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EIF3D (eukaryotic translation initiation factor 3 subunit D)

Identity

Alias_namesEIF3S7
eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa
eukaryotic translation initiation factor 3, subunit D
Alias_symbol (synonym)eIF3-p66
eIF3-zeta
eIF3d
Other alias
HGNC (Hugo) EIF3D
LocusID (NCBI) 8664
Atlas_Id 54279
Location 22q12.3  [Link to chromosome band 22q12]
Location_base_pair Starts at 36510850 and ends at 36529230 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EIF3D (22q12.3) / EIF3D (22q12.3)EIF3D (22q12.3) / EIF5B (2q11.2)EIF3D (22q12.3) / FAM111A (11q12.1)
EIF3D (22q12.3) / IBSP (4q22.1)EIF3D (22q12.3) / NCL (2q37.1)EIF3D (22q12.3) / PSMD13 (11p15.5)
EIF3D (22q12.3) / S100A2 (1q21.3)EIF3D (22q12.3) / TNRC18 (7p22.1)EIF3D (22q12.3) / UCP2 (11q13.4)
FOXRED2 (22q12.3) / EIF3D (22q12.3)MYH9 (22q12.3) / EIF3D (22q12.3)NF2 (22q12.2) / EIF3D (22q12.3)
PEG10 (7q21.3) / EIF3D (22q12.3)S100A2 (1q21.3) / EIF3D (22q12.3)SMOX (20p13) / EIF3D (22q12.3)
NF2 22q12.2 / EIF3D 22q12.3SMOX 20p13 / EIF3D 22q12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EIF3D   3278
Cards
Entrez_Gene (NCBI)EIF3D  8664  eukaryotic translation initiation factor 3 subunit D
AliasesEIF3S7; eIF3-p66; eIF3-zeta
GeneCards (Weizmann)EIF3D
Ensembl hg19 (Hinxton)ENSG00000100353 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100353 [Gene_View]  chr22:36510850-36529230 [Contig_View]  EIF3D [Vega]
ICGC DataPortalENSG00000100353
TCGA cBioPortalEIF3D
AceView (NCBI)EIF3D
Genatlas (Paris)EIF3D
WikiGenes8664
SOURCE (Princeton)EIF3D
Genetics Home Reference (NIH)EIF3D
Genomic and cartography
GoldenPath hg38 (UCSC)EIF3D  -     chr22:36510850-36529230 -  22q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF3D  -     22q12.3   [Description]    (hg19-Feb_2009)
EnsemblEIF3D - 22q12.3 [CytoView hg19]  EIF3D - 22q12.3 [CytoView hg38]
Mapping of homologs : NCBIEIF3D [Mapview hg19]  EIF3D [Mapview hg38]
OMIM603915   
Gene and transcription
Genbank (Entrez)AK300199 AK301284 AK303884 AK312939 AW575097
RefSeq transcript (Entrez)NM_003753
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF3D
Cluster EST : UnigeneHs.55682 [ NCBI ]
CGAP (NCI)Hs.55682
Alternative Splicing GalleryENSG00000100353
Gene ExpressionEIF3D [ NCBI-GEO ]   EIF3D [ EBI - ARRAY_EXPRESS ]   EIF3D [ SEEK ]   EIF3D [ MEM ]
Gene Expression Viewer (FireBrowse)EIF3D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8664
GTEX Portal (Tissue expression)EIF3D
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15371   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15371  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15371
Splice isoforms : SwissVarO15371
PhosPhoSitePlusO15371
Domains : Interpro (EBI)eIF3d   
Domain families : Pfam (Sanger)eIF-3_zeta (PF05091)   
Domain families : Pfam (NCBI)pfam05091   
Conserved Domain (NCBI)EIF3D
DMDM Disease mutations8664
Blocks (Seattle)EIF3D
SuperfamilyO15371
Human Protein AtlasENSG00000100353
Peptide AtlasO15371
HPRD04888
IPIIPI00006181   IPI00791086   IPI00789582   IPI00797054   IPI00903191   IPI00879112   IPI00879735   
Protein Interaction databases
DIP (DOE-UCLA)O15371
IntAct (EBI)O15371
FunCoupENSG00000100353
BioGRIDEIF3D
STRING (EMBL)EIF3D
ZODIACEIF3D
Ontologies - Pathways
QuickGOO15371
