Identity
HGNC
LOCATION
2p23.3
LOCUSID
ALIAS
EIF-2B,EIF2B,EIF2Bdelta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8890
MIM: 606687
HGNC: 3260
Ensembl: ENSG00000115211
Variants:
dbSNP: 8890
ClinVar: 8890
TCGA: ENSG00000115211
COSMIC: EIF2B4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34663487 | 2022 | Leukodystrophy Due to eIF2B Mutations in Adults. | 1 |
| 34663487 | 2022 | Leukodystrophy Due to eIF2B Mutations in Adults. | 1 |
| 25600065 | 2015 | Adult-onset vanishing white matter disease with novel missense mutations in a subunit of translational regulator, EIF2B4. | 3 |
| 25779044 | 2015 | DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation. | 55 |
| 25600065 | 2015 | Adult-onset vanishing white matter disease with novel missense mutations in a subunit of translational regulator, EIF2B4. | 3 |
| 25779044 | 2015 | DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation. | 55 |
| 22737209 | 2012 | Developmental splicing deregulation in leukodystrophies related to EIF2B mutations. | 8 |
| 22737209 | 2012 | Developmental splicing deregulation in leukodystrophies related to EIF2B mutations. | 8 |
| 21503715 | 2011 | [Vanishing white matter disease: a stress-related leukodystrophy]. | 1 |
| 21560189 | 2011 | Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes. | 35 |
| 21503715 | 2011 | [Vanishing white matter disease: a stress-related leukodystrophy]. | 1 |
| 21560189 | 2011 | Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes. | 35 |
| 20532202 | 2010 | Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes. | 42 |
| 20709751 | 2010 | Regulation of the unfolded protein response by eif2Bdelta isoforms. | 10 |
| 20734064 | 2010 | A large-scale candidate gene association study of age at menarche and age at natural menopause. | 57 |
Citation
Dessen P
EIF2B4 (eukaryotic translation initiation factor 2B subunit delta)
Atlas Genet Cytogenet Oncol Haematol. 2010-12-01
Online version: http://atlasgeneticsoncology.org/gene/51837/eif2b4
