2A
Genatlas (Paris)EIF2A
SOURCE (Stanford)NM_032025
Genomic and cartography
GoldenPath (UCSC)EIF2A  -  3q25.1   chr3:150264574-150303803 +  3q25.1   [Description]    (hg19-Feb_2009)
EnsemblEIF2A - 3q25.1 [CytoView]
Mapping of homologs : NCBIEIF2A [Mapview]
OMIM609234   
Gene and transcription
Genbank (Entrez)AF109358 AF172818 AF212241 AF497978 AI560242
RefSeq transcript (SRS)NM_032025
RefSeq transcript (Entrez)NM_032025
RefSeq genomic (SRS)AC_000135 NC_000003 NC_018914 NT_005612 NW_001838884 NW_004078013
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NT_005612 NW_001838884 NW_004078013
Consensus coding sequences : CCDS (NCBI)EIF2A
Cluster EST : UnigeneHs.655782 [ SRS ] Hs.655782 [ NCBI ]
CGAP (NCI)Hs.655782
Alternative Splicing : Fast-db (Paris)GSHG0021247
Alternative Splicing GalleryENSG00000144895
Gene ExpressionEIF2A [ NCBI-GEO ]   EIF2A [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BY44 (SRS) Q9BY44 (Uniprot)
NextProtQ9BY44
With graphics : InterProQ9BY44
Splice isoforms : SwissVarQ9BY44(Swissvar)
Domaine pattern : Prosite (SRS)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (SRS)TIF2A    TIF2A_beta_prop-like    WD40/YVTN_repeat-like_dom   
Domains : Interpro (EBI)TIF2A    TIF2A_beta_prop-like    WD40/YVTN_repeat-like_dom   
Related proteins : CluSTrQ9BY44
Domain families : Pfam (SRS)eIF2A (PF08662)   
Domain families : Pfam (Sanger)eIF2A (PF08662)   
Domain families : Pfam (NCBI)pfam08662   
DMDM83939
Blocks (Seattle)Q9BY44
Human Protein AtlasENSG00000144895
HPRD11739
IPIIPI00939283   IPI00012462   IPI00945725   IPI00845305   IPI00982376   IPI00946890   IPI00946070   IPI00945881   IPI00945739   IPI00797021   IPI00945560   
Protein Interaction databases
DIP (DOE-UCLA)Q9BY44
IntAct (EBI)Q9BY44
FunCoupENSG00000144895
REACTOMEEIF2A
Protein Interaction Database83939
BioGRIDEIF2A
InParanoidQ9BY44
Interologous Interaction database Q9BY44
IntegromeDBEIF2A
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)EIF2A
SNP (GeneSNP Utah)EIF2A
SNP : HGBaseEIF2A
Genetic variants : HAPMAPEIF2A
Somatic Mutations in Cancer : COSMICEIF2A 
CONAN: Copy Number AnalysisEIF2A 
Mutations and Diseases : HGMDEIF2A
OMIM609234   
GENETests609234   
Disease Genetic AssociationEIF2A
Huge Navigator EIF2A [HugePedia]  EIF2A [HugeCancerGEM]
Genomic VariantsEIF2A  EIF2A [DGVbeta]
snp3D : Map Gene to Disease83939
General knowledge
Homologs : HomoloGeneEIF2A
Homology/Alignments : Family Browser (UCSC)EIF2A
Phylogenetic Trees/Animal Genes : TreeFamEIF2A
Chemical/Protein Interactions : CTD83939
Chemical/Pharm GKB GenePA143485453
Clinical trialEIF2A
Cancer Resource (Charite)ENSG00000144895
Ontology : AmiGOtRNA binding  translation initiation factor activity  protein binding  cytoplasm  eukaryotic translation initiation factor 2 complex  regulation of translation  protein phosphorylation  positive regulation of signal transduction  SREBP signaling pathway  ribosome assembly  ribosome binding  
Ontology : EGO-EBItRNA binding  translation initiation factor activity  protein binding  cytoplasm  eukaryotic translation initiation factor 2 complex  regulation of translation  protein phosphorylation  positive regulation of signal transduction  SREBP signaling pathway  ribosome assembly  ribosome binding  
Other databases
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
PubGeneEIF2A
iHOPEIF2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:27:05 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.