Ontology : AmiGOformation of cytoplasmic translation initiation complex  cap-dependent translational initiation  RNA binding  translation initiation factor activity  translation initiation factor activity  protein binding  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  membrane  positive regulation of translation  eukaryotic translation initiation factor 3 complex, eIF3m  IRES-dependent viral translational initiation  viral translational termination-reinitiation  mRNA cap binding  positive regulation of mRNA binding  
Ontology : EGO-EBIformation of cytoplasmic translation initiation complex  cap-dependent translational initiation  RNA binding  translation initiation factor activity  translation initiation factor activity  protein binding  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  membrane  positive regulation of translation  eukaryotic translation initiation factor 3 complex, eIF3m  IRES-dependent viral translational initiation  viral translational termination-reinitiation  mRNA cap binding  positive regulation of mRNA binding  
Pathways : KEGGRNA transport   
NDEx NetworkEIF3D
Atlas of Cancer Signalling NetworkEIF3D
Wikipedia pathwaysEIF3D
Orthology - Evolution
OrthoDB8664
GeneTree (enSembl)ENSG00000100353
Phylogenetic Trees/Animal Genes : TreeFamEIF3D
HOVERGENO15371
HOGENOMO15371
Homologs : HomoloGeneEIF3D
Homology/Alignments : Family Browser (UCSC)EIF3D
Gene fusions - Rearrangements
Fusion : MitelmanMYH9/EIF3D [22q12.3/22q12.3]  [t(22;22)(q12;q12)]  
Fusion : MitelmanNF2/EIF3D [22q12.2/22q12.3]  [t(22;22)(q12;q12)]  
Fusion : MitelmanSMOX/EIF3D [20p13/22q12.3]  [t(20;22)(p13;q12)]  
Fusion: TCGANF2 22q12.2 EIF3D 22q12.3 BRCA
Fusion: TCGASMOX 20p13 EIF3D 22q12.3 LGG
Fusion Cancer (Beijing)EIF3D [22q12.3]  -  IBSP [4q22.1]  [FUSC002268]  [FUSC002268]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF3D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF3D
dbVarEIF3D
ClinVarEIF3D
1000_GenomesEIF3D 
Exome Variant ServerEIF3D
ExAC (Exome Aggregation Consortium)EIF3D (select the gene name)
Genetic variants : HAPMAP8664
Genomic Variants (DGV)EIF3D [DGVbeta]
DECIPHEREIF3D [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF3D 
Mutations
ICGC Data PortalEIF3D 
TCGA Data PortalEIF3D 
Broad Tumor PortalEIF3D
OASIS PortalEIF3D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF3D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEIF3D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF3D
DgiDB (Drug Gene Interaction Database)EIF3D
DoCM (Curated mutations)EIF3D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF3D (select a term)
intoGenEIF3D
Cancer3DEIF3D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603915   
Orphanet
MedgenEIF3D
Genetic Testing Registry EIF3D
NextProtO15371 [Medical]
TSGene8664
GENETestsEIF3D
Target ValidationEIF3D
Huge Navigator EIF3D [HugePedia]
snp3D : Map Gene to Disease8664
BioCentury BCIQEIF3D
ClinGenEIF3D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8664
Chemical/Pharm GKB GenePA162384740
Clinical trialEIF3D
Miscellaneous
canSAR (ICR)EIF3D (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF3D
EVEXEIF3D
GoPubMedEIF3D
iHOPEIF3D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:32:20 CEST 2017

